登録情報 | データベース: PDB / ID: 2n10 |
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タイトル | Solution structure of MyUb (1080-1131) of human Myosin VI |
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要素 | Unconventional myosin-VI |
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キーワード | MOTOR PROTEIN / PROTEIN TRANSPORT |
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機能・相同性 | 機能・相同性情報
regulation of secretion / minus-end directed microfilament motor activity / unconventional myosin complex / actin filament-based movement / inner ear auditory receptor cell differentiation / clathrin-coated vesicle membrane / Gap junction degradation / vesicle transport along actin filament / Trafficking of AMPA receptors / RHOBTB1 GTPase cycle ...regulation of secretion / minus-end directed microfilament motor activity / unconventional myosin complex / actin filament-based movement / inner ear auditory receptor cell differentiation / clathrin-coated vesicle membrane / Gap junction degradation / vesicle transport along actin filament / Trafficking of AMPA receptors / RHOBTB1 GTPase cycle / inner ear morphogenesis / microfilament motor activity / cytoskeletal motor activity / filamentous actin / microvillus / RHOU GTPase cycle / DNA damage response, signal transduction by p53 class mediator / endocytic vesicle / autophagosome / RHOBTB2 GTPase cycle / clathrin-coated pit / ruffle / filopodium / actin filament / actin filament organization / sensory perception of sound / intracellular protein transport / protein localization / ADP binding / ruffle membrane / endocytosis / actin filament binding / actin cytoskeleton / apical part of cell / actin binding / cell cortex / cytoplasmic vesicle / nuclear membrane / calmodulin binding / endosome / response to xenobiotic stimulus / lysosomal membrane / perinuclear region of cytoplasm / Golgi apparatus / extracellular exosome / nucleoplasm / ATP binding / identical protein binding / membrane / nucleus / plasma membrane / cytoplasm / cytosol類似検索 - 分子機能 : / Myosin VI, lever arm / Myosin VI, cargo binding domain / Class VI myosin, motor domain / Myosin VI cargo binding domain / Myosin S1 fragment, N-terminal / Myosin, N-terminal, SH3-like / Myosin N-terminal SH3-like domain profile. / Myosin head, motor domain / Myosin head (motor domain) ...: / Myosin VI, lever arm / Myosin VI, cargo binding domain / Class VI myosin, motor domain / Myosin VI cargo binding domain / Myosin S1 fragment, N-terminal / Myosin, N-terminal, SH3-like / Myosin N-terminal SH3-like domain profile. / Myosin head, motor domain / Myosin head (motor domain) / Myosin motor domain profile. / Myosin. Large ATPases. / Kinesin motor domain superfamily / P-loop containing nucleoside triphosphate hydrolase類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | 溶液NMR / simulated annealing |
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Model details | lowest energy, model1 |
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データ登録者 | He, F. / Ehlinger, A. / Walters, K. |
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資金援助 | 米国, 2件 組織 | 認可番号 | 国 |
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National Institutes of Health/National Cancer Institute (NIH/NCI) | CA136472 | 米国 | National Institutes of Health/National Cancer Institute (NIH/NCI) | 1ZIABC011627 | 米国 |
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引用 | ジャーナル: Cell Rep / 年: 2016 タイトル: Myosin VI Contains a Compact Structural Motif that Binds to Ubiquitin Chains. 著者: He, F. / Wollscheid, H.P. / Nowicka, U. / Biancospino, M. / Valentini, E. / Ehlinger, A. / Acconcia, F. / Magistrati, E. / Polo, S. / Walters, K.J. |
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履歴 | 登録 | 2015年3月20日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2016年3月9日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2016年3月30日 | Group: Database references |
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改定 1.2 | 2016年4月6日 | Group: Database references |
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改定 1.3 | 2016年4月27日 | Group: Structure summary |
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改定 1.4 | 2021年10月13日 | Group: Data collection / Database references カテゴリ: database_2 / pdbx_nmr_software / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_nmr_software.name / _struct_ref_seq_dif.details |
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改定 2.0 | 2021年10月20日 | Group: Advisory / Atomic model ...Advisory / Atomic model / Author supporting evidence / Data collection / Database references / Derived calculations / Experimental preparation / Other / Refinement description / Source and taxonomy / Structure summary カテゴリ: atom_site / entity_src_gen ...atom_site / entity_src_gen / pdbx_audit_support / pdbx_database_related / pdbx_database_status / pdbx_nmr_ensemble / pdbx_nmr_exptl / pdbx_nmr_exptl_sample / pdbx_nmr_exptl_sample_conditions / pdbx_nmr_refine / pdbx_nmr_sample_details / pdbx_nmr_software / pdbx_nmr_spectrometer / pdbx_poly_seq_scheme / pdbx_unobs_or_zero_occ_residues / pdbx_validate_close_contact / pdbx_validate_torsion / struct / struct_conf Item: _entity_src_gen.gene_src_common_name / _entity_src_gen.pdbx_beg_seq_num ..._entity_src_gen.gene_src_common_name / _entity_src_gen.pdbx_beg_seq_num / _entity_src_gen.pdbx_end_seq_num / _entity_src_gen.pdbx_seq_type / _pdbx_database_status.SG_entry / _pdbx_database_status.deposit_site / _pdbx_nmr_ensemble.conformer_selection_criteria / _pdbx_nmr_ensemble.conformers_calculated_total_number / _pdbx_nmr_exptl.sample_state / _pdbx_nmr_exptl.spectrometer_id / _pdbx_nmr_exptl_sample.component / _pdbx_nmr_exptl_sample_conditions.ionic_strength_units / _pdbx_nmr_exptl_sample_conditions.label / _pdbx_nmr_exptl_sample_conditions.pH_units / _pdbx_nmr_refine.software_ordinal / _pdbx_nmr_sample_details.contents / _pdbx_nmr_sample_details.label / _pdbx_nmr_sample_details.type / _pdbx_nmr_software.classification / _pdbx_nmr_spectrometer.type / _pdbx_poly_seq_scheme.auth_mon_id / _pdbx_poly_seq_scheme.auth_seq_num / _pdbx_poly_seq_scheme.pdb_mon_id / _struct.pdbx_CASP_flag / _struct_conf.pdbx_PDB_helix_id 解説: Atoms with unrealistic or zero occupancies / Provider: author / タイプ: Coordinate replacement |
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改定 2.1 | 2023年6月14日 | Group: Other / カテゴリ: pdbx_database_status / Item: _pdbx_database_status.status_code_nmr_data |
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改定 2.2 | 2024年5月15日 | Group: Data collection / Database references / カテゴリ: chem_comp_atom / chem_comp_bond / database_2 / Item: _database_2.pdbx_DOI |
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