- PDB-2n02: Solution structure of the A147T variant of the mitochondrial tran... -
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Basic information
Entry
Database: PDB / ID: 2n02
Title
Solution structure of the A147T variant of the mitochondrial translocator protein (tspo) in complex with pk11195
Components
Translocator protein
Keywords
MEMBRANE PROTEIN / TRANSLOCATOR PROTEIN (TSPO) / PROTEIN-LIGAND COMPLEX / MITOCHONDRIA / PK11195 / PERIPHERAL BENZODIAZEPINE RECEPTOR / A147T
Function / homology
Function and homology information
negative regulation of corticosterone secretion / Pregnenolone biosynthesis / negative regulation of ATP metabolic process / response to vitamin B1 / contact inhibition / peripheral nervous system axon regeneration / maintenance of protein location in mitochondrion / benzodiazepine receptor activity / regulation of steroid biosynthetic process / establishment of protein localization to mitochondrion ...negative regulation of corticosterone secretion / Pregnenolone biosynthesis / negative regulation of ATP metabolic process / response to vitamin B1 / contact inhibition / peripheral nervous system axon regeneration / maintenance of protein location in mitochondrion / benzodiazepine receptor activity / regulation of steroid biosynthetic process / establishment of protein localization to mitochondrion / glial cell migration / response to acetylcholine / cellular hypotonic response / androgen binding / negative regulation of nitric oxide biosynthetic process / steroid biosynthetic process / positive regulation of calcium ion transport / negative regulation of mitophagy / positive regulation of programmed necrotic cell death / chloride transport / response to manganese ion / lipid transport / cellular response to zinc ion / negative regulation of glial cell proliferation / adrenal gland development / cholesterol binding / positive regulation of mitochondrial depolarization / response to testosterone / behavioral response to pain / positive regulation of glial cell proliferation / negative regulation of tumor necrosis factor production / monoatomic ion transport / negative regulation of protein ubiquitination / cholesterol homeostasis / response to progesterone / positive regulation of reactive oxygen species metabolic process / cellular response to lipopolysaccharide / transmembrane transporter binding / mitochondrial outer membrane / response to xenobiotic stimulus / positive regulation of apoptotic process / endoplasmic reticulum / mitochondrion / membrane / cytosol Similarity search - Function
TspO/MBR protein / TspO/MBR-related protein / TspO/MBR-related superfamily / TspO/MBR family / Ferritin / Up-down Bundle / Mainly Alpha Similarity search - Domain/homology
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