登録情報 | データベース: PDB / ID: 2m9e |
---|
タイトル | NMR solution structure of Pin1 WW domain mutant 5-1 |
---|
要素 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
---|
キーワード | ISOMERASE / N-glycosylation / Enhanced Aromatic Sequon / WW domain / CH-pi interaction |
---|
機能・相同性 | 機能・相同性情報
cis-trans isomerase activity / phosphothreonine residue binding / negative regulation of cell motility / ubiquitin ligase activator activity / regulation of protein localization to nucleus / GTPase activating protein binding / postsynaptic cytosol / mitogen-activated protein kinase kinase binding / regulation of mitotic nuclear division / negative regulation of SMAD protein signal transduction ...cis-trans isomerase activity / phosphothreonine residue binding / negative regulation of cell motility / ubiquitin ligase activator activity / regulation of protein localization to nucleus / GTPase activating protein binding / postsynaptic cytosol / mitogen-activated protein kinase kinase binding / regulation of mitotic nuclear division / negative regulation of SMAD protein signal transduction / PI5P Regulates TP53 Acetylation / negative regulation of amyloid-beta formation / cytoskeletal motor activity / phosphoserine residue binding / RHO GTPases Activate NADPH Oxidases / protein peptidyl-prolyl isomerization / positive regulation of protein dephosphorylation / ciliary basal body / positive regulation of GTPase activity / regulation of cytokinesis / negative regulation of protein binding / peptidylprolyl isomerase / peptidyl-prolyl cis-trans isomerase activity / Negative regulators of DDX58/IFIH1 signaling / phosphoprotein binding / synapse organization / negative regulation of transforming growth factor beta receptor signaling pathway / regulation of protein phosphorylation / regulation of protein stability / tau protein binding / neuron differentiation / negative regulation of protein catabolic process / negative regulation of ERK1 and ERK2 cascade / ISG15 antiviral mechanism / beta-catenin binding / positive regulation of canonical Wnt signaling pathway / positive regulation of protein binding / midbody / regulation of gene expression / Regulation of TP53 Activity through Phosphorylation / protein stabilization / response to hypoxia / nuclear speck / positive regulation of protein phosphorylation / cell cycle / glutamatergic synapse / positive regulation of transcription by RNA polymerase II / nucleoplasm / nucleus / cytoplasm / cytosol類似検索 - 分子機能 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site / PpiC-type peptidyl-prolyl cis-trans isomerase signature. / PPIC-type PPIASE domain / PpiC-type peptidyl-prolyl cis-trans isomerase family profile. / Peptidyl-prolyl cis-trans isomerase, PpiC-type / WW domain / WW/rsp5/WWP domain signature. / WW domain superfamily / WW/rsp5/WWP domain profile. / Domain with 2 conserved Trp (W) residues ...Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site / PpiC-type peptidyl-prolyl cis-trans isomerase signature. / PPIC-type PPIASE domain / PpiC-type peptidyl-prolyl cis-trans isomerase family profile. / Peptidyl-prolyl cis-trans isomerase, PpiC-type / WW domain / WW/rsp5/WWP domain signature. / WW domain superfamily / WW/rsp5/WWP domain profile. / Domain with 2 conserved Trp (W) residues / WW domain / Peptidyl-prolyl cis-trans isomerase domain superfamily類似検索 - ドメイン・相同性 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1類似検索 - 構成要素 |
---|
生物種 | Homo sapiens (ヒト) |
---|
手法 | 溶液NMR / molecular dynamics |
---|
データ登録者 | Enck, S. / Chen, W. / Price, J.L. / Powers, E.T. / Wong, C. / Dyson, H.J. / Kelly, J.W. |
---|
引用 | ジャーナル: J.Am.Chem.Soc. / 年: 2013 タイトル: Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins. 著者: Chen, W. / Enck, S. / Price, J.L. / Powers, D.L. / Powers, E.T. / Wong, C.H. / Dyson, H.J. / Kelly, J.W. |
---|
履歴 | 登録 | 2013年6月7日 | 登録サイト: BMRB / 処理サイト: RCSB |
---|
改定 1.0 | 2013年6月26日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2013年7月3日 | Group: Database references |
---|
改定 1.2 | 2013年7月17日 | Group: Database references |
---|
改定 1.3 | 2023年6月14日 | Group: Data collection / Database references / Other カテゴリ: database_2 / pdbx_database_status / pdbx_nmr_software Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_nmr_data / _pdbx_nmr_software.name |
---|
改定 1.4 | 2024年5月15日 | Group: Data collection / Database references / カテゴリ: chem_comp_atom / chem_comp_bond / database_2 / Item: _database_2.pdbx_DOI |
---|
|
---|