登録情報 | データベース: PDB / ID: 2lri |
---|
タイトル | NMR structure of the second PHD finger of AIRE (AIRE-PHD2) |
---|
要素 | Autoimmune regulator |
---|
キーワード | TRANSCRIPTION / Zn binding protein domain / APECED |
---|
機能・相同性 | 機能・相同性情報
peripheral T cell tolerance induction / central tolerance induction to self antigen / regulation of thymocyte migration / thymus epithelium morphogenesis / negative thymic T cell selection / female germ cell nucleus / humoral immune response / male germ cell nucleus / translation regulator activity / positive regulation of chemokine production ...peripheral T cell tolerance induction / central tolerance induction to self antigen / regulation of thymocyte migration / thymus epithelium morphogenesis / negative thymic T cell selection / female germ cell nucleus / humoral immune response / male germ cell nucleus / translation regulator activity / positive regulation of chemokine production / RNA polymerase II transcription regulatory region sequence-specific DNA binding / histone binding / transcription by RNA polymerase II / nuclear body / immune response / chromatin binding / positive regulation of DNA-templated transcription / regulation of DNA-templated transcription / positive regulation of transcription by RNA polymerase II / zinc ion binding / identical protein binding / nucleus / cytoplasm類似検索 - 分子機能 Autoimmune regulator, AIRE / AIRE, PHD finger 2 / HSR domain / Nuclear body protein Sp110/Sp140/Sp140L / HSR domain / HSR domain profile. / SAND domain / SAND domain / SAND domain profile. / SAND domain ...Autoimmune regulator, AIRE / AIRE, PHD finger 2 / HSR domain / Nuclear body protein Sp110/Sp140/Sp140L / HSR domain / HSR domain profile. / SAND domain / SAND domain / SAND domain profile. / SAND domain / SAND-like domain superfamily / Zinc/RING finger domain, C3HC4 (zinc finger) / Herpes Virus-1 / Zinc finger, PHD-type, conserved site / PHD-finger / Zinc finger PHD-type signature. / Zinc finger PHD-type profile. / Zinc finger, PHD-finger / Zinc finger, PHD-type / PHD zinc finger / Zinc finger, FYVE/PHD-type / Zinc finger, RING/FYVE/PHD-type / 2-Layer Sandwich / Alpha Beta類似検索 - ドメイン・相同性 |
---|
生物種 | Homo sapiens (ヒト) |
---|
手法 | 溶液NMR / simulated annealing |
---|
Model details | lowest energy, model 1 |
---|
データ登録者 | Gaetani, M. / Chignola, F. / Mollica, L. / Quilici, G. / Mannella, V. / Spiliotopoulos, D. / Musco, G. |
---|
引用 | ジャーナル: Nucleic Acids Res. / 年: 2012 タイトル: AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome. 著者: Gaetani, M. / Matafora, V. / Saare, M. / Spiliotopoulos, D. / Mollica, L. / Quilici, G. / Chignola, F. / Mannella, V. / Zucchelli, C. / Peterson, P. / Bachi, A. / Musco, G. |
---|
履歴 | 登録 | 2012年4月3日 | 登録サイト: BMRB / 処理サイト: RCSB |
---|
改定 1.0 | 2012年10月17日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2013年1月16日 | Group: Database references |
---|
改定 1.2 | 2023年6月14日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Other カテゴリ: database_2 / pdbx_database_status ...database_2 / pdbx_database_status / pdbx_nmr_spectrometer / pdbx_struct_conn_angle / struct_conn / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_nmr_data / _pdbx_nmr_spectrometer.model / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
---|
改定 1.3 | 2024年5月15日 | Group: Data collection / Database references / カテゴリ: chem_comp_atom / chem_comp_bond / database_2 / Item: _database_2.pdbx_DOI |
---|
|
---|