- PDB-2l42: The solution structure of Rap1 BRCT domain from Saccharomyces cer... -
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Basic information
Entry
Database: PDB / ID: 2l42
Title
The solution structure of Rap1 BRCT domain from Saccharomyces cerevisiae
Components
DNA-binding protein RAP1
Keywords
PROTEIN BINDING / Rap1 / BRCT domain / DNA BINDING PROTEIN
Function / homology
Function and homology information
positive regulation of ribosomal protein gene transcription by RNA polymerase II / G-quadruplex DNA formation / protection from non-homologous end joining at telomere / establishment of protein localization to telomere / establishment of protein localization to chromatin / telomere maintenance via telomere lengthening / shelterin complex / G-quadruplex DNA binding / double-stranded telomeric DNA binding / silent mating-type cassette heterochromatin formation ...positive regulation of ribosomal protein gene transcription by RNA polymerase II / G-quadruplex DNA formation / protection from non-homologous end joining at telomere / establishment of protein localization to telomere / establishment of protein localization to chromatin / telomere maintenance via telomere lengthening / shelterin complex / G-quadruplex DNA binding / double-stranded telomeric DNA binding / silent mating-type cassette heterochromatin formation / regulation of glycolytic process / DNA binding, bending / nuclear chromosome / telomeric DNA binding / TFIID-class transcription factor complex binding / subtelomeric heterochromatin formation / cis-regulatory region sequence-specific DNA binding / nucleosomal DNA binding / TBP-class protein binding / telomere maintenance / protein-DNA complex / histone binding / RNA polymerase II-specific DNA-binding transcription factor binding / transcription regulator complex / sequence-specific DNA binding / chromosome, telomeric region / DNA-binding transcription factor activity, RNA polymerase II-specific / DNA-binding transcription factor activity / regulation of DNA-templated transcription / negative regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / nucleus / cytosol Similarity search - Function
Type: Bruker DMX / Manufacturer: Bruker / Model: DMX / Field strength: 500 MHz
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Processing
NMR software
Name
Developer
Classification
CNS
Brunger, Adams, Clore, Gros, NilgesandRead
chemicalshiftcalculation
CNS
Brunger, Adams, Clore, Gros, NilgesandRead
dataanalysis
Sparky
Goddard
collection
Sparky
Goddard
chemicalshiftassignment
CNS
Brunger, Adams, Clore, Gros, NilgesandRead
refinement
Refinement
Method: simulated annealing / Software ordinal: 1
NMR representative
Selection criteria: closest to the average
NMR ensemble
Conformer selection criteria: structures with the lowest energy Conformers calculated total number: 150 / Conformers submitted total number: 20 / Representative conformer: 1
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