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- PDB-2kyo: Dimeric human ckit-2 proto-oncogene promoter quadruplex DNA NMR, ... -
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Open data
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Basic information
Entry | Database: PDB / ID: 2kyo | ||||||||||||||||||||
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Title | Dimeric human ckit-2 proto-oncogene promoter quadruplex DNA NMR, 10 structures | ||||||||||||||||||||
![]() | 5'-D(*![]() DNA / G-tetrad / all-parallel quadruplex / intergenic recombination | Function / homology | DNA / DNA (> 10) | ![]() Method | SOLUTION NMR / torsion angle dynamics | Model details | lowest energy, model 1 | ![]() Kuryavyi, V. / Phan, A.T. / Patel, D.J. | ![]() ![]() Title: Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter. Authors: Kuryavyi, V. / Phan, A.T. / Patel, D.J. History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 287.9 KB | Display | ![]() |
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PDB format | ![]() | 245.2 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
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-Validation report
Summary document | ![]() | 297.4 KB | Display | ![]() |
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Full document | ![]() | 370 KB | Display | |
Data in XML | ![]() | 4.3 KB | Display | |
Data in CIF | ![]() | 8.5 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
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Links
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Assembly
Deposited unit | ![]()
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NMR ensembles |
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Components
#1: DNA chain | Mass: 6651.258 Da / Num. of mol.: 2 / Source method: obtained synthetically |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||||||||||||||||||
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NMR experiment |
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Sample preparation
Details |
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Sample |
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Sample conditions | Ionic strength: 100 / pH: 6.8 / Pressure: 1 atm / Temperature: 298 K |
-NMR measurement
NMR spectrometer | Type: VARIAN INOVA / Manufacturer: Varian / Model: INOVA / Field strength: 600 MHz |
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Processing
NMR software |
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Refinement | Method: torsion angle dynamics / Software ordinal: 1 | ||||||||||||||||
NMR representative | Selection criteria: lowest energy | ||||||||||||||||
NMR ensemble | Conformer selection criteria: structures with the lowest energy Conformers calculated total number: 100 / Conformers submitted total number: 10 |