登録情報 | データベース: PDB / ID: 2jx0 |
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タイトル | The paxillin-binding domain (PBD) of G Protein Coupled Receptor (GPCR)-kinase (GRK) interacting protein 1 (GIT1) |
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要素 | ARF GTPase-activating protein GIT1 |
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キーワード | CELL ADHESION / SIGNALING PROTEIN / paxillin binding domain homologue / ANK repeat / Cytoplasm / GTPase activation / Metal-binding / Phosphorylation / Zinc / Zinc-finger |
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機能・相同性 | 機能・相同性情報
negative regulation of ARF protein signal transduction / structural constituent of postsynaptic specialization / RAC2 GTPase cycle / Ephrin signaling / RHOU GTPase cycle / RHOV GTPase cycle / RHOQ GTPase cycle / RAC1 GTPase cycle / motor learning / synaptic vesicle recycling ...negative regulation of ARF protein signal transduction / structural constituent of postsynaptic specialization / RAC2 GTPase cycle / Ephrin signaling / RHOU GTPase cycle / RHOV GTPase cycle / RHOQ GTPase cycle / RAC1 GTPase cycle / motor learning / synaptic vesicle recycling / negative regulation of inflammatory response to wounding / inhibitory synapse / intramembranous ossification / immunological synapse formation / positive regulation of microtubule nucleation / dendritic spine development / regulation of G protein-coupled receptor signaling pathway / regulation of ARF protein signal transduction / gamma-tubulin binding / negative regulation of glycolytic process / negative regulation of interleukin-1 beta production / neurotransmitter receptor localization to postsynaptic specialization membrane / regulation of synaptic vesicle exocytosis / positive regulation of receptor catabolic process / mitotic spindle pole / calyx of Held / excitatory synapse / ephrin receptor signaling pathway / GABA-ergic synapse / neuron development / cellular response to epidermal growth factor stimulus / presynaptic modulation of chemical synaptic transmission / GTPase activator activity / protein tyrosine kinase binding / cell redox homeostasis / regulation of cytokinesis / locomotory behavior / brain development / small GTPase binding / lamellipodium / growth cone / scaffold protein binding / cellular response to lipopolysaccharide / protein phosphatase binding / postsynapse / postsynaptic density / endosome / neuron projection / focal adhesion / centrosome / glutamatergic synapse / synapse / dendrite / protein-containing complex binding / identical protein binding / metal ion binding / cytosol類似検索 - 分子機能 : / Arf GTPase-activating protein GIT1/2, coiled-coil domain / GIT coiled-coil Rho guanine nucleotide exchange factor / ARF GTPase-activating protein GIT1, C-terminal / G protein-coupled receptor kinase-interacting protein 1 C term / GIT, Spa2 homology (SHD) domain / Spa2 homology domain (SHD) of GIT / Helical motif in the GIT family of ADP-ribosylation factor GTPase-activating proteins / Arf GTPase activating protein / ArfGAP domain superfamily ...: / Arf GTPase-activating protein GIT1/2, coiled-coil domain / GIT coiled-coil Rho guanine nucleotide exchange factor / ARF GTPase-activating protein GIT1, C-terminal / G protein-coupled receptor kinase-interacting protein 1 C term / GIT, Spa2 homology (SHD) domain / Spa2 homology domain (SHD) of GIT / Helical motif in the GIT family of ADP-ribosylation factor GTPase-activating proteins / Arf GTPase activating protein / ArfGAP domain superfamily / Putative GTPase activating protein for Arf / ARF GTPase-activating proteins domain profile. / Putative GTP-ase activating proteins for the small GTPase, ARF / Nucleotidyltransferases domain 2 / ARFGAP/RecO-like zinc finger / Four Helix Bundle (Hemerythrin (Met), subunit A) / Ankyrin repeats (3 copies) / Ankyrin repeat profile. / Ankyrin repeat region circular profile. / ankyrin repeats / Ankyrin repeat / Ankyrin repeat-containing domain superfamily / Up-down Bundle / Mainly Alpha類似検索 - ドメイン・相同性 |
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生物種 | ![](img/tx_mammal.gif) Rattus norvegicus (ドブネズミ) |
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手法 | 溶液NMR / torsion angle dynamics |
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データ登録者 | Zhang, Z. / Guibao, C.D. / Simmerman, J.A. / Zheng, J. |
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引用 | ジャーナル: J.Biol.Chem. / 年: 2008 タイトル: GIT1 paxillin-binding domain is a four-helix bundle, and it binds to both paxillin LD2 and LD4 motifs. 著者: Zhang, Z.M. / Simmerman, J.A. / Guibao, C.D. / Zheng, J.J. |
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履歴 | 登録 | 2007年11月1日 | 登録サイト: BMRB / 処理サイト: RCSB |
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改定 1.0 | 2008年4月29日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Version format compliance |
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改定 1.2 | 2022年3月16日 | Group: Data collection / Database references / Derived calculations カテゴリ: database_2 / pdbx_nmr_spectrometer ...database_2 / pdbx_nmr_spectrometer / pdbx_struct_assembly / pdbx_struct_oper_list / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_nmr_spectrometer.model / _struct_ref_seq_dif.details |
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改定 1.3 | 2024年5月29日 | Group: Data collection / カテゴリ: chem_comp_atom / chem_comp_bond |
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