+Open data
-Basic information
Entry | Database: PDB / ID: 2jtd | ||||||
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Title | Skelemin Immunoglobulin C2 like domain 4 | ||||||
Components | Myomesin-1 | ||||||
Keywords | CELL ADHESION / Skelemin / Immunoglobulin domain / Muscle protein / Thick filament / IMMUNE SYSTEM | ||||||
Function / homology | Function and homology information extraocular skeletal muscle development / myosin filament / M band / protein kinase A signaling / sarcomere / muscle contraction / positive regulation of protein secretion / structural constituent of cytoskeleton / kinase binding / cytoskeleton ...extraocular skeletal muscle development / myosin filament / M band / protein kinase A signaling / sarcomere / muscle contraction / positive regulation of protein secretion / structural constituent of cytoskeleton / kinase binding / cytoskeleton / positive regulation of gene expression / protein homodimerization activity / identical protein binding Similarity search - Function | ||||||
Biological species | Mus musculus (house mouse) | ||||||
Method | SOLUTION NMR / Refinement in Explicit Solvent | ||||||
Authors | Deshmukh, L. / Vinogradova, O. | ||||||
Citation | Journal: J.Biol.Chem. / Year: 2007 Title: Structural insight into the interaction between platelet integrin alphaIIbbeta3 and cytoskeletal protein skelemin. Authors: Deshmukh, L. / Tyukhtenko, S. / Liu, J. / Fox, J.E. / Qin, J. / Vinogradova, O. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 2jtd.cif.gz | 896.4 KB | Display | PDBx/mmCIF format |
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PDB format | pdb2jtd.ent.gz | 778 KB | Display | PDB format |
PDBx/mmJSON format | 2jtd.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/jt/2jtd ftp://data.pdbj.org/pub/pdb/validation_reports/jt/2jtd | HTTPS FTP |
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-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein | Mass: 16397.605 Da / Num. of mol.: 1 / Fragment: residues:1207-1328 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Mus musculus (house mouse) / Gene: Myom1 / Production host: Escherichia coli (E. coli) / References: UniProt: Q62234 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||||||||||||||||||||||||||
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NMR experiment |
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-Sample preparation
Details | Contents: 2.7 mM potassium chloride, 140 mM sodium chloride, 10 mM sodium phosphate, 1.8 mM potassium phosphate, 95% H2O/5% D2O Solvent system: 95% H2O/5% D2O | |||||||||||||||
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Sample |
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Sample conditions | Ionic strength: 1 / pH: 7.2 / Pressure: ambient / Temperature: 313 K |
-NMR measurement
NMR spectrometer |
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-Processing
NMR software |
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Refinement | Method: Refinement in Explicit Solvent / Software ordinal: 1 Details: Linge et al,Proteins:Structure, Function and Genetics 50:496-506(2003) | ||||||||||||
NMR representative | Selection criteria: lowest energy | ||||||||||||
NMR ensemble | Conformer selection criteria: structures with the lowest energy Conformers calculated total number: 60 / Conformers submitted total number: 20 |