- PDB-2j63: Crystal structure of AP endonuclease LMAP from Leishmania major -
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Basic information
Entry
Database: PDB / ID: 2j63
Title
Crystal structure of AP endonuclease LMAP from Leishmania major
Components
AP-ENDONUCLEASE
Keywords
LYASE / LEISHMANIA / ENDONUCLEASE / BASE EXCISION REPAIR
Function / homology
Function and homology information
double-stranded DNA 3'-5' DNA exonuclease activity / phosphodiesterase I activity / DNA-(apurinic or apyrimidinic site) endonuclease activity / base-excision repair / endonuclease activity / Hydrolases; Acting on ester bonds / lyase activity / DNA repair / DNA binding / nucleus / metal ion binding Similarity search - Function
AP endonuclease 1, conserved site / AP endonucleases family 1 signature 3. / AP endonuclease 1, binding site / AP endonucleases family 1 signature 1. / AP endonuclease 1 / AP endonucleases family 1 profile. / Deoxyribonuclease I; Chain A / Endonuclease/exonuclease/phosphatase / Endonuclease/exonuclease/phosphatase / Endonuclease/Exonuclease/phosphatase family ...AP endonuclease 1, conserved site / AP endonucleases family 1 signature 3. / AP endonuclease 1, binding site / AP endonucleases family 1 signature 1. / AP endonuclease 1 / AP endonucleases family 1 profile. / Deoxyribonuclease I; Chain A / Endonuclease/exonuclease/phosphatase / Endonuclease/exonuclease/phosphatase / Endonuclease/Exonuclease/phosphatase family / Endonuclease/exonuclease/phosphatase superfamily / 4-Layer Sandwich / Alpha Beta Similarity search - Domain/homology
Component-ID: 1 / Ens-ID: 1 / Beg auth comp-ID: ILE / Beg label comp-ID: ILE / End auth comp-ID: HIS / End label comp-ID: HIS / Refine code: 2 / Auth seq-ID: 90 - 446 / Label seq-ID: 110 - 466
Dom-ID
Auth asym-ID
Label asym-ID
1
A
A
2
B
B
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Components
#1: Protein
AP-ENDONUCLEASE / APURINIC/APYRIMIDINIC ENDONUCLEASE-REDOX PROTEIN / LMAP
Mass: 50866.961 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) LEISHMANIA MAJOR (eukaryote) / Strain: 252 / Description: ISOLATED IN IRAN AND PROVIDED BY S. MESHNIK / Plasmid: PET-28A / Production host: ESCHERICHIA COLI (E. coli) / Strain (production host): BL21(DE3) References: UniProt: O15922, DNA-(apurinic or apyrimidinic site) lyase