chemokine (C-C motif) ligand 11 production / memory T cell activation / T-helper 2 cell activation / response to nitrogen dioxide / positive regulation of CD4-positive, alpha-beta T cell costimulation / positive regulation of interleukin-4-dependent isotype switching to IgE isotypes / positive regulation of immunoglobulin production => GO:0002639 / defense response to nematode / positive regulation of CD4-positive, alpha-beta T cell differentiation / positive regulation of immunoglobulin mediated immune response ...chemokine (C-C motif) ligand 11 production / memory T cell activation / T-helper 2 cell activation / response to nitrogen dioxide / positive regulation of CD4-positive, alpha-beta T cell costimulation / positive regulation of interleukin-4-dependent isotype switching to IgE isotypes / positive regulation of immunoglobulin production => GO:0002639 / defense response to nematode / positive regulation of CD4-positive, alpha-beta T cell differentiation / positive regulation of immunoglobulin mediated immune response / regulation of adaptive immune response / negative regulation of T-helper 1 cell differentiation / tumor necrosis factor receptor superfamily binding / tumor necrosis factor receptor activity / negative regulation of regulatory T cell differentiation / positive regulation of T-helper 2 cell differentiation / TNFs bind their physiological receptors / acute inflammatory response / positive regulation of alpha-beta T cell proliferation / positive regulation of B cell activation / positive regulation of type 2 immune response / positive regulation of interleukin-13 production / positive regulation of memory T cell differentiation / negative regulation of interleukin-17 production / tumor necrosis factor receptor binding / positive regulation of immunoglobulin production / positive regulation of interleukin-4 production / plasma membrane => GO:0005886 / positive regulation of interleukin-10 production / negative regulation of type II interferon production / T cell proliferation / positive regulation of T cell proliferation / positive regulation of B cell proliferation / tumor necrosis factor-mediated signaling pathway / positive regulation of interleukin-12 production / positive regulation of cytokine production / cytokine activity / response to virus / negative regulation of DNA-binding transcription factor activity / positive regulation of T cell cytokine production / positive regulation of inflammatory response / cellular response to prostaglandin E stimulus / positive regulation of interleukin-6 production / positive regulation of type II interferon production / virus receptor activity / regulation of inflammatory response / cellular response to lipopolysaccharide / inflammatory response / immune response / external side of plasma membrane / signaling receptor binding / negative regulation of DNA-templated transcription / positive regulation of cell population proliferation / cell surface / signal transduction / extracellular space / plasma membrane 類似検索 - 分子機能
The crystallographic assymmetric unit consists of one ligand protomer and one receptor protomer. A crystallographic 3-fold axis generates the biologically relevant trimer