登録情報 | データベース: PDB / ID: 2ftu |
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タイトル | solution structure of domain 3 of RAP |
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要素 | Alpha-2-macroglobulin receptor-associated protein, domain 3 |
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キーワード | LIPID BINDING PROTEIN / domain 3 / RAP / receptor-associated protein |
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機能・相同性 | 機能・相同性情報
extracellular negative regulation of signal transduction / lipase binding / negative regulation of very-low-density lipoprotein particle clearance / regulation of receptor-mediated endocytosis / rough endoplasmic reticulum lumen / receptor antagonist activity / amyloid-beta clearance by transcytosis / negative regulation of amyloid-beta clearance / very-low-density lipoprotein particle receptor binding / negative regulation of receptor internalization ...extracellular negative regulation of signal transduction / lipase binding / negative regulation of very-low-density lipoprotein particle clearance / regulation of receptor-mediated endocytosis / rough endoplasmic reticulum lumen / receptor antagonist activity / amyloid-beta clearance by transcytosis / negative regulation of amyloid-beta clearance / very-low-density lipoprotein particle receptor binding / negative regulation of receptor internalization / positive regulation of amyloid-beta clearance / cis-Golgi network / low-density lipoprotein particle receptor binding / endoplasmic reticulum-Golgi intermediate compartment / endomembrane system / negative regulation of protein binding / endosome lumen / Golgi lumen / heparin binding / amyloid-beta binding / receptor ligand activity / endosome / signaling receptor binding / Golgi apparatus / cell surface / signal transduction / endoplasmic reticulum / extracellular region / plasma membrane類似検索 - 分子機能 RAP domain / Receptor-associated Protein / Alpha-2-macroglobulin receptor-associated protein, domain 1 / Alpha-2-macroglobulin RAP, C-terminal / RAP domain superfamily / Alpha-2-macroglobulin RAP, domain 3 / Alpha-2-macroglobulin RAP, domain 2 / Alpha-2-macroglobulin receptor-associated protein / Alpha-2-macroglobulin RAP, N-terminal domain / Alpha-2-macroglobulin RAP, C-terminal domain ...RAP domain / Receptor-associated Protein / Alpha-2-macroglobulin receptor-associated protein, domain 1 / Alpha-2-macroglobulin RAP, C-terminal / RAP domain superfamily / Alpha-2-macroglobulin RAP, domain 3 / Alpha-2-macroglobulin RAP, domain 2 / Alpha-2-macroglobulin receptor-associated protein / Alpha-2-macroglobulin RAP, N-terminal domain / Alpha-2-macroglobulin RAP, C-terminal domain / Endoplasmic reticulum targeting sequence. / Up-down Bundle / Mainly Alpha類似検索 - ドメイン・相同性 Alpha-2-macroglobulin receptor-associated protein類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | 溶液NMR / torsion angle dynamics |
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データ登録者 | Lee, D. / Walsh, J.D. / Wang, Y.-X. |
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引用 | ジャーナル: Mol.Cell / 年: 2006 タイトル: RAP uses a histidine switch to regulate its interaction with LRP in the ER and Golgi. 著者: Lee, D. / Walsh, J.D. / Mikhailenko, I. / Yu, P. / Migliorini, M. / Wu, Y. / Krueger, S. / Curtis, J.E. / Harris, B. / Lockett, S. / Blacklow, S.C. / Strickland, D.K. / Wang, Y.X. |
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履歴 | 登録 | 2006年1月24日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2006年5月9日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年5月1日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2022年3月9日 | Group: Database references / Derived calculations カテゴリ: database_2 / pdbx_struct_assembly / pdbx_struct_oper_list Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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改定 1.4 | 2024年5月29日 | Group: Data collection / カテゴリ: chem_comp_atom / chem_comp_bond |
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