登録情報 データベース : PDB / ID : 2eqr 構造の表示 ダウンロードとリンクタイトル Solution structure of the first SANT domain from human nuclear receptor corepressor 1 要素Nuclear receptor corepressor 1 詳細 キーワード TRANSCRIPTION / Sant domain / Nuclear receptor corepressor 1 / N-CoR1 / N-CoR / Structural Genomics / NPPSFA / National Project on Protein Structural and Functional Analyses / RIKEN Structural Genomics/Proteomics Initiative / RSGI機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
NR1D1 (REV-ERBA) represses gene expression / Loss of MECP2 binding ability to the NCoR/SMRT complex / negative regulation of androgen receptor signaling pathway / negative regulation of JNK cascade / negative regulation of glycolytic process / nuclear thyroid hormone receptor binding / negative regulation of fatty acid metabolic process / NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis / Notch-HLH transcription pathway / locomotor rhythm ... NR1D1 (REV-ERBA) represses gene expression / Loss of MECP2 binding ability to the NCoR/SMRT complex / negative regulation of androgen receptor signaling pathway / negative regulation of JNK cascade / negative regulation of glycolytic process / nuclear thyroid hormone receptor binding / negative regulation of fatty acid metabolic process / NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis / Notch-HLH transcription pathway / locomotor rhythm / histone deacetylase complex / Regulation of MECP2 expression and activity / spindle assembly / Nuclear signaling by ERBB4 / NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux / transcription repressor complex / Regulation of lipid metabolism by PPARalpha / negative regulation of miRNA transcription / nuclear receptor binding / HDACs deacetylate histones / Downregulation of SMAD2/3:SMAD4 transcriptional activity / Heme signaling / Transcriptional activation of mitochondrial biogenesis / PPARA activates gene expression / Cytoprotection by HMOX1 / NOTCH1 Intracellular Domain Regulates Transcription / mitotic spindle / histone deacetylase binding / Constitutive Signaling by NOTCH1 PEST Domain Mutants / Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants / Transcriptional regulation of white adipocyte differentiation / Nuclear Receptor transcription pathway / Activation of anterior HOX genes in hindbrain development during early embryogenesis / HCMV Early Events / transcription corepressor activity / Circadian Clock / chromatin organization / RNA polymerase II-specific DNA-binding transcription factor binding / transcription cis-regulatory region binding / negative regulation of DNA-templated transcription / chromatin / negative regulation of transcription by RNA polymerase II / nucleoplasm / membrane / nucleus / cytosol 類似検索 - 分子機能 N-CoR, GPS2-interacting domain / : / G-protein pathway suppressor 2-interacting domain / SANT domain profile. / SANT domain / Myb domain / Myb-like DNA-binding domain / SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains / SANT/Myb domain / Homeodomain-like ... N-CoR, GPS2-interacting domain / : / G-protein pathway suppressor 2-interacting domain / SANT domain profile. / SANT domain / Myb domain / Myb-like DNA-binding domain / SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains / SANT/Myb domain / Homeodomain-like / Homeobox-like domain superfamily / Arc Repressor Mutant, subunit A / Orthogonal Bundle / Mainly Alpha 類似検索 - ドメイン・相同性生物種 Homo sapiens (ヒト)手法 溶液NMR / torsion angle dynamics 詳細データ登録者 Zhang, H.P. / Hayahsi, F. / Yokoyama, S. / RIKEN Structural Genomics/Proteomics Initiative (RSGI) 引用ジャーナル : To be Published タイトル : Solution structure of the first SANT domain from human nuclear receptor corepressor 1著者 : Zhang, H.P. / Hayashi, F. / Yokoyama, S. 履歴 登録 2007年3月30日 登録サイト : PDBJ / 処理サイト : PDBJ改定 1.0 2008年4月1日 Provider : repository / タイプ : Initial release改定 1.1 2011年7月13日 Group : Version format compliance改定 1.2 2022年3月9日 Group : Data collection / Database references / Derived calculationsカテゴリ : database_2 / pdbx_nmr_software ... database_2 / pdbx_nmr_software / pdbx_struct_assembly / pdbx_struct_oper_list / struct_ref_seq_dif Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_nmr_software.name / _struct_ref_seq_dif.details 改定 1.3 2024年5月29日 Group : Data collection / カテゴリ : chem_comp_atom / chem_comp_bond
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