- PDB-2d6m: Crystal structure of mouse galectin-9 N-terminal CRD in complex w... -
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IDまたはキーワード:
読み込み中...
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基本情報
登録情報
データベース: PDB / ID: 2d6m
タイトル
Crystal structure of mouse galectin-9 N-terminal CRD in complex with lactose
要素
lectin, galactose binding, soluble 9
キーワード
SUGAR BINDING PROTEIN / beta sandwich / carbohydrate binding protein / galectin / Structural Genomics
機能・相同性
機能・相同性情報
regulation of natural killer cell differentiation / negative regulation of natural killer cell degranulation / negative regulation of natural killer cell activation / positive regulation of defense response to bacterium / positive regulation of oxidoreductase activity / maintenance of protein location / positive regulation of interleukin-1 production / galactoside binding / negative regulation of CD4-positive, alpha-beta T cell proliferation / positive regulation of regulatory T cell differentiation ...regulation of natural killer cell differentiation / negative regulation of natural killer cell degranulation / negative regulation of natural killer cell activation / positive regulation of defense response to bacterium / positive regulation of oxidoreductase activity / maintenance of protein location / positive regulation of interleukin-1 production / galactoside binding / negative regulation of CD4-positive, alpha-beta T cell proliferation / positive regulation of regulatory T cell differentiation / positive regulation of innate immune response / positive regulation of macrophage activation / heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules / immune system process / receptor clustering / positive regulation of SMAD protein signal transduction / positive regulation of interleukin-10 production / negative regulation of type II interferon production / positive regulation of T cell migration / positive regulation of chemokine production / protein serine/threonine kinase activator activity / transforming growth factor beta receptor signaling pathway / positive regulation of cytokine production / female pregnancy / cellular response to virus / negative regulation of inflammatory response / positive regulation of interleukin-6 production / chemotaxis / positive regulation of tumor necrosis factor production / carbohydrate binding / collagen-containing extracellular matrix / response to lipopolysaccharide / negative regulation of gene expression / signaling receptor binding / positive regulation of gene expression / enzyme binding / extracellular region / nucleus / plasma membrane / cytoplasm / cytosol 類似検索 - 分子機能
解像度: 1.6→49.39 Å / Cor.coef. Fo:Fc: 0.956 / Cor.coef. Fo:Fc free: 0.922 / SU B: 2.198 / SU ML: 0.078 / 交差検証法: THROUGHOUT / ESU R: 0.111 / ESU R Free: 0.114 / 立体化学のターゲット値: MAXIMUM LIKELIHOOD / 詳細: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
Rfactor
反射数
%反射
Selection details
Rfree
0.23197
1958
5.1 %
RANDOM
Rwork
0.18255
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-
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obs
0.18513
36422
93.52 %
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溶媒の処理
イオンプローブ半径: 0.8 Å / 減衰半径: 0.8 Å / VDWプローブ半径: 1.2 Å / 溶媒モデル: MASK