Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB / monoamine oxidase activity / monoamine oxidase / phenylethylamine catabolic process / positive regulation of dopamine metabolic process / response to aluminum ion / negative regulation of serotonin secretion / response to selenium ion / primary-amine oxidase / aliphatic amine oxidase activity ...Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB / monoamine oxidase activity / monoamine oxidase / phenylethylamine catabolic process / positive regulation of dopamine metabolic process / response to aluminum ion / negative regulation of serotonin secretion / response to selenium ion / primary-amine oxidase / aliphatic amine oxidase activity / dopamine catabolic process / primary methylamine oxidase activity / mitochondrial envelope / hydrogen peroxide biosynthetic process / response to corticosterone / substantia nigra development / response to toxic substance / flavin adenine dinucleotide binding / response to ethanol / mitochondrial outer membrane / response to lipopolysaccharide / electron transfer activity / response to xenobiotic stimulus / neuronal cell body / dendrite / mitochondrion / identical protein binding 類似検索 - 分子機能
ENGINEERED RESIDUE IN CHAIN A, TYR 434 TO TRP ENGINEERED RESIDUE IN CHAIN B, TYR 434 TO TRP THE ...ENGINEERED RESIDUE IN CHAIN A, TYR 434 TO TRP ENGINEERED RESIDUE IN CHAIN B, TYR 434 TO TRP THE MUTATED RESIDUE IS NUMBERED 435 IN THE COORDINATE RECORDS BELOW.
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実験情報
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実験
実験
手法: X線回折 / 使用した結晶の数: 1
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試料調製
結晶
マシュー密度: 2.52 Å3/Da / 溶媒含有率: 50.8 %
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データ収集
回折
平均測定温度: 100 K
放射光源
由来: シンクロトロン / サイト: SLS / ビームライン: X06SA / 波長: 0.95
検出器
タイプ: MARRESEARCH / 検出器: CCD
放射
プロトコル: SINGLE WAVELENGTH / 単色(M)・ラウエ(L): M / 散乱光タイプ: x-ray
放射波長
波長: 0.95 Å / 相対比: 1
反射
解像度: 1.7→15 Å / Num. obs: 136583 / % possible obs: 98.9 % / 冗長度: 3.1 % / Rmerge(I) obs: 0.09 / Net I/σ(I): 10
解像度: 1.7→15 Å / Cor.coef. Fo:Fc: 0.95 / Cor.coef. Fo:Fc free: 0.937 / SU B: 1.91 / SU ML: 0.064 / 交差検証法: THROUGHOUT / ESU R: 0.1 / ESU R Free: 0.095 / 立体化学のターゲット値: MAXIMUM LIKELIHOOD / 詳細: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS.
Rfactor
反射数
%反射
Selection details
Rfree
0.213
3485
2.6 %
RANDOM
Rwork
0.191
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obs
0.191
132929
98.5 %
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溶媒の処理
イオンプローブ半径: 0.8 Å / 減衰半径: 0.8 Å / VDWプローブ半径: 1.2 Å / 溶媒モデル: BABINET MODEL WITH MASK