Entry Database : PDB / ID : 2bju Structure visualization Downloads & linksTitle Plasmepsin II complexed with a highly active achiral inhibitor ComponentsPLASMEPSIN II Details Keywords HYDROLASE / PLASMEPSIN / ASPARTIC PROTEINASE / DRUG DESIGN / MALARIA / ASPARTYL PROTEASE / GLYCOPROTEIN / ZYMOGENFunction / homology Function and homology informationFunction Domain/homology Component
cytostome / plasmepsin II / acquisition of nutrients from host / vacuolar lumen / food vacuole / vacuolar membrane / aspartic-type endopeptidase activity / proteolysis Similarity search - Function Pepsin-like domain / Eukaryotic aspartyl protease / Aspartic peptidase A1 family / Peptidase family A1 domain / Peptidase family A1 domain profile. / Cathepsin D, subunit A; domain 1 / Acid Proteases / Aspartic peptidase, active site / Eukaryotic and viral aspartyl proteases active site. / Aspartic peptidase domain superfamily ... Pepsin-like domain / Eukaryotic aspartyl protease / Aspartic peptidase A1 family / Peptidase family A1 domain / Peptidase family A1 domain profile. / Cathepsin D, subunit A; domain 1 / Acid Proteases / Aspartic peptidase, active site / Eukaryotic and viral aspartyl proteases active site. / Aspartic peptidase domain superfamily / Beta Barrel / Mainly Beta Similarity search - Domain/homologyBiological species PLASMODIUM FALCIPARUM (malaria parasite P. falciparum)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 1.56 Å DetailsAuthors Prade, L. / Jones, A.F. / Boss, C. / Richards-Bildstein, S. / Meyer, S. / Binkert, C. / Bur, D. CitationJournal : J.Biol.Chem. / Year : 2005Title : X-Ray Structure of Plasmepsin II Complexed with a Potent Achiral Inhibitor.Authors : Prade, L. / Jones, A.F. / Boss, C. / Richard-Bildstein, S. / Meyer, S. / Binkert, C. / Bur, D. History Deposition Feb 8, 2005 Deposition site : PDBE / Processing site : PDBERevision 1.0 Apr 18, 2005 Provider : repository / Type : Initial releaseRevision 1.1 May 8, 2011 Group : Version format complianceRevision 1.2 Jul 13, 2011 Group : Version format compliance
Show all Show less Remark 700 SHEET THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN ORDER TO REPRESENT THIS FEATURE IN ... SHEET THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN ORDER TO REPRESENT THIS FEATURE IN THE SHEET RECORDS BELOW, TWO SHEETS ARE DEFINED.