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TitleX-Ray Structure of Plasmepsin II Complexed with a Potent Achiral Inhibitor.
Journal, issue, pagesJ. Biol. Chem., Vol. 280, Page 23837-, Year 2005
Publish dateFeb 8, 2005 (structure data deposition date)
AuthorsPrade, L. / Jones, A.F. / Boss, C. / Richard-Bildstein, S. / Meyer, S. / Binkert, C. / Bur, D.
External linksJ. Biol. Chem. / PubMed:15840589
MethodsX-ray diffraction
Resolution1.56 Å
Structure data

PDB-2bju:
Plasmepsin II complexed with a highly active achiral inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.56 Å

Chemicals

ChemComp-IH4:
N-(R-CARBOXY-ETHYL)-ALPHA-(S)-(2-PHENYLETHYL)

ChemComp-HOH:
WATER

Source
  • plasmodium falciparum (malaria parasite P. falciparum)
KeywordsHYDROLASE / PLASMEPSIN / ASPARTIC PROTEINASE / DRUG DESIGN / MALARIA / ASPARTYL PROTEASE / GLYCOPROTEIN / ZYMOGEN

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