Entry | Database: PDB / ID: 2bep |
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Title | Crystal structure of ubiquitin conjugating enzyme E2-25K |
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Components | UBIQUITIN-CONJUGATING ENZYME E2-25 KDA |
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Keywords | LIGASE / UBIQUITIN / E2 CONJUGATING ENZYME / PROTEIN DEGRADATION / STRUCTURAL PROTEOMICS IN EUROPE / SPINE / STRUCTURAL GENOMICS |
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Function / homology | Function and homology information
Synthesis of active ubiquitin: roles of E1 and E2 enzymes / Antigen processing: Ubiquitination & Proteasome degradation / E2 ubiquitin-conjugating enzyme / ubiquitin conjugating enzyme activity / protein K48-linked ubiquitination / protein polyubiquitination / ubiquitin-protein transferase activity / proteasome-mediated ubiquitin-dependent protein catabolic process / ubiquitin protein ligase binding / ATP binding ...Synthesis of active ubiquitin: roles of E1 and E2 enzymes / Antigen processing: Ubiquitination & Proteasome degradation / E2 ubiquitin-conjugating enzyme / ubiquitin conjugating enzyme activity / protein K48-linked ubiquitination / protein polyubiquitination / ubiquitin-protein transferase activity / proteasome-mediated ubiquitin-dependent protein catabolic process / ubiquitin protein ligase binding / ATP binding / nucleus / cytoplasmSimilarity search - Function Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain / UBA/TS-N domain / Ubiquitin Conjugating Enzyme / Ubiquitin Conjugating Enzyme / Ubiquitin associated domain / Ubiquitin-associated domain / Ubiquitin-associated domain (UBA) profile. / UBA-like superfamily / Ubiquitin-conjugating enzyme, active site / Ubiquitin-conjugating (UBC) active site signature. ...Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain / UBA/TS-N domain / Ubiquitin Conjugating Enzyme / Ubiquitin Conjugating Enzyme / Ubiquitin associated domain / Ubiquitin-associated domain / Ubiquitin-associated domain (UBA) profile. / UBA-like superfamily / Ubiquitin-conjugating enzyme, active site / Ubiquitin-conjugating (UBC) active site signature. / Ubiquitin-conjugating enzyme E2, catalytic domain homologues / Ubiquitin-conjugating enzyme E2 / Ubiquitin-conjugating enzyme / Ubiquitin-conjugating (UBC) core domain profile. / Ubiquitin-conjugating enzyme/RWD-like / Roll / Alpha BetaSimilarity search - Domain/homology |
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Biological species | ![](img/tx_mammal.gif) BOS TAURUS (cattle) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 1.8 Å |
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Authors | Pichler, A. / Knipscheer, P. / Oberhofer, E. / Van Dijk, W.J. / Korner, R. / Velgaard Olsen, J. / Jentsch, S. / Melchior, F. / Sixma, T.K. |
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Citation | Journal: Nat.Struct.Mol.Biol. / Year: 2005 Title: Sumo Imodification of the Ubiquitin Conjugating Enzyme E2-25K Authors: Pichler, A. / Knipscheer, P. / Oberhofer, E. / Van Dijk, W.J. / Korner, R. / Velgaard Olsen, J. / Jentsch, S. / Melchior, F. / Sixma, T.K. |
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History | Deposition | Nov 29, 2004 | Deposition site: PDBE / Processing site: PDBE |
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Revision 1.0 | Feb 16, 2005 | Provider: repository / Type: Initial release |
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Revision 1.1 | Jul 13, 2011 | Group: Advisory / Version format compliance |
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Revision 1.2 | Dec 13, 2023 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Other / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / struct_conn Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_conn.pdbx_leaving_atom_flag |
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