登録情報 | データベース: PDB / ID: 1uvu |
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タイトル | BOVINE THROMBIN--BM12.1700 COMPLEX |
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要素 | (THROMBIN) x 2 |
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キーワード | SERINE PROTEASE / HYDROLASE / THROMBIN / BLOOD COAGULATION |
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機能・相同性 | 機能・相同性情報
fibrinogen binding / thrombin / protein polymerization / positive regulation of blood coagulation / acute-phase response / platelet activation / collagen-containing extracellular matrix / serine-type endopeptidase activity / calcium ion binding / proteolysis / extracellular space類似検索 - 分子機能 Prothrombin/thrombin / Thrombin light chain / Thrombin light chain domain superfamily / Thrombin light chain / Kringle domain / Kringle / Kringle, conserved site / Kringle superfamily / Kringle domain signature. / Kringle domain profile. ...Prothrombin/thrombin / Thrombin light chain / Thrombin light chain domain superfamily / Thrombin light chain / Kringle domain / Kringle / Kringle, conserved site / Kringle superfamily / Kringle domain signature. / Kringle domain profile. / Kringle domain / Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain / Gamma-carboxyglutamic acid-rich (GLA) domain / Gamma-carboxyglutamic acid-rich (GLA) domain superfamily / Vitamin K-dependent carboxylation domain. / Gla domain profile. / Domain containing Gla (gamma-carboxyglutamate) residues. / Kringle-like fold / Serine proteases, trypsin family, histidine active site / Serine proteases, trypsin family, serine active site / Peptidase S1A, chymotrypsin family / Serine proteases, trypsin family, histidine active site. / Serine proteases, trypsin domain profile. / Serine proteases, trypsin family, serine active site. / Trypsin-like serine protease / Serine proteases, trypsin domain / Trypsin / Trypsin-like serine proteases / Thrombin, subunit H / Peptidase S1, PA clan, chymotrypsin-like fold / Peptidase S1, PA clan / Beta Barrel / Mainly Beta類似検索 - ドメイン・相同性 |
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生物種 | ![](img/tx_mammal.gif) Bos taurus (ウシ) |
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手法 | X線回折 / 分子置換 / 解像度: 2.8 Å |
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データ登録者 | Engh, R.A. / Huber, R. |
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引用 | ジャーナル: Structure / 年: 1996 タイトル: Enzyme flexibility, solvent and 'weak' interactions characterize thrombin-ligand interactions: implications for drug design. 著者: Engh, R.A. / Brandstetter, H. / Sucher, G. / Eichinger, A. / Baumann, U. / Bode, W. / Huber, R. / Poll, T. / Rudolph, R. / von der Saal, W. |
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履歴 | 登録 | 1996年10月16日 | 処理サイト: BNL |
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改定 1.0 | 1997年11月19日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年3月24日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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