Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor / fatty acid peroxidase activity / negative regulation of hepatic stellate cell activation / oxidoreductase activity, acting on a heme group of donors / Intracellular oxygen transport / nitric oxide catabolic process / negative regulation of collagen biosynthetic process / carbon monoxide binding / negative regulation of fibroblast migration / catalase activity ...Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor / fatty acid peroxidase activity / negative regulation of hepatic stellate cell activation / oxidoreductase activity, acting on a heme group of donors / Intracellular oxygen transport / nitric oxide catabolic process / negative regulation of collagen biosynthetic process / carbon monoxide binding / negative regulation of fibroblast migration / catalase activity / スーパーオキシドディスムターゼ / superoxide dismutase activity / Β酸化 / nitrite reductase activity / 酸化還元酵素; 他の含窒素化合物が電子供与する / 血液 / 酸化還元酵素; 過酸化物を電子受容体にする; ペルオキシダーゼ / eNOS activation / removal of superoxide radicals / peroxidase activity / oxygen carrier activity / oxygen binding / response to oxidative stress / response to hypoxia / oxidoreductase activity / neuron projection / iron ion binding / neuronal cell body / heme binding / 細胞核 / 細胞質基質 / 細胞質 類似検索 - 分子機能
プロトコル: SINGLE WAVELENGTH / 単色(M)・ラウエ(L): M / 散乱光タイプ: x-ray
放射波長
波長: 1.72 Å / 相対比: 1
反射
解像度: 2.6→30 Å / Num. obs: 19995 / % possible obs: 99.5 % / 冗長度: 11 % / Rmerge(I) obs: 0.057 / Net I/σ(I): 35
反射 シェル
解像度: 2.6→2.69 Å / 冗長度: 10 % / Rmerge(I) obs: 0.159 / Mean I/σ(I) obs: 11 / % possible all: 96.6
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解析
ソフトウェア
名称
分類
REFMAC
精密化
DENZO
データ削減
SCALEPACK
データスケーリング
SOLVE
位相決定
精密化
構造決定の手法: 単波長異常分散 / 解像度: 2.59→29.88 Å / SU B: 12.52 / SU ML: 0.277 / 交差検証法: THROUGHOUT / ESU R Free: 0.387 詳細: RESIDUES A1-A17, A172-A190, AND B1- B17, B172-B190 ARE MISSING IN THE MODEL BECAUSE OF POOR DIFFRACTION DATA