- PDB-4b3w: Crystal structure of human cytoglobin H(E7)Q mutant -
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Open data
ID or keywords:
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Basic information
Entry
Database: PDB / ID: 4b3w
Title
Crystal structure of human cytoglobin H(E7)Q mutant
Components
CYTOGLOBIN
Keywords
OXYGEN TRANSPORT / METAL BINDING PROTEIN / HEME HEXACOORDINATION / PROTEIN CAVITY
Function / homology
Function and homology information
Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor / fatty acid peroxidase activity / nitric oxide dioxygenase activity, heme protein as donor / negative regulation of hepatic stellate cell activation / Intracellular oxygen transport / nitric oxide catabolic process / negative regulation of collagen biosynthetic process / carbon monoxide binding / negative regulation of fibroblast migration / catalase activity ...Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor / fatty acid peroxidase activity / nitric oxide dioxygenase activity, heme protein as donor / negative regulation of hepatic stellate cell activation / Intracellular oxygen transport / nitric oxide catabolic process / negative regulation of collagen biosynthetic process / carbon monoxide binding / negative regulation of fibroblast migration / catalase activity / superoxide dismutase / superoxide dismutase activity / fatty acid oxidation / nitrite reductase activity / Oxidoreductases; Acting on other nitrogenous compounds as donors / oxygen transport / Oxidoreductases; Acting on a peroxide as acceptor; Peroxidases / eNOS activation / removal of superoxide radicals / oxygen carrier activity / oxygen binding / peroxidase activity / response to oxidative stress / oxidoreductase activity / response to hypoxia / neuron projection / iron ion binding / neuronal cell body / heme binding / nucleus / cytoplasm / cytosol Similarity search - Function
Resolution: 2.8→57.74 Å / Cor.coef. Fo:Fc: 0.933 / Cor.coef. Fo:Fc free: 0.874 / SU B: 38.861 / SU ML: 0.342 / Cross valid method: THROUGHOUT / ESU R Free: 0.456 / Stereochemistry target values: MAXIMUM LIKELIHOOD Details: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. USING PROCHECK AS IMPLEMENTED IN CCP4 GIVES NO RAMACHANDRAN OUTLIERS.
Rfactor
Num. reflection
% reflection
Selection details
Rfree
0.27727
907
10 %
RANDOM
Rwork
0.20658
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obs
0.21371
8150
99.7 %
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Solvent computation
Ion probe radii: 0.8 Å / Shrinkage radii: 0.8 Å / VDW probe radii: 1.4 Å / Solvent model: MASK