登録情報 データベース : PDB / ID : 1ukx 構造の表示 ダウンロードとリンクタイトル Solution structure of the RWD domain of mouse GCN2 要素GCN2 eIF2alpha kinase 詳細 キーワード TRANSFERASE / eIF2alpha kinase / UBC-like fold / triple beta-turns / structural genomics / RIKEN Structural Genomics/Proteomics Initiative / RSGI機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
regulation of cytoplasmic translational initiation in response to stress / positive regulation of translational initiation in response to starvation / negative regulation of cytoplasmic translational initiation in response to stress / negative regulation of CREB transcription factor activity / regulation of translational initiation by eIF2 alpha phosphorylation / eiF2alpha phosphorylation in response to endoplasmic reticulum stress / eukaryotic initiation factor eIF2 binding / GCN2-mediated signaling / eukaryotic translation initiation factor 2alpha kinase activity / negative regulation of translational initiation in response to stress ... regulation of cytoplasmic translational initiation in response to stress / positive regulation of translational initiation in response to starvation / negative regulation of cytoplasmic translational initiation in response to stress / negative regulation of CREB transcription factor activity / regulation of translational initiation by eIF2 alpha phosphorylation / eiF2alpha phosphorylation in response to endoplasmic reticulum stress / eukaryotic initiation factor eIF2 binding / GCN2-mediated signaling / eukaryotic translation initiation factor 2alpha kinase activity / negative regulation of translational initiation in response to stress / negative regulation by host of viral genome replication / regulation of translational initiation in response to stress / regulation of feeding behavior / T cell activation involved in immune response / positive regulation of adaptive immune response / regulation of translational initiation / cellular response to cold / neuron projection extension / negative regulation of neuron differentiation / long-term memory / cytosolic ribosome / endoplasmic reticulum unfolded protein response / negative regulation of translational initiation / positive regulation of defense response to virus by host / cellular response to amino acid starvation / cellular response to starvation / response to endoplasmic reticulum stress / learning / DNA damage checkpoint signaling / positive regulation of long-term synaptic potentiation / cellular response to UV / defense response to virus / adaptive immune response / viral translation / protein autophosphorylation / tRNA binding / negative regulation of translation / non-specific serine/threonine protein kinase / positive regulation of protein phosphorylation / cell cycle / protein phosphorylation / protein serine kinase activity / protein serine/threonine kinase activity / positive regulation of gene expression / ATP binding / nucleus / cytoplasm / cytosol 類似検索 - 分子機能 eIF-2-alpha kinase Gcn2 / Histidyl tRNA synthetase-related domain / Anticodon binding domain of tRNAs / RWD domain / RWD domain / RWD domain profile. / RWD / Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain / Histidyl-tRNA synthetase / Ubiquitin Conjugating Enzyme ... eIF-2-alpha kinase Gcn2 / Histidyl tRNA synthetase-related domain / Anticodon binding domain of tRNAs / RWD domain / RWD domain / RWD domain profile. / RWD / Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain / Histidyl-tRNA synthetase / Ubiquitin Conjugating Enzyme / Ubiquitin Conjugating Enzyme / Anticodon-binding domain superfamily / Ubiquitin-conjugating enzyme/RWD-like / Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) / Serine/threonine-protein kinase, active site / Serine/Threonine protein kinases active-site signature. / Protein kinase domain / Serine/Threonine protein kinases, catalytic domain / Roll / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / Alpha Beta 類似検索 - ドメイン・相同性生物種 Mus musculus (ハツカネズミ)手法 溶液NMR / torsion angle dynamics , restrained molecular dynamics 詳細データ登録者 Nameki, N. / Yoneyama, M. / Koshiba, S. / Inoue, M. / Kigawa, T. / Yokoyama, S. / RIKEN Structural Genomics/Proteomics Initiative (RSGI) 引用ジャーナル : Protein Sci. / 年 : 2004タイトル : Solution structure of the RWD domain of the mouse GCN2 protein.著者: Nameki, N. / Yoneyama, M. / Koshiba, S. / Tochio, N. / Inoue, M. / Seki, E. / Matsuda, T. / Tomo, Y. / Harada, T. / Saito, K. / Kobayashi, N. / Yabuki, T. / Aoki, M. / Nunokawa, E. / Matsuda, ... 著者 : Nameki, N. / Yoneyama, M. / Koshiba, S. / Tochio, N. / Inoue, M. / Seki, E. / Matsuda, T. / Tomo, Y. / Harada, T. / Saito, K. / Kobayashi, N. / Yabuki, T. / Aoki, M. / Nunokawa, E. / Matsuda, N. / Sakagami, N. / Terada, T. / Shirouzu, M. / Yoshida, M. / Hirota, H. / Osanai, T. / Tanaka, A. / Arakawa, T. / Carninci, P. / Kawai, J. / Hayashizaki, Y. / Kinoshita, K. / Guntert, P. / Kigawa, T. / Yokoyama, S. 履歴 登録 2003年9月3日 登録サイト : PDBJ / 処理サイト : PDBJ改定 1.0 2004年8月3日 Provider : repository / タイプ : Initial release改定 1.1 2008年4月27日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Version format compliance改定 1.3 2022年3月2日 Group : Data collection / Database references / Derived calculationsカテゴリ : database_2 / pdbx_nmr_software ... database_2 / pdbx_nmr_software / pdbx_nmr_spectrometer / pdbx_struct_assembly / pdbx_struct_oper_list / struct_ref_seq_dif Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_nmr_software.name / _pdbx_nmr_spectrometer.model / _struct_ref_seq_dif.details 改定 1.4 2023年12月27日 Group : Data collection / カテゴリ : chem_comp_atom / chem_comp_bond
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