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Open data
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Basic information
Entry | Database: PDB / ID: 1tit | ||||||
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Title | TITIN, IG REPEAT 27, NMR, MINIMIZED AVERAGE STRUCTURE | ||||||
![]() | TITIN, I27 | ||||||
![]() | IMMUNOGLOBULIN-LIKE DOMAIN / MUSCLE PROTEIN | ||||||
Function / homology | ![]() sarcomerogenesis / structural molecule activity conferring elasticity / telethonin binding / skeletal muscle myosin thick filament assembly / cardiac myofibril assembly / muscle alpha-actinin binding / detection of muscle stretch / cardiac muscle tissue morphogenesis / regulation of catalytic activity / cardiac muscle hypertrophy ...sarcomerogenesis / structural molecule activity conferring elasticity / telethonin binding / skeletal muscle myosin thick filament assembly / cardiac myofibril assembly / muscle alpha-actinin binding / detection of muscle stretch / cardiac muscle tissue morphogenesis / regulation of catalytic activity / cardiac muscle hypertrophy / mitotic chromosome condensation / Striated Muscle Contraction / actinin binding / M band / I band / cardiac muscle cell development / regulation of protein kinase activity / structural constituent of muscle / sarcomere organization / skeletal muscle thin filament assembly / striated muscle thin filament / striated muscle contraction / cardiac muscle contraction / protein kinase A signaling / condensed nuclear chromosome / muscle contraction / positive regulation of protein secretion / Z disc / response to calcium ion / : / actin filament binding / Platelet degranulation / protein tyrosine kinase activity / protease binding / non-specific serine/threonine protein kinase / calmodulin binding / phosphorylation / protein serine kinase activity / protein serine/threonine kinase activity / calcium ion binding / positive regulation of gene expression / protein kinase binding / enzyme binding / extracellular exosome / extracellular region / ATP binding / identical protein binding / cytosol Similarity search - Function | ||||||
Biological species | ![]() | ||||||
Method | SOLUTION NMR | ||||||
![]() | Improta, S. / Politou, A.S. / Pastore, A. | ||||||
![]() | ![]() Title: Immunoglobulin-like modules from titin I-band: extensible components of muscle elasticity. Authors: Improta, S. / Politou, A.S. / Pastore, A. #1: ![]() Title: Tertiary Structure of an Immunoglobulin-Like Domain from the Giant Muscle Protein Titin: A New Member of the I Set Authors: Pfuhl, M. / Pastore, A. #2: ![]() Title: Titins: Giant Proteins in Charge of Muscle Ultrastructure and Elasticity Authors: Labeit, S. / Kolmerer, B. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 55.7 KB | Display | ![]() |
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PDB format | ![]() | 28.9 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 242.7 KB | Display | ![]() |
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Full document | ![]() | 242.5 KB | Display | |
Data in XML | ![]() | 5 KB | Display | |
Data in CIF | ![]() | 6 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
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Links
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Assembly
Deposited unit | ![]()
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NMR ensembles |
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Components
#1: Protein | Mass: 10928.426 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Details: SOLUTION STRUCTURE, T=308K, PH 4.5, 10MM ACETATE BUFFER Source: (gene. exp.) ![]() ![]() ![]() |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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Sample preparation
Crystal grow | *PLUS Method: other / Details: NMR |
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Processing
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NMR software | Name: XPLOR (EXTENDED VERSION) / Version: VERSION) / Developer: BRUNGER / Classification: refinement | ||||||||
NMR ensemble | Conformers submitted total number: 1 |