登録情報 データベース : PDB / ID : 1sgh 構造の表示 ダウンロードとリンクタイトル Moesin FERM domain bound to EBP50 C-terminal peptide 要素Ezrin-radixin-moesin binding phosphoprotein 50 Moesin 詳細キーワード STRUCTURAL PROTEIN / FERM-peptide complex機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
import across plasma membrane / regulation of renal phosphate excretion / renal sodium ion transport / type 2 metabotropic glutamate receptor binding / regulation of lymphocyte migration / glutathione transport / T cell aggregation / dopamine receptor binding / renal phosphate ion absorption / gamma-aminobutyric acid transmembrane transporter activity ... import across plasma membrane / regulation of renal phosphate excretion / renal sodium ion transport / type 2 metabotropic glutamate receptor binding / regulation of lymphocyte migration / glutathione transport / T cell aggregation / dopamine receptor binding / renal phosphate ion absorption / gamma-aminobutyric acid transmembrane transporter activity / gamma-aminobutyric acid import / cerebrospinal fluid circulation / regulation of organelle assembly / negative regulation of sodium ion transport / microvillus assembly / T cell migration / positive regulation of early endosome to late endosome transport / membrane to membrane docking / positive regulation of monoatomic ion transmembrane transport / bile acid secretion / maintenance of epithelial cell apical/basal polarity / channel activator activity / uropod / stereocilium tip / plasma membrane organization / intracellular phosphate ion homeostasis / cilium organization / immunological synapse formation / gland morphogenesis / myosin II binding / positive regulation of protein localization to early endosome / phospholipase C-activating dopamine receptor signaling pathway / growth factor receptor binding / establishment of Golgi localization / fibroblast migration / type 3 metabotropic glutamate receptor binding / plasma membrane protein complex / cellular response to testosterone stimulus / establishment of epithelial cell apical/basal polarity / regulation of protein kinase activity / negative regulation of fibroblast migration / establishment of endothelial barrier / chloride channel regulator activity / negative regulation of platelet-derived growth factor receptor signaling pathway / auditory receptor cell stereocilium organization / nuclear migration / positive regulation of podosome assembly / Sensory processing of sound by outer hair cells of the cochlea / Sensory processing of sound by inner hair cells of the cochlea / beta-2 adrenergic receptor binding / microvillus membrane / leukocyte cell-cell adhesion / regulation of cell size / leukocyte migration / renal absorption / pseudopodium / Recycling pathway of L1 / microvillus / negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction / negative regulation of mitotic cell cycle / transport across blood-brain barrier / phosphatase binding / endomembrane system / T cell proliferation / positive regulation of intrinsic apoptotic signaling pathway / protein-membrane adaptor activity / sperm midpiece / ruffle / cell adhesion molecule binding / Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation / filopodium / protein localization to plasma membrane / cell periphery / morphogenesis of an epithelium / PDZ domain binding / adherens junction / brush border membrane / sensory perception of sound / negative regulation of canonical Wnt signaling pathway / structural constituent of cytoskeleton / negative regulation of ERK1 and ERK2 cascade / Wnt signaling pathway / beta-catenin binding / positive regulation of protein catabolic process / adenylate cyclase-activating dopamine receptor signaling pathway / double-stranded RNA binding / Signaling by ALK fusions and activated point mutants / actin cytoskeleton / apical part of cell / actin binding / regulation of cell shape / actin cytoskeleton organization / protein-containing complex assembly / basolateral plasma membrane / vesicle / transmembrane transporter binding / blood microparticle / cytoskeleton / apical plasma membrane / negative regulation of cell population proliferation 類似検索 - 分子機能 EBP50, C-terminal / Na(+)/H(+) exchange regulatory cofactor NHERF-1/2 / EBP50, C-terminal / : / Ezrin/radixin/moesin, alpha-helical domain / Ezrin/radixin/moesin, alpha-helical domain / Moesin tail domain superfamily / Ezrin/radixin/moesin / Ezrin/radixin/moesin, C-terminal / ERM family, FERM domain C-lobe ... EBP50, C-terminal / Na(+)/H(+) exchange regulatory cofactor NHERF-1/2 / EBP50, C-terminal / : / Ezrin/radixin/moesin, alpha-helical domain / Ezrin/radixin/moesin, alpha-helical domain / Moesin tail domain superfamily / Ezrin/radixin/moesin / Ezrin/radixin/moesin, C-terminal / ERM family, FERM domain C-lobe / Ezrin/radixin/moesin family C terminal / Acyl-CoA Binding Protein - #10 / Ezrin/radixin/moesin-like / Acyl-CoA Binding Protein / FERM, C-terminal PH-like domain / FERM C-terminal PH-like domain / FERM C-terminal PH-like domain / FERM, N-terminal / FERM N-terminal domain / FERM domain signature 1. / FERM conserved site / FERM domain signature 2. / FERM central domain / FERM/acyl-CoA-binding protein superfamily / Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) / PH-domain like / FERM central domain / FERM superfamily, second domain / FERM domain / FERM domain profile. / Band 4.1 domain / Band 4.1 homologues / Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 / PDZ domain / PDZ domain profile. / Domain present in PSD-95, Dlg, and ZO-1/2. / PDZ domain / PDZ superfamily / Ubiquitin-like (UB roll) / PH-like domain superfamily / Ubiquitin-like domain superfamily / Roll / Roll / Up-down Bundle / Mainly Beta / Mainly Alpha / Alpha Beta 類似検索 - ドメイン・相同性 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 / Moesin 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 3.5 Å 詳細データ登録者 Finnerty, C.M. / Chambers, D. / Ingraffea, J. / Faber, H.R. / Karplus, P.A. / Bretscher, A. 引用ジャーナル : J.Cell.Sci. / 年 : 2004タイトル : The EBP50-moesin interaction involves a binding site regulated by direct masking on the FERM domain著者 : Finnerty, C.M. / Chambers, D. / Ingraffea, J. / Faber, H.R. / Karplus, P.A. / Bretscher, A. 履歴 登録 2004年2月23日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2004年6月29日 Provider : repository / タイプ : Initial release改定 1.1 2008年4月29日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Version format compliance改定 1.3 2023年8月23日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ref_seq_dif Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details
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