登録情報 | データベース: PDB / ID: 1s6o |
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タイトル | Solution structure and backbone dynamics of the apo-form of the second metal-binding domain of the Menkes protein ATP7A |
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要素 | Copper-transporting ATPase 1 |
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キーワード | HYDROLASE / copper homeostasis / metal transport / Menkes / Structural Proteomics in Europe / SPINE / Structural Genomics |
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機能・相同性 | 機能・相同性情報
epinephrine metabolic process / negative regulation of catecholamine metabolic process / L-tryptophan metabolic process / Ion influx/efflux at host-pathogen interface / copper-dependent protein binding / cerebellar Purkinje cell differentiation / elastic fiber assembly / tyrosine metabolic process / norepinephrine biosynthetic process / P-type divalent copper transporter activity ...epinephrine metabolic process / negative regulation of catecholamine metabolic process / L-tryptophan metabolic process / Ion influx/efflux at host-pathogen interface / copper-dependent protein binding / cerebellar Purkinje cell differentiation / elastic fiber assembly / tyrosine metabolic process / norepinephrine biosynthetic process / P-type divalent copper transporter activity / copper ion import / glycoprotein biosynthetic process / copper ion transmembrane transporter activity / P-type Cu+ transporter / P-type monovalent copper transporter activity / copper ion export / positive regulation of melanin biosynthetic process / superoxide dismutase copper chaperone activity / regulation of oxidative phosphorylation / catecholamine metabolic process / copper ion transport / serotonin metabolic process / trans-Golgi network transport vesicle / melanosome membrane / detoxification of copper ion / pyramidal neuron development / norepinephrine metabolic process / T-helper cell differentiation / cartilage development / collagen fibril organization / lung alveolus development / hair follicle morphogenesis / skin development / pigmentation / dendrite morphogenesis / Detoxification of Reactive Oxygen Species / blood vessel development / dopamine metabolic process / central nervous system neuron development / cuprous ion binding / Ion transport by P-type ATPases / blood vessel remodeling / intracellular copper ion homeostasis / ATP metabolic process / extracellular matrix organization / removal of superoxide radicals / release of cytochrome c from mitochondria / trans-Golgi network membrane / neuron projection morphogenesis / mitochondrion organization / locomotory behavior / trans-Golgi network / establishment of localization in cell / neuron cellular homeostasis / phagocytic vesicle membrane / late endosome / regulation of gene expression / early endosome membrane / neuron apoptotic process / basolateral plasma membrane / negative regulation of neuron apoptotic process / neuron projection / postsynaptic density / copper ion binding / axon / neuronal cell body / dendrite / perinuclear region of cytoplasm / endoplasmic reticulum / Golgi apparatus / ATP hydrolysis activity / ATP binding / membrane / plasma membrane / cytosol類似検索 - 分子機能 Heavy metal-associated domain, copper ion-binding / P-type ATPase, subfamily IB / Heavy-metal-associated, conserved site / Heavy-metal-associated domain. / Heavy-metal-associated domain / Heavy metal-associated domain superfamily / Heavy-metal-associated domain profile. / Heavy metal-associated domain, HMA / Alpha-Beta Plaits - #100 / E1-E2 ATPase ...Heavy metal-associated domain, copper ion-binding / P-type ATPase, subfamily IB / Heavy-metal-associated, conserved site / Heavy-metal-associated domain. / Heavy-metal-associated domain / Heavy metal-associated domain superfamily / Heavy-metal-associated domain profile. / Heavy metal-associated domain, HMA / Alpha-Beta Plaits - #100 / E1-E2 ATPase / P-type ATPase, haloacid dehalogenase domain / P-type ATPase, phosphorylation site / P-type ATPase, cytoplasmic domain N / E1-E2 ATPases phosphorylation site. / P-type ATPase, A domain superfamily / P-type ATPase / P-type ATPase, transmembrane domain superfamily / haloacid dehalogenase-like hydrolase / HAD superfamily / HAD-like superfamily / Alpha-Beta Plaits / 2-Layer Sandwich / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | 溶液NMR / restrained energy minimization |
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データ登録者 | Banci, L. / Bertini, I. / Del Conte, R. / D'Onofrio, M. / Rosato, A. / Structural Proteomics in Europe (SPINE) |
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引用 | ジャーナル: Biochemistry / 年: 2004 タイトル: Solution Structure and Backbone Dynamics of the Cu(I) and Apo Forms of the Second Metal-Binding Domain of the Menkes Protein ATP7A. 著者: Banci, L. / Bertini, I. / Del Conte, R. / D'Onofrio, M. / Rosato, A. |
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履歴 | 登録 | 2004年1月26日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2004年4月6日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年4月29日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2022年3月2日 | Group: Database references / Derived calculations カテゴリ: database_2 / pdbx_struct_assembly ...database_2 / pdbx_struct_assembly / pdbx_struct_oper_list / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details |
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改定 1.4 | 2024年5月22日 | Group: Data collection / カテゴリ: chem_comp_atom / chem_comp_bond |
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