- PDB-1re6: Localisation of Dynein Light Chains 1 and 2 and their Pro-apoptot... -
+
Open data
ID or keywords:
Loading...
-
Basic information
Entry
Database: PDB / ID: 1re6
Title
Localisation of Dynein Light Chains 1 and 2 and their Pro-apoptotic Ligands
Components
dynein light chain 2
Keywords
CONTRACTILE PROTEIN / dynein light chain / apoptosis / dimer
Function / homology
Function and homology information
Activation of BMF and translocation to mitochondria / Intraflagellar transport / Macroautophagy / myosin V complex / COPI-independent Golgi-to-ER retrograde traffic / 9+0 non-motile cilium / HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand / Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal / COPI-mediated anterograde transport / Aggrephagy ...Activation of BMF and translocation to mitochondria / Intraflagellar transport / Macroautophagy / myosin V complex / COPI-independent Golgi-to-ER retrograde traffic / 9+0 non-motile cilium / HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand / Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal / COPI-mediated anterograde transport / Aggrephagy / Mitotic Prometaphase / EML4 and NUDC in mitotic spindle formation / Resolution of Sister Chromatid Cohesion / RHO GTPases Activate Formins / Separation of Sister Chromatids / MHC class II antigen presentation / cytoplasmic dynein complex / dynein intermediate chain binding / microtubule-based process / scaffold protein binding / microtubule / postsynaptic density / centrosome / glutamatergic synapse / protein-containing complex binding / identical protein binding / cytoplasm Similarity search - Function
Protein Inhibitor Of Neuronal Nitric Oxide Synthase / Protein Inhibitor Of Neuronal Nitric Oxide Synthase; / Dynein light chain, type 1/2, conserved site / Dynein light chain type 1 signature. / Dynein light chain type 1 / Dynein light chain, type 1/2 / Dynein light chain superfamily / Dynein light chain type 1 / 2-Layer Sandwich / Alpha Beta Similarity search - Domain/homology
structures with acceptable covalent geometry,structures with favorable non-bond energy,structures with the least restraint violations,structures with the lowest energy,target function
Representative
Model #1
closest to the average
-
Components
#1: Protein
dyneinlightchain2
Mass: 10776.303 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Mus musculus (house mouse) / Gene: DLC2 / Plasmid: PGEX6P-3 / Species (production host): Escherichia coli / Production host: Escherichia coli BL21(DE3) (bacteria) / Strain (production host): BL21 (DE3) / References: GenBank: 18087731, UniProt: Q9D0M5*PLUS
-
Experimental details
-
Experiment
Experiment
Method: SOLUTION NMR
NMR experiment
Conditions-ID
Experiment-ID
Solution-ID
Type
1
1
1
2D NOESY
1
2
2
3D 15N-separated NOESY
1
3
3
3D 13C-separated NOESY
1
4
2
HNHA
NMR details
Text: THE STRUCTURE WAS DETERMINED USING STANDARD 2D AND 3D HETERONUCLEAR TECHNIQUES
Method: distance geometry, simulated annealing, molecular dynamics, torsion angle dynamics Software ordinal: 1 Details: the structures are based on a total of 1602 restraints, 1417 are NOE derived distance constraints,99 are interprotomer distance constraints, 127 are dihedral angle restraints and 29 hydrogen bonds.
NMR representative
Selection criteria: closest to the average
NMR ensemble
Conformer selection criteria: structures with acceptable covalent geometry,structures with favorable non-bond energy,structures with the least restraint violations,structures with the lowest energy,target function Conformers calculated total number: 256 / Conformers submitted total number: 20
+
About Yorodumi
-
News
-
Feb 9, 2022. New format data for meta-information of EMDB entries
New format data for meta-information of EMDB entries
Version 3 of the EMDB header file is now the official format.
The previous official version 1.9 will be removed from the archive.
In the structure databanks used in Yorodumi, some data are registered as the other names, "COVID-19 virus" and "2019-nCoV". Here are the details of the virus and the list of structure data.
Jan 31, 2019. EMDB accession codes are about to change! (news from PDBe EMDB page)
EMDB accession codes are about to change! (news from PDBe EMDB page)
The allocation of 4 digits for EMDB accession codes will soon come to an end. Whilst these codes will remain in use, new EMDB accession codes will include an additional digit and will expand incrementally as the available range of codes is exhausted. The current 4-digit format prefixed with “EMD-” (i.e. EMD-XXXX) will advance to a 5-digit format (i.e. EMD-XXXXX), and so on. It is currently estimated that the 4-digit codes will be depleted around Spring 2019, at which point the 5-digit format will come into force.
The EM Navigator/Yorodumi systems omit the EMD- prefix.
Related info.:Q: What is EMD? / ID/Accession-code notation in Yorodumi/EM Navigator
Yorodumi is a browser for structure data from EMDB, PDB, SASBDB, etc.
This page is also the successor to EM Navigator detail page, and also detail information page/front-end page for Omokage search.
The word "yorodu" (or yorozu) is an old Japanese word meaning "ten thousand". "mi" (miru) is to see.
Related info.:EMDB / PDB / SASBDB / Comparison of 3 databanks / Yorodumi Search / Aug 31, 2016. New EM Navigator & Yorodumi / Yorodumi Papers / Jmol/JSmol / Function and homology information / Changes in new EM Navigator and Yorodumi