登録情報 データベース : PDB / ID : 1pdg 構造の表示 ダウンロードとリンクタイトル CRYSTAL STRUCTURE OF HUMAN PLATELET-DERIVED GROWTH FACTOR BB 要素PLATELET-DERIVED GROWTH FACTOR BB 詳細 キーワード GROWTH FACTOR機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
metanephric glomerular mesangial cell development / positive regulation of vascular associated smooth muscle cell dedifferentiation / positive regulation of metanephric mesenchymal cell migration / negative regulation of phosphatidylinositol biosynthetic process / platelet-derived growth factor complex / positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway / positive regulation of glomerular filtration / cellular response to mycophenolic acid / superoxide-generating NADPH oxidase activator activity / negative regulation of vascular associated smooth muscle cell differentiation ... metanephric glomerular mesangial cell development / positive regulation of vascular associated smooth muscle cell dedifferentiation / positive regulation of metanephric mesenchymal cell migration / negative regulation of phosphatidylinositol biosynthetic process / platelet-derived growth factor complex / positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway / positive regulation of glomerular filtration / cellular response to mycophenolic acid / superoxide-generating NADPH oxidase activator activity / negative regulation of vascular associated smooth muscle cell differentiation / positive regulation of hyaluronan biosynthetic process / smooth muscle adaptation / platelet-derived growth factor binding / positive regulation of protein autophosphorylation / interleukin-18-mediated signaling pathway / positive regulation of glomerular mesangial cell proliferation / Signaling by PDGF / positive regulation of chemotaxis / paracrine signaling / platelet-derived growth factor receptor binding / positive regulation of vascular associated smooth muscle cell migration / positive regulation of cell-substrate adhesion / positive regulation of smooth muscle cell migration / positive regulation of DNA biosynthetic process / positive regulation of calcium ion import / chemoattractant activity / platelet-derived growth factor receptor signaling pathway / positive regulation of MAP kinase activity / monocyte chemotaxis / positive regulation of cell division / Non-integrin membrane-ECM interactions / negative regulation of platelet activation / positive regulation of blood vessel endothelial cell migration / embryonic placenta development / positive regulation of vascular associated smooth muscle cell proliferation / collagen binding / cellular response to platelet-derived growth factor stimulus / positive regulation of endothelial cell proliferation / positive regulation of smooth muscle cell proliferation / positive regulation of mitotic nuclear division / Downstream signal transduction / negative regulation of miRNA transcription / reactive oxygen species metabolic process / platelet alpha granule lumen / peptidyl-tyrosine phosphorylation / cell chemotaxis / growth factor activity / cellular response to growth factor stimulus / positive regulation of miRNA transcription / response to wounding / Golgi lumen / positive regulation of fibroblast proliferation / positive regulation of reactive oxygen species metabolic process / Constitutive Signaling by Aberrant PI3K in Cancer / Platelet degranulation / PIP3 activates AKT signaling / : / heart development / RAF/MAP kinase cascade / PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling / angiogenesis / basolateral plasma membrane / gene expression / positive regulation of ERK1 and ERK2 cascade / protein phosphorylation / positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction / positive regulation of MAPK cascade / intracellular signal transduction / positive regulation of cell migration / endoplasmic reticulum lumen / protein heterodimerization activity / Golgi membrane / negative regulation of gene expression / negative regulation of DNA-templated transcription / positive regulation of cell population proliferation / positive regulation of gene expression / positive regulation of DNA-templated transcription / cell surface / protein homodimerization activity / extracellular space / extracellular region / identical protein binding / cytoplasm 類似検索 - 分子機能 Platelet-derived growth factor, N-terminal / Platelet-derived growth factor, N terminal region / PDGF/VEGF domain / Platelet-derived growth factor, conserved site / PDGF/VEGF domain / Platelet-derived growth factor (PDGF) family signature. / Platelet-derived growth factor (PDGF) family profile. / Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family / Cystine Knot Cytokines, subunit B / Cystine-knot cytokines ... Platelet-derived growth factor, N-terminal / Platelet-derived growth factor, N terminal region / PDGF/VEGF domain / Platelet-derived growth factor, conserved site / PDGF/VEGF domain / Platelet-derived growth factor (PDGF) family signature. / Platelet-derived growth factor (PDGF) family profile. / Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family / Cystine Knot Cytokines, subunit B / Cystine-knot cytokines / Cystine-knot cytokine / Ribbon / Mainly Beta 類似検索 - ドメイン・相同性生物種 Homo sapiens (ヒト)手法 X線回折 / 解像度 : 3 Å 詳細データ登録者 Oefner, C. / Darcy, A.D. / Winkler, F.K. / Eggimann, B. / Hosnag, M. 引用ジャーナル : EMBO J. / 年 : 1992タイトル : Crystal structure of human platelet-derived growth factor BB.著者 : Oefner, C. / D'Arcy, A. / Winkler, F.K. / Eggimann, B. / Hosang, M. 履歴 登録 1992年7月14日 処理サイト : BNL改定 1.0 1994年1月31日 Provider : repository / タイプ : Initial release改定 1.1 2008年3月24日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Version format compliance改定 1.3 2017年11月29日 Group : Derived calculations / Other / カテゴリ : pdbx_database_status / struct_conf / Item : _pdbx_database_status.process_site改定 1.4 2024年11月13日 Group : Data collection / Database references / Structure summaryカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_entry_details / pdbx_modification_feature Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
すべて表示 表示を減らす