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Open data
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Basic information
Entry | Database: PDB / ID: 1ocw | ||||||
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Title | Free conformation Ab2 of the IgE SPE-7 | ||||||
![]() | (IMMUNOGLOBULIN E) x 2 | ||||||
![]() | IMMUNE SYSTEM / ANTIBODY / ALLERGY / CONFORMATIONAL DIVERSITY / MULTISPECIFICITY | ||||||
Function / homology | ![]() immunoglobulin complex / adaptive immune response / immune response / extracellular space Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() ![]() | ||||||
![]() | James, L.C. / Roversi, P. / Tawfik, D. | ||||||
![]() | ![]() Title: Antibody Multispecificity Mediated by Conformational Diversity Authors: James, L.C. / Roversi, P. / Tawfik, D. | ||||||
History |
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Remark 700 | SHEET THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN ORDER TO REPRESENT THIS FEATURE IN ... SHEET THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN ORDER TO REPRESENT THIS FEATURE IN THE SHEET RECORDS BELOW, TWO SHEETS ARE DEFINED. |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 59.5 KB | Display | ![]() |
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PDB format | ![]() | 43.3 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 410.8 KB | Display | ![]() |
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Full document | ![]() | 439.5 KB | Display | |
Data in XML | ![]() | 11.8 KB | Display | |
Data in CIF | ![]() | 15.6 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 1oaqSC ![]() 1oarC ![]() 1oauC ![]() 1oaxC ![]() 1oayC ![]() 1oazC S: Starting model for refinement C: citing same article ( |
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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1 | ![]()
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Unit cell |
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Components
#1: Antibody | Mass: 13616.237 Da / Num. of mol.: 1 / Fragment: FV REGION, RESIDUES 1-121 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() |
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#2: Antibody | Mass: 12584.981 Da / Num. of mol.: 1 / Fragment: FV REGION, RESIDUES 1-120 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() |
#3: Water | ChemComp-HOH / |
-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 1.5 Å3/Da / Density % sol: 40 % |
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Crystal grow | pH: 5 / Details: 0.1M HEPES, PH7.5, 70% MPD, pH 5.00 |
-Data collection
Diffraction | Mean temperature: 100 K |
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Diffraction source | Source: ![]() |
Detector | Type: MARRESEARCH / Detector: IMAGE PLATE / Date: Aug 15, 2002 / Details: MIRRORS |
Radiation | Monochromator: NI FILTER / Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength: 1.5418 Å / Relative weight: 1 |
Reflection | Resolution: 2.01→28.17 Å / Num. obs: 13952 / % possible obs: 94.4 % / Observed criterion σ(I): 2 / Redundancy: 9.9 % / Rmerge(I) obs: 0.051 |
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Processing
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Refinement | Method to determine structure: ![]() Starting model: PDB ENTRY 1OAQ Resolution: 2→28.17 Å Details: REFINEMENT OF TWINNING FRACTION: ALPHA=0.50(05). REFINEMENT WITH IDEALISED HYDROGEN ATOMS TWINNED DATA; APPARENT SYMMETRY I422; TWINNING OPERATOR
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Refinement step | Cycle: LAST / Resolution: 2→28.17 Å
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Refinement | *PLUS Rfactor all: 0.21 / Rfactor obs: 0.252 / Rfactor Rfree: 0.21 | ||||||||||||||||||||
Solvent computation | *PLUS | ||||||||||||||||||||
Displacement parameters | *PLUS |