Sertoli cell proliferation / Bcl-2 family protein complex / extrinsic apoptotic signaling pathway in absence of ligand / release of cytochrome c from mitochondria / intrinsic apoptotic signaling pathway in response to DNA damage / disordered domain specific binding / channel activity / spermatogenesis / regulation of apoptotic process / mitochondrial outer membrane ...Sertoli cell proliferation / Bcl-2 family protein complex / extrinsic apoptotic signaling pathway in absence of ligand / release of cytochrome c from mitochondria / intrinsic apoptotic signaling pathway in response to DNA damage / disordered domain specific binding / channel activity / spermatogenesis / regulation of apoptotic process / mitochondrial outer membrane / positive regulation of apoptotic process / negative regulation of apoptotic process / mitochondrion / identical protein binding / cytosol 類似検索 - 分子機能
Apoptosis regulator, Bcl-W / Apoptosis regulator, Bcl-2, BH4 motif, conserved site / Apoptosis regulator, Bcl-2 family BH4 motif signature. / Apoptosis regulator, Bcl-2 protein, BH4 / Bcl-2 homology region 4 / Apoptosis regulator, Bcl-2 family BH4 motif profile. / BH4 Bcl-2 homology region 4 / Blc2-like / Apoptosis Regulator Bcl-x / Apoptosis regulator, Bcl-2, BH1 motif, conserved site ...Apoptosis regulator, Bcl-W / Apoptosis regulator, Bcl-2, BH4 motif, conserved site / Apoptosis regulator, Bcl-2 family BH4 motif signature. / Apoptosis regulator, Bcl-2 protein, BH4 / Bcl-2 homology region 4 / Apoptosis regulator, Bcl-2 family BH4 motif profile. / BH4 Bcl-2 homology region 4 / Blc2-like / Apoptosis Regulator Bcl-x / Apoptosis regulator, Bcl-2, BH1 motif, conserved site / Apoptosis regulator, Bcl-2 family BH1 motif signature. / Apoptosis regulator, Bcl-2, BH2 motif, conserved site / Apoptosis regulator, Bcl-2 family BH2 motif signature. / Bcl-2 family / BCL (B-Cell lymphoma); contains BH1, BH2 regions / Bcl2-like / Bcl-2, Bcl-2 homology region 1-3 / Apoptosis regulator proteins, Bcl-2 family / BCL2-like apoptosis inhibitors family profile. / Bcl-2-like superfamily / Orthogonal Bundle / Mainly Alpha 類似検索 - ドメイン・相同性
タイプ: Bruker DRX / 製造業者: Bruker / モデル: DRX / 磁場強度: 600 MHz
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解析
NMR software
名称
バージョン
開発者
分類
XwinNMR
2.6
BrukerA.G.
collection
XEASY
1.3
Bartels et al. J. Biomol. NMR 1995, 6, 1-10.
データ解析
DYANA
1.5
Guntert et al. J. Mol. Biol. 1997, 273, 283-298.
構造決定
CNS
1.1
Brunger et al. Acta Crystallogr. D, 1998, 54, 905-921.
精密化
精密化
手法: distance geometry torsion angle dynamics simulated annealing ソフトェア番号: 1 詳細: the structures are based on a total of 3871 constraints. Distance constraints: 694 intraresidue; 843 sequential; 912 short range; 993 long range; 64 hydrogen bonds Dihedral angle constraints: ...詳細: the structures are based on a total of 3871 constraints. Distance constraints: 694 intraresidue; 843 sequential; 912 short range; 993 long range; 64 hydrogen bonds Dihedral angle constraints: 136 phi constraints; 101 psi constraints; 34 chi1 constraints; 30 chi2 constraints
代表構造
選択基準: closest to the average
NMRアンサンブル
コンフォーマー選択の基準: structures with acceptable covalent geometry, structures with the least restraint violations, structures with the lowest energy, target function 計算したコンフォーマーの数: 256 / 登録したコンフォーマーの数: 20