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Open data
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Basic information
Entry | Database: PDB / ID: 1lqc | ||||||
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Title | LAC REPRESSOR HEADPIECE (RESIDUES 1-56), NMR, 32 STRUCTURES | ||||||
![]() | LAC REPRESSOR | ||||||
![]() | TRANSCRIPTION REGULATION / LAC OPERON / LAC REPRESSOR / HEADPIECE / DNA | ||||||
Function / homology | ![]() DNA-binding transcription repressor activity / cis-regulatory region sequence-specific DNA binding / transcription cis-regulatory region binding / DNA-binding transcription factor activity / negative regulation of DNA-templated transcription / regulation of DNA-templated transcription / identical protein binding / cytosol Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | SOLUTION NMR | ||||||
![]() | Slijper, M. / Bonvin, A.M.J.J. / Boelens, R. / Kaptein, R. | ||||||
![]() | ![]() Title: Refined structure of lac repressor headpiece (1-56) determined by relaxation matrix calculations from 2D and 3D NOE data: change of tertiary structure upon binding to the lac operator. Authors: Slijper, M. / Bonvin, A.M. / Boelens, R. / Kaptein, R. #1: ![]() Title: Backbone and Sidechain Dynamics of Lac Repressor Headpiece (1-56) and its Complex with DNA Authors: Slijper, M. / Boelens, R. / Davis, A.L. / Konings, R.N.H. / Van Der Marel, G.A. / Van Bloom, J.H. #2: ![]() Title: Application of Structure Refinement Using 3D Noe-Noe Spectroscopy to Lac Repressor Headpiece (1-56) Authors: Slijper, M. / Bonvin, M.J.J. / Boelens, R. / Kaptein, R. #3: ![]() Title: Structure of the Complex of Lac Repressor Headpiece and an 11 Base-Pair Half-Operator Determined by Nuclear Magnetic Resonance Spectroscopy and Restrained Molecular Dynamics Authors: Chuprina, V.P. / Rullmann, J.A. / Lamerichs, R.M. / Van Boom, J.H. / Boelens, R. / Kaptein, R. #4: ![]() Title: Two-Dimensional 1H-NMR Studies on the Lac Repressor DNA Binding Domain: Further Resonance Assignments and Identification of Nuclear Overhauser Enhancements Authors: Zuiderweg, E.R. / Scheek, R.M. / Kaptein, R. #5: ![]() Title: Stereospecific Assignments of 1H-NMR Methyl Lines and Conformation of Valyl Residues in the Lac Repressor Headpiece Authors: Zuiderweg, E.R.P. / Boelens, R. / Kaptein, R. #6: ![]() Title: Sequence-Specific Resonance Assignments in the 1H Nuclear-Magnetic-Resonance Spectrum of the Lac Repressor DNA-Binding Domain 1-51 from Escherichia Coli by Two-Dimensional Spectroscopy Authors: Zuiderweg, E.R. / Kaptein, R. / Wuthrich, K. | ||||||
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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PDBx/mmCIF format | ![]() | 257.6 KB | Display | ![]() |
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PDB format | ![]() | 201.7 KB | Display | ![]() |
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-Validation report
Summary document | ![]() | 355.4 KB | Display | ![]() |
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Full document | ![]() | 585.2 KB | Display | |
Data in XML | ![]() | 34.3 KB | Display | |
Data in CIF | ![]() | 58.1 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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NMR ensembles |
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Components
#1: Protein | Mass: 6233.070 Da / Num. of mol.: 1 / Fragment: HEADPIECE, RESIDUES 1 - 56 Source method: isolated from a genetically manipulated source Details: THE PROTEIN CONTAINS THE FIRST 56 N-TERMINAL RESIDUES (I.E., THE DNA BINDING REGION) OF THE COMPLETE LAC REPRESSOR PROTEIN Source: (gene. exp.) ![]() ![]() Gene (production host): LAC I, THE PART ENCODING ONLY THE FIRST 56 AMINO ACIDS Production host: ![]() ![]() |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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Sample preparation
Crystal grow | *PLUS Method: other / Details: NMR |
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Processing
NMR software | Name: DINOSAUR / Developer: BONVIN,VIS,BREG,BURGERING,BOELENS,KAPTEIN / Classification: refinement |
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NMR ensemble | Conformers submitted total number: 32 |