+
Open data
-
Basic information
Entry | Database: PDB / ID: 1kig | ||||||
---|---|---|---|---|---|---|---|
Title | BOVINE FACTOR XA | ||||||
![]() |
| ||||||
![]() | COMPLEX (PROTEASE/INHIBITOR) / GLYCOPROTEIN / SERINE PROTEASE / PLASMA / BLOOD COAGULATION / COMPLEX (PROTEASE-INHIBITOR) / COMPLEX (PROTEASE-INHIBITOR) complex | ||||||
Function / homology | ![]() coagulation factor Xa / positive regulation of leukocyte chemotaxis / serine-type endopeptidase inhibitor activity / blood coagulation / serine-type endopeptidase activity / calcium ion binding / proteolysis / extracellular space Similarity search - Function | ||||||
Biological species | ![]() ![]() ![]() | ||||||
Method | ![]() | ||||||
![]() | Wei, A. / Alexander, R. / Chang, C.-H. | ||||||
![]() | ![]() Title: Unexpected binding mode of tick anticoagulant peptide complexed to bovine factor Xa. Authors: Wei, A. / Alexander, R.S. / Duke, J. / Ross, H. / Rosenfeld, S.A. / Chang, C.H. | ||||||
History |
|
-
Structure visualization
Structure viewer | Molecule: ![]() ![]() |
---|
-
Downloads & links
-
Download
PDBx/mmCIF format | ![]() | 73.5 KB | Display | ![]() |
---|---|---|---|---|
PDB format | ![]() | 53.7 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 382.5 KB | Display | ![]() |
---|---|---|---|---|
Full document | ![]() | 405.2 KB | Display | |
Data in XML | ![]() | 11.2 KB | Display | |
Data in CIF | ![]() | 15.7 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Similar structure data |
---|
-
Links
-
Assembly
Deposited unit | ![]()
| ||||||||
---|---|---|---|---|---|---|---|---|---|
1 |
| ||||||||
Unit cell |
|
-
Components
#1: Protein | Mass: 26847.541 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() | ||
---|---|---|---|
#2: Protein | Mass: 5633.237 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() | ||
#3: Protein | Mass: 6992.614 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() | ||
Compound details | THE TWO CHAINS OF BOVINE FACTOR XA ARE FORMED FROM A SINGLE-CHAIN PRECURSOR BY THE EXCISION OF TWO ...THE TWO CHAINS OF BOVINE FACTOR XA ARE FORMED FROM A SINGLE-CHAIN PRECURSOR BY THE EXCISION OF TWO ARG RESIDUES AND ARE HELD TOGETHER BY ONE OR MORE DISULFIDE BONDS. | ||
Sequence details | THE RESIDUE NUMBERING SCHEME WAS CHOSEN TO PROVIDE MAXIMUM HOMOLOGY WITH THE SEQUENCE OF CHYMOTRYPSSource details | THE RTAP INHIBITOR WAS PRODUCED BY RECOMBINAN | |
-Experimental details
-Experiment
Experiment | Method: ![]() |
---|
-
Sample preparation
Crystal | Density Matthews: 3.86 Å3/Da / Density % sol: 68.12 % | ||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Crystal grow | *PLUS Temperature: 4 ℃ / pH: 7 / Method: vapor diffusion, hanging drop | ||||||||||||||||||||||||
Components of the solutions | *PLUS
|
-Data collection
Radiation | Scattering type: x-ray |
---|---|
Radiation wavelength | Relative weight: 1 |
Reflection | *PLUS Highest resolution: 3 Å / Num. obs: 10255 / % possible obs: 83 % / Num. measured all: 67914 / Rmerge(I) obs: 0.114 |
-
Processing
Software |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Refinement | Rfactor Rwork: 0.187 / Rfactor obs: 0.187 / Highest resolution: 3 Å | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement step | Cycle: LAST / Highest resolution: 3 Å
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refine LS restraints |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement | *PLUS Num. reflection obs: 9573 / σ(F): 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Solvent computation | *PLUS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Displacement parameters | *PLUS |