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Open data
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Basic information
Entry | Database: PDB / ID: 1gnd | ||||||
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Title | GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR, ALPHA-ISOFORM | ||||||
![]() | GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR | ||||||
![]() | GTPASE ACTIVATION | ||||||
Function / homology | ![]() RAB GEFs exchange GTP for GDP on RABs / Rab GDP-dissociation inhibitor activity / negative regulation of protein targeting to membrane / Rab protein signal transduction / negative regulation of axonogenesis / vesicle-mediated transport / GTPase activator activity / protein transport / Golgi apparatus / cytoplasm / cytosol Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() | ||||||
![]() | Schalk, I. / Zeng, K. / Wu, S.-K. / Stura, E.A. / Metteson, J. / Huang, M. / Tandon, A. / Wilson, I.A. / Balch, W.E. | ||||||
![]() | ![]() Title: Structure and mutational analysis of Rab GDP-dissociation inhibitor. Authors: Schalk, I. / Zeng, K. / Wu, S.K. / Stura, E.A. / Matteson, J. / Huang, M. / Tandon, A. / Wilson, I.A. / Balch, W.E. #1: ![]() Title: Crystallization and Preliminary Crystallographic Data for Rab Guanine Nucleotide Dissociation Inhibitor (Rabgdi) from Bovine Brain Authors: Schalk, I.J. / Stura, E.A. / Matteson, J. / Wilson, I.A. / Balch, W.E. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 105.9 KB | Display | ![]() |
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PDB format | ![]() | 80.4 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 366.3 KB | Display | ![]() |
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Full document | ![]() | 374.4 KB | Display | |
Data in XML | ![]() | 10.5 KB | Display | |
Data in CIF | ![]() | 17.7 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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1 |
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Unit cell |
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Components
#1: Protein | Mass: 50620.461 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Details: ALPHA-ISOFORM / Source: (gene. exp.) ![]() ![]() ![]() ![]() |
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#2: Water | ChemComp-HOH / |
-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 2.41 Å3/Da / Density % sol: 45 % |
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Crystal grow | *PLUS pH: 6.25 / Method: unknown |
Components of the solutions | *PLUS Conc.: 1.73 M / Common name: ammonium salfate |
-Data collection
Diffraction source | Wavelength: 1.5418 |
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Detector | Type: SIEMENS / Detector: AREA DETECTOR / Date: Dec 29, 1994 |
Radiation | Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength: 1.5418 Å / Relative weight: 1 |
Reflection | Num. obs: 42588 / % possible obs: 97.1 % / Redundancy: 3 % / Rmerge(I) obs: 0.1 |
Reflection | *PLUS Highest resolution: 1.81 Å |
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Processing
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Refinement | Resolution: 1.81→6 Å / σ(F): 2
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Displacement parameters | Biso mean: 28.2 Å2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refine analyze | Luzzati coordinate error obs: 0.2 Å | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement step | Cycle: LAST / Resolution: 1.81→6 Å
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Refine LS restraints |
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Software | *PLUS Name: ![]() | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement | *PLUS Num. reflection all: 40982 / Rfactor all: 0.211 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Solvent computation | *PLUS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Displacement parameters | *PLUS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refine LS restraints | *PLUS
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