- PDB-1faf: NMR STRUCTURE OF THE N-TERMINAL J DOMAIN OF MURINE POLYOMAVIRUS T... -
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Basic information
Entry
Database: PDB / ID: 1faf
Title
NMR STRUCTURE OF THE N-TERMINAL J DOMAIN OF MURINE POLYOMAVIRUS T ANTIGENS.
Components
LARGE T ANTIGEN
Keywords
VIRAL PROTEIN / J DOMAIN / HPD MOTIF / ANTI-PARALLEL HAIRPIN OF HELICES
Function / homology
Function and homology information
symbiont-mediated suppression of host JAK-STAT cascade via inhibition of JAK1 activity / symbiont-mediated perturbation of host cell cycle G1/S transition checkpoint / DNA replication origin binding / Hydrolases; Acting on acid anhydrides; Acting on acid anhydrides to facilitate cellular and subcellular movement / DNA replication / hydrolase activity / symbiont-mediated suppression of host type I interferon-mediated signaling pathway / host cell nucleus / ATP binding / metal ion binding Similarity search - Function
Large T antigen, polyomavirus, C-terminal / Zinc finger, large T-antigen D1-type / Origin of replication binding protein / Polyomavirus large T antigen C-terminus / Large T-antigen (T-ag) origin-binding domain (OBD) profile. / Zinc finger large T-antigen (T-ag) D1-type profile. / T antigen, Ori-binding / DnaJ domain / Zinc finger, large T-antigen D1 domain superfamily / Helicase, superfamily 3, DNA virus ...Large T antigen, polyomavirus, C-terminal / Zinc finger, large T-antigen D1-type / Origin of replication binding protein / Polyomavirus large T antigen C-terminus / Large T-antigen (T-ag) origin-binding domain (OBD) profile. / Zinc finger large T-antigen (T-ag) D1-type profile. / T antigen, Ori-binding / DnaJ domain / Zinc finger, large T-antigen D1 domain superfamily / Helicase, superfamily 3, DNA virus / Superfamily 3 helicase of DNA viruses domain profile. / DnaJ molecular chaperone homology domain / Chaperone J-domain superfamily / DnaJ domain / Helix Hairpins / P-loop containing nucleoside triphosphate hydrolase / Orthogonal Bundle / Mainly Alpha Similarity search - Domain/homology
Type: Bruker DRX / Manufacturer: Bruker / Model: DRX / Field strength: 500 MHz
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Processing
NMR software
Name
Version
Classification
XwinNMR
1.3
structuresolution
SYBYL TRIAD
6.3
structuresolution
CNS
1
structuresolution
CNS
1
refinement
Refinement
Method: TORSION ANGLE DYNAMICS, SIMULATED ANNEALING IN CARTESIAN SPACE Software ordinal: 1
NMR ensemble
Conformer selection criteria: STRUCTURES WITH FAVORABLE NON-BOND ENERGY,STRUCTURES WITH THE LOWEST ENERGY Conformers calculated total number: 100 / Conformers submitted total number: 47
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