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Yorodumi- PDB-1erh: THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE EXTRACELLULAR REGION ... -
+Open data
-Basic information
Entry | Database: PDB / ID: 1erh | ||||||
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Title | THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE EXTRACELLULAR REGION OF THE COMPLEMENT REGULATORY PROTEIN, CD59, A NEW CELL SURFACE PROTEIN DOMAIN RELATED TO NEUROTOXINS | ||||||
Components | CD59 | ||||||
Keywords | COMPLEMENT FACTOR | ||||||
Function / homology | Function and homology information negative regulation of activation of membrane attack complex / complement binding / regulation of complement-dependent cytotoxicity / regulation of complement activation / Cargo concentration in the ER / COPII-mediated vesicle transport / tertiary granule membrane / COPI-mediated anterograde transport / specific granule membrane / transport vesicle ...negative regulation of activation of membrane attack complex / complement binding / regulation of complement-dependent cytotoxicity / regulation of complement activation / Cargo concentration in the ER / COPII-mediated vesicle transport / tertiary granule membrane / COPI-mediated anterograde transport / specific granule membrane / transport vesicle / endoplasmic reticulum-Golgi intermediate compartment membrane / Regulation of Complement cascade / ER to Golgi transport vesicle membrane / blood coagulation / vesicle / cell surface receptor signaling pathway / Golgi membrane / external side of plasma membrane / focal adhesion / endoplasmic reticulum membrane / Neutrophil degranulation / cell surface / extracellular space / extracellular exosome / membrane / plasma membrane Similarity search - Function | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | SOLUTION NMR | ||||||
Authors | Kieffer, B. / Driscoll, P.C. / Campbell, I.D. / Willis, A.C. / Van Der Merwe, P.A. / Davis, S.J. | ||||||
Citation | Journal: Biochemistry / Year: 1994 Title: Three-dimensional solution structure of the extracellular region of the complement regulatory protein CD59, a new cell-surface protein domain related to snake venom neurotoxins. Authors: Kieffer, B. / Driscoll, P.C. / Campbell, I.D. / Willis, A.C. / van der Merwe, P.A. / Davis, S.J. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1erh.cif.gz | 21.5 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1erh.ent.gz | 11.1 KB | Display | PDB format |
PDBx/mmJSON format | 1erh.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 1erh_validation.pdf.gz | 262.1 KB | Display | wwPDB validaton report |
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Full document | 1erh_full_validation.pdf.gz | 279.6 KB | Display | |
Data in XML | 1erh_validation.xml.gz | 3.9 KB | Display | |
Data in CIF | 1erh_validation.cif.gz | 4.6 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/er/1erh ftp://data.pdbj.org/pub/pdb/validation_reports/er/1erh | HTTPS FTP |
-Related structure data
-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein | Mass: 8095.213 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Homo sapiens (human) / References: UniProt: P13987 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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-Sample preparation
Crystal grow | *PLUS Method: other / Details: NMR |
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-Processing
Software |
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NMR software | Name: X-PLOR / Developer: BRUNGER / Classification: refinement | ||||||||
NMR ensemble | Conformers submitted total number: 10 |