登録情報 | データベース: PDB / ID: 1bak |
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タイトル | SIGNAL TRANSDUCTION PLECKSTRIN HOMOLOGY DOMAIN OF G-PROTEIN COUPLED RECEPTOR KINASE 2 (BETA-ADRENERGIC RECEPTOR KINASE 1), C-TERMINAL EXTENDED, NMR, 20 STRUCTURES |
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要素 | G-PROTEIN COUPLED RECEPTOR KINASE 2 |
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キーワード | TRANSFERASE / PLECKSTRIN HOMOLOGY DOMAIN / PH DOMAIN / SIGNAL TRANSDUCTION / G-BETA-GAMMA BINDING DOMAIN / BETA-ADRENERGIC RECEPTOR KINASE / BETA-ARK / G-PROTEIN COUPLED RECEPTOR KINASE (GRK-2) |
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機能・相同性 | 機能・相同性情報
beta-adrenergic-receptor kinase / negative regulation of the force of heart contraction by chemical signal / negative regulation of relaxation of smooth muscle / beta-adrenergic receptor kinase activity / G protein-coupled receptor kinase activity / Edg-2 lysophosphatidic acid receptor binding / alpha-2A adrenergic receptor binding / tachykinin receptor signaling pathway / positive regulation of catecholamine secretion / Activation of SMO ...beta-adrenergic-receptor kinase / negative regulation of the force of heart contraction by chemical signal / negative regulation of relaxation of smooth muscle / beta-adrenergic receptor kinase activity / G protein-coupled receptor kinase activity / Edg-2 lysophosphatidic acid receptor binding / alpha-2A adrenergic receptor binding / tachykinin receptor signaling pathway / positive regulation of catecholamine secretion / Activation of SMO / negative regulation of striated muscle contraction / desensitization of G protein-coupled receptor signaling pathway / regulation of the force of heart contraction / Calmodulin induced events / cardiac muscle contraction / viral genome replication / G protein-coupled receptor binding / G protein-coupled acetylcholine receptor signaling pathway / receptor internalization / cilium / Cargo recognition for clathrin-mediated endocytosis / presynapse / heart development / G alpha (s) signalling events / postsynapse / G alpha (q) signalling events / peptidyl-serine phosphorylation / protein kinase activity / symbiont entry into host cell / G protein-coupled receptor signaling pathway / ATP binding / membrane / plasma membrane / cytoplasm / cytosol類似検索 - 分子機能 GPCR kinase / Regulator of G protein signaling domain / RGS, subdomain 2 / RGS domain / RGS domain profile. / Regulator of G protein signalling domain / RGS domain superfamily / Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) / PH-domain like / Extension to Ser/Thr-type protein kinases ...GPCR kinase / Regulator of G protein signaling domain / RGS, subdomain 2 / RGS domain / RGS domain profile. / Regulator of G protein signalling domain / RGS domain superfamily / Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) / PH-domain like / Extension to Ser/Thr-type protein kinases / AGC-kinase, C-terminal / AGC-kinase C-terminal domain profile. / PH domain / PH domain profile. / Pleckstrin homology domain. / Pleckstrin homology domain / PH-like domain superfamily / Roll / Serine/threonine-protein kinase, active site / Serine/Threonine protein kinases active-site signature. / Protein kinase domain / Serine/Threonine protein kinases, catalytic domain / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / Mainly Beta類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | 溶液NMR / distance geometry |
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データ登録者 | Fushman, D. / Cowburn, D. |
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引用 | #1: ジャーナル: Biochemistry / 年: 1995タイトル: Structural Studies on the Ph Domains of Dbl, SOS1, Irs-1, and Beta Ark1 and Their Differential Binding to G Beta Gamma Subunits 著者: Mahadevan, D. / Thanki, N. / Singh, J. / Mcphie, P. / Zangrilli, D. / Wang, L.M. / Guerrero, C. / Levine III, H. / Humblet, C. / Saldanha, J. / Gutkind, J.S. / Najmabadi-Haske, T. |
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履歴 | 登録 | 1997年11月21日 | 処理サイト: BNL |
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改定 1.0 | 1998年2月25日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年3月24日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2022年2月16日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Other カテゴリ: database_2 / pdbx_database_status ...database_2 / pdbx_database_status / pdbx_nmr_software / pdbx_struct_assembly / pdbx_struct_oper_list Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.process_site / _pdbx_nmr_software.name |
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改定 1.4 | 2024年5月22日 | Group: Data collection / カテゴリ: chem_comp_atom / chem_comp_bond |
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