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- EMDB-45801: Cryo-EM structure of bovine Fallopian tube cilia doublet microtub... -

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基本情報

登録情報
データベース: EMDB / ID: EMD-45801
タイトルCryo-EM structure of bovine Fallopian tube cilia doublet microtubule (48-nm periodicity)
マップデータ
試料
  • 細胞器官・細胞要素: bovine fallopian tube cilia
    • タンパク質・ペプチド: x 42種
  • リガンド: x 3種
キーワードaxoneme / cilia / microtubule / dynein / Fallopian tube / doublet microtubule (DMT) / STRUCTURAL PROTEIN
機能・相同性
機能・相同性情報


outer dynein arm docking complex / protein localization to motile cilium / regulation of cilium movement / outer acrosomal membrane / epithelial cilium movement involved in determination of left/right asymmetry / regulation of brood size / establishment of left/right asymmetry / 9+0 motile cilium / mucociliary clearance / sperm flagellum assembly ...outer dynein arm docking complex / protein localization to motile cilium / regulation of cilium movement / outer acrosomal membrane / epithelial cilium movement involved in determination of left/right asymmetry / regulation of brood size / establishment of left/right asymmetry / 9+0 motile cilium / mucociliary clearance / sperm flagellum assembly / manchette assembly / axonemal B tubule inner sheath / axonemal A tubule inner sheath / regulation of flagellated sperm motility / protein polyglutamylation / inner dynein arm assembly / regulation of calcineurin-NFAT signaling cascade / Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane / Cilium Assembly / Intraflagellar transport / Carboxyterminal post-translational modifications of tubulin / Sealing of the nuclear envelope (NE) by ESCRT-III / Kinesins / positive regulation of feeding behavior / Resolution of Sister Chromatid Cohesion / Mitotic Prometaphase / EML4 and NUDC in mitotic spindle formation / outer dynein arm assembly / cilium-dependent cell motility / 9+0 non-motile cilium / COPI-dependent Golgi-to-ER retrograde traffic / COPI-independent Golgi-to-ER retrograde traffic / COPI-mediated anterograde transport / 転移酵素; リンを含む基を移すもの / sperm principal piece / RHO GTPases activate IQGAPs / regulation of cilium beat frequency involved in ciliary motility / cerebrospinal fluid circulation / RHO GTPases Activate Formins / cilium movement involved in cell motility / 9+2 motile cilium / MHC class II antigen presentation / regulation of store-operated calcium entry / HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand / acrosomal membrane / regulation of cilium assembly / axoneme assembly / cilium movement / ciliary transition zone / Aggrephagy / calcium ion sensor activity / axonemal microtubule / The role of GTSE1 in G2/M progression after G2 checkpoint / Separation of Sister Chromatids / cilium organization / Loss of Nlp from mitotic centrosomes / Recruitment of mitotic centrosome proteins and complexes / Loss of proteins required for interphase microtubule organization from the centrosome / Anchoring of the basal body to the plasma membrane / AURKA Activation by TPX2 / Recruitment of NuMA to mitotic centrosomes / ciliary tip / gamma-tubulin ring complex / ciliary rootlet / manchette / Regulation of PLK1 Activity at G2/M Transition / Hedgehog 'off' state / flagellated sperm motility / UTP biosynthetic process / CTP biosynthetic process / determination of left/right symmetry / Neutrophil degranulation / positive regulation of cell motility / nucleoside diphosphate kinase activity / motile cilium / GTP biosynthetic process / AMP binding / ciliary base / regulation of neuron projection development / cerebral cortex cell migration / microtubule organizing center / regulation of cell division / mitotic cytokinesis / cellular response to UV-C / axoneme / cilium assembly / glial cell projection / spermatid development / regulation of signal transduction / alpha-tubulin binding / sperm flagellum / single fertilization / beta-tubulin binding / intercellular bridge / cytoplasmic microtubule / sperm midpiece / Hsp70 protein binding / 3'-5' exonuclease activity / centriole / acrosomal vesicle
類似検索 - 分子機能
Outer dynein arm-docking complex subunit 4 / : / Protein of unknown function DUF4541 / Cilia and flagella associated protein 90 / Protein of unknown function DUF4586 / Outer dynein arm-docking complex subunit 3 / Cilia-and flagella-associated protein 96 / Sperm-tail PG-rich repeat / DJBP, EF-hand domain / FAM183 family ...Outer dynein arm-docking complex subunit 4 / : / Protein of unknown function DUF4541 / Cilia and flagella associated protein 90 / Protein of unknown function DUF4586 / Outer dynein arm-docking complex subunit 3 / Cilia-and flagella-associated protein 96 / Sperm-tail PG-rich repeat / DJBP, EF-hand domain / FAM183 family / Sperm-tail PG-rich repeat / EF-hand domain / FAM183A and FAM183B related / Sperm-associated antigen 8 / Cilia- and flagella-associated protein 95 / NDPK7, first NDPk domain / Cilia- and flagella-associated protein 107 / : / : / : / Protein CFAP95 / ODAD1 central coiled coil region / Cilia- and flagella-associated protein 143 / Cilia and flagella associated protein 107 / Tektin / Cilia- and flagella-associated protein 276 / Sperm acrosome-associated protein 9 / : / Tektin family / Protein of unknown function (DUF3695) / Sperm acrosome-associated protein 9 / Uncharacterised protein FAM166/UPF0605 / Cilia- and flagella-associated protein 77 / Protein Flattop / Ciliary microtubule inner protein 2B-like / Cilia- and flagella-associated protein 77 / Flattop / Nucleoside diphosphate kinase 7 / Piercer of microtubule wall 1/2 / Piercer of microtubule wall 1/2 / Cilia- and flagella-associated protein 141 / Cilia- and flagella-associated protein 141 / Cilia- and flagella-associated protein 161-like domain / : / EFHB C-terminal EF-hand domain / : / Nucleoside diphosphate kinase 7 N-terminal PH domain / Meiosis-specific nuclear structural protein 1 / Cilia- and flagella-associated protein 45 / NDPK7, second NDPk domain / Cilia- and flagella- associated protein 210 / CFAP53/TCHP / Trichohyalin-plectin-homology domain / Trichohyalin-plectin-homology domain / RIB43A / RIB43A / DM10 domain / EF-hand domain-containing protein EFHC1/EFHC2/EFHB / DM10 domain / DM10 domain profile. / Domains in hypothetical proteins in Drosophila, C. elegans and mammals. Occurs singly in some nucleoside diphosphate kinases. / Enkurin domain / : / Calmodulin-binding / Enkurin domain profile. / : / CFA20 domain / Cilia- and flagella-associated protein 20/CFAP20DC / CFA20 domain / Recoverin family / Parkin co-regulated protein / Parkin co-regulated protein / EF hand / Nucleoside diphosphate kinase / Nucleoside diphosphate kinase (NDPK)-like domain profile. / Nucleoside diphosphate kinase-like domain / Nucleoside diphosphate kinase / NDK / Nucleoside diphosphate kinase-like domain superfamily / EF-hand domain pair / Armadillo/plakoglobin ARM repeat profile. / Armadillo/beta-catenin-like repeat / Armadillo/beta-catenin-like repeats / Armadillo / Tetratricopeptide repeat / TPR repeat region circular profile. / Alpha tubulin / Tubulin-beta mRNA autoregulation signal. / Beta tubulin, autoregulation binding site / Beta tubulin / TPR repeat profile. / Tubulin / Tubulin, C-terminal / Tubulin C-terminal domain / Tubulin, conserved site / Tubulin subunits alpha, beta, and gamma signature. / Tetratricopeptide repeats / Tubulin/FtsZ family, C-terminal domain / Tubulin/FtsZ-like, C-terminal domain / Tubulin/FtsZ, C-terminal
類似検索 - ドメイン・相同性
Piercer of microtubule wall 2 protein / Cilia and flagella associated protein 77 / Cilia and flagella associated protein 90 / Sperm acrosome associated 9 / EF-hand domain-containing family member C2 / Ciliary microtubule associated protein 1C / EF-hand calcium-binding domain-containing protein 6 / Outer dynein arm-docking complex subunit 4 / Parkin coregulated gene protein / Tektin-3 ...Piercer of microtubule wall 2 protein / Cilia and flagella associated protein 77 / Cilia and flagella associated protein 90 / Sperm acrosome associated 9 / EF-hand domain-containing family member C2 / Ciliary microtubule associated protein 1C / EF-hand calcium-binding domain-containing protein 6 / Outer dynein arm-docking complex subunit 4 / Parkin coregulated gene protein / Tektin-3 / Outer dynein arm-docking complex subunit 3 / Cilia- and flagella-associated protein 144 / Enkurin / Outer dynein arm-docking complex subunit 2 / Cilia- and flagella-associated protein 276 / Cilia- and flagella- associated protein 210 / Cilia- and flagella-associated protein 52 / EF-hand domain-containing protein 1 / Sperm-associated antigen 8 / EF-hand domain-containing family member B / Outer dynein arm-docking complex subunit 1 / Cilia-and flagella-associated protein 96 / Cilia- and flagella-associated protein 53 / Cilia- and flagella-associated protein 161 / Tubulin alpha-1D chain / Meiosis-specific nuclear structural protein 1 / Tektin-2 / Cilia- and flagella-associated protein 107 / Tektin-4 / Ciliary microtubule inner protein 2B / Tektin-1 / Calaxin / Cilia- and flagella-associated protein 141 / Cilia- and flagella-associated protein 95 / RIB43A-like with coiled-coils protein 2 / Cilia- and flagella-associated protein 45 / Piercer of microtubule wall 1 protein / Tubulin beta-4B chain / Protein Flattop / Nucleoside diphosphate kinase homolog 7 / Cilia- and flagella-associated protein 20
類似検索 - 構成要素
生物種Bos taurus (ウシ)
手法単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 3.52 Å
データ登録者Sun C / Zhang R
資金援助 米国, 1件
OrganizationGrant number国
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)1R01 GM138854 米国
引用ジャーナル: Nature / 年: 2025
タイトル: Structural diversity of axonemes across mammalian motile cilia.
著者: Miguel Ricardo Leung / Chen Sun / Jianwei Zeng / Jacob R Anderson / Qingwei Niu / Wei Huang / Willem E M Noteborn / Alan Brown / Tzviya Zeev-Ben-Mordehai / Rui Zhang /
要旨: Reproduction, development and homeostasis depend on motile cilia, whose rhythmic beating is powered by a microtubule-based molecular machine called the axoneme. Although an atomic model of the ...Reproduction, development and homeostasis depend on motile cilia, whose rhythmic beating is powered by a microtubule-based molecular machine called the axoneme. Although an atomic model of the axoneme is available for the alga Chlamydomonas reinhardtii, structures of mammalian axonemes are incomplete. Furthermore, we do not fully understand how molecular structures of axonemes vary across motile-ciliated cell types in the body. Here we use cryoelectron microscopy, cryoelectron tomography and proteomics to resolve the 96-nm modular repeat of axonemal doublet microtubules (DMTs) from both sperm flagella and epithelial cilia of the oviduct, brain ventricles and respiratory tract. We find that sperm DMTs are the most specialized, with epithelial cilia having only minor differences across tissues. We build a model of the mammalian sperm DMT, defining the positions and interactions of 181 proteins including 34 newly identified proteins. We elucidate the composition of radial spoke 3 and uncover binding sites of kinases associated with regeneration of ATP and regulation of ciliary motility. We discover a sperm-specific, axoneme-tethered T-complex protein ring complex (TRiC) chaperone that may contribute to construction or maintenance of the long flagella of mammalian sperm. We resolve axonemal dyneins in their prestroke states, illuminating conformational changes that occur during ciliary movement. Our results illustrate how elements of chemical and mechanical regulation are embedded within the axoneme, providing valuable resources for understanding the aetiology of ciliopathy and infertility, and exemplifying the discovery power of modern structural biology.
履歴
登録2024年7月18日-
ヘッダ(付随情報) 公開2024年10月30日-
マップ公開2024年10月30日-
更新2025年3月19日-
現状2025年3月19日処理サイト: RCSB / 状態: 公開

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構造の表示

添付画像

emd_45801.png

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マップ

ファイルダウンロード / ファイル: emd_45801.map.gz / 形式: CCP4 / 大きさ: 512 MB / タイプ: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
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画像のコントロール

大きさ
明度
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軸Z (Sec.)Y (Row.)X (Col.)
1.34 Å/pix.
x 512 pix.
= 686.08 Å		1.34 Å/pix.
x 512 pix.
= 686.08 Å		1.34 Å/pix.
x 512 pix.
= 686.08 Å

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画像は Spider により作成

ボクセルのサイズX=Y=Z: 1.34 Å
密度

ヒストグラム

ヒストグラム (対数)
表面レベル登録者による: 0.3
最小 - 最大0.0 - 2.5421329
平均 (標準偏差)0.0112885395 (±0.07833449)
対称性空間群: 1
詳細

EMDB XML:

マップ形状
Axis orderXYZ
Origin000
サイズ512512512
Spacing512512512
セルA=B=C: 686.08 Å
α=β=γ: 90.0 °

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添付データ

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マスク #1

ファイルemd_45801_msk_1.map
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ハーフマップ: #2

ファイルemd_45801_half_map_1.map
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ハーフマップ: #1

ファイルemd_45801_half_map_2.map
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試料の構成要素

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全体 : bovine fallopian tube cilia

全体名称: bovine fallopian tube cilia
要素
  • 細胞器官・細胞要素: bovine fallopian tube cilia
    • タンパク質・ペプチド: Armadillo repeat containing 4
    • タンパク質・ペプチド: Coiled-coil domain containing 114
    • タンパク質・ペプチド: Coiled-coil domain containing 173
    • タンパク質・ペプチド: Uncharacterized protein C1orf158 homolog
    • タンパク質・ペプチド: Protein Flattop
    • タンパク質・ペプチド: CFAP141
    • タンパク質・ペプチド: Cilia and flagella associated protein 161
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 20
    • タンパク質・ペプチド: EF-hand domain family member B
    • タンパク質・ペプチド: CFAP276
    • タンパク質・ペプチド: Cilia and flagella associated protein 45
    • タンパク質・ペプチド: Cilia and flagella associated protein 52
    • タンパク質・ペプチド: Methyl-CpG binding domain protein 1
    • タンパク質・ペプチド: Cilia and flagella associated protein 77
    • タンパク質・ペプチド: CFAP95
    • タンパク質・ペプチド: Cilia-and flagella-associated protein 96
    • タンパク質・ペプチド: EF-hand calcium-binding domain-containing protein 1
    • タンパク質・ペプチド: EF-hand calcium binding domain 6
    • タンパク質・ペプチド: EF-hand domain containing 1
    • タンパク質・ペプチド: EFHC2
    • タンパク質・ペプチド: Enkurin, TRPC channel interacting protein
    • タンパク質・ペプチド: Protein FAM166B
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 144
    • タンパク質・ペプチド: Meiosis-specific nuclear structural protein 1
    • タンパク質・ペプチド: Nucleoside diphosphate kinase 7
    • タンパク質・ペプチド: Outer dynein arm-docking complex subunit 3
    • タンパク質・ペプチド: PACRG protein
    • タンパク質・ペプチド: Pierce1
    • タンパク質・ペプチド: Pierce2
    • タンパク質・ペプチド: RIB43A-like with coiled-coils protein 2
    • タンパク質・ペプチド: Sperm acrosome associated 9
    • タンパク質・ペプチド: Tektin-1
    • タンパク質・ペプチド: Tektin-2
    • タンパク質・ペプチド: Tektin-3
    • タンパク質・ペプチド: Tektin-4
    • タンパク質・ペプチド: TTC25 protein
    • タンパク質・ペプチド: Ciliary microtubule associated protein 1A
    • タンパク質・ペプチド: Ciliary microtubule associated protein 1C
    • タンパク質・ペプチド: Cilia and flagella associated protein 90
    • タンパク質・ペプチド: Sperm associated antigen 8
    • タンパク質・ペプチド: Tubulin beta-4B chain
    • タンパク質・ペプチド: Tubulin alpha-1D chain
  • リガンド: GUANOSINE-5'-DIPHOSPHATE
  • リガンド: MAGNESIUM ION
  • リガンド: GUANOSINE-5'-TRIPHOSPHATE

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超分子 #1: bovine fallopian tube cilia

超分子名称: bovine fallopian tube cilia / タイプ: organelle_or_cellular_component / ID: 1 / 親要素: 0 / 含まれる分子: #1-#42
由来(天然)生物種: Bos taurus (ウシ)

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分子 #1: Armadillo repeat containing 4

分子名称: Armadillo repeat containing 4 / タイプ: protein_or_peptide / ID: 1 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 116.01707 KDa
配列文字列: MGVALTRSAQ WTAAGHGAKT LEVTPLNEAI VKEIIMFVES FIYKYPQEAN YVFVEPLEWK TNLDPSAFGS GYAVSGTTVK SEEADKNGE PLLYLSVPQI KIRSFGQLSR MLYIAKNMKL KEAQACIEAN RNPVAKILGL DYNIISEKIG NSFVSNILDK I TKDDDSES ...文字列:
MGVALTRSAQ WTAAGHGAKT LEVTPLNEAI VKEIIMFVES FIYKYPQEAN YVFVEPLEWK TNLDPSAFGS GYAVSGTTVK SEEADKNGE PLLYLSVPQI KIRSFGQLSR MLYIAKNMKL KEAQACIEAN RNPVAKILGL DYNIISEKIG NSFVSNILDK I TKDDDSES EIKMKIALQL KQLDLHLLNH SLKHISLEIR LNPGTVKNDI ELLKQFSGKG KQTVLESIEY TSDYEFSNGC RA PPWRQIK GEICYVLVKP HDAETLCVTC SKEGVFLNGG KTDDEGQINY ERKGEIYKDL VTLLKEKSAI FSENMSKQEI KFS EQPQKD QPNEAPKEEV AITHKASVTS RKSTQEKNRI NLGRSQLTKR LEPSLNWRTS VSSKDRNTLR DTQVEKHGGK LEKS RSSVS PGRAQLIRKS VEKIEEIISD SSSESEEDEE QPDHRQEANA DLPSEYWQIQ KLVKYLKGGN QTATVIALCS MKDFN LAQE TCQLAIRDVG GLEVLINLLE TDEVKCKIGS LKILKEISHN PQIRRNIVDL GGLPVMVNIL DSPHKSLKCL AAETIA NVA KFRRARRVVR RHGGITKLVA LLDCGKHSGE PAQSSLYETR DVEVARCGAL ALWSCSKSYA NKEAIRKAGG IPLLARL LK TSHENMLIPV VGTLQECASE ENYRAAIKAE RIIENLVKNL NSENEQLQEH CAMAIYQCAE DEETRDLVRL HGGLKPLA S LLNNTDNKER LAAVTGAIWK CSISKENVTK FREYKAIETL VGLLTDQPEE VLVNVVGALG ECCQEHENRV IIRRCGGIQ PLVNLLVGIN QALLVNVTKA VGACAVEPES MMIIDRLDGV RLLWSLLKNP HPDVKASAAW ALCPCIQNAK DAGEMVRSFV GGLELVVNL LKSDNKEVLA SVCAVITNIA KDQENLAVIT DHGVVPLLSK LANTNNDKLR RHLAETISRC CMWGRNRVAF G EHKAVAPL VRYLKSNDTN VHRATAQALY QLSEDADNCV TMHENGAVKL LLDMVGSPDE ELQEAAAGCI SNIRRLALAI EK ARYS

UniProtKB: Outer dynein arm-docking complex subunit 2

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分子 #2: Coiled-coil domain containing 114

分子名称: Coiled-coil domain containing 114 / タイプ: protein_or_peptide / ID: 2 / コピー数: 3 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 77.675969 KDa
配列文字列: MPFGLSAGST RSEDGSEAFL EGMVDWELSR LQRQCKVMED ERRAYSKEVH QRINKQLEEI QRLEGVRHKL RVQISIAQSQ VRRLRDSER LESMGHLLKC QVRVQAEVKE LQAQNQALDR EIQEWESRNS AHSKNARSPG CVQHDKVKSQ RRIKSLENQL D KVICRFDI ...文字列:
MPFGLSAGST RSEDGSEAFL EGMVDWELSR LQRQCKVMED ERRAYSKEVH QRINKQLEEI QRLEGVRHKL RVQISIAQSQ VRRLRDSER LESMGHLLKC QVRVQAEVKE LQAQNQALDR EIQEWESRNS AHSKNARSPG CVQHDKVKSQ RRIKSLENQL D KVICRFDI QLAQNATLRE ELDLLRIERN RYLNVDRKLQ KEIQLLKDSV RNLMVSSTSA YTVREEAKAK LGMLRERAEK EV AQNETEV QILQRQIAHL EQLHHFLKLK NGDRQPDSAI VEKREQRARE VAEGLRKTSQ EKLVLRYEDA LNKLSQMTGE SDP DLLVEK YLELEERNFA EFNFINEQNS ELEHLQEEIK EMQEALVSGR RSEEDRRAQQ EQQRAELQQR VDDVHSEADD LEAR YHNFR EQLEKLKTNI QHLFTRAQCD STLINDLLGI KTHMRDRDIS LFLSLIEKRL VQLLTVQAFL ETQVVVMFNA ALMVL GQSS EDFPKKVAPP QPPDNLEDPP GFEAKDDYPL SKEELLSSVM KAEQHLKELV ESIKVESTPS MTSSTQKVSS SSRLVT QRP SQVPGSIMSH RTSGILVSSG GRATSSNVGH VTFGDSSATT GGLMSSRGSI PGRVTFRSPN SSSYLGSTGY VGSSRDH DS FEASKGPGSE SSGGLGSSPG PASSPGPASS TGQASSTSKD SQSNY

UniProtKB: Outer dynein arm-docking complex subunit 1

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分子 #3: Coiled-coil domain containing 173

分子名称: Coiled-coil domain containing 173 / タイプ: protein_or_peptide / ID: 3 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 65.437598 KDa
配列文字列: MLVRFGRRSG QAKESAEMKN CEEDPVLYPP LLPTKVDLRQ VTIIPHNEWE RIRDSLDSLT REAACLRAER KAKKEMHLRS QEVVKHWTN TYAGMKEQKL EAKKKRDEEI EAERQILDIE EAIYKQGERK KAIELAKQYQ FYQTERVKNF HSGLLLSRVM K ERDAQIEF ...文字列:
MLVRFGRRSG QAKESAEMKN CEEDPVLYPP LLPTKVDLRQ VTIIPHNEWE RIRDSLDSLT REAACLRAER KAKKEMHLRS QEVVKHWTN TYAGMKEQKL EAKKKRDEEI EAERQILDIE EAIYKQGERK KAIELAKQYQ FYQTERVKNF HSGLLLSRVM K ERDAQIEF QKSKIKSDKK WEEQVKLNVE KAFKEEREKA EKQRRERVAL AKDHLKQIKE HEEEEERRRK EEEKDAEEIK RQ NSLYEIE MKKKQGKKKE EINESRRLFF EHLNDKHIIK AVEQQQQEEE DEKIRKFIKA KKRLTQMGKE KEAETHRLME ERR KRINNF LSKLMKEKFD NEDLIIARDI AEAEAEWEKR EREKYEKNKA ELKAIAEHRA LVMKNKEEEE RQRKIEATEQ MLAI LKADQ IFWEHEKEKK QKADKERREV QDAHIQQMAK HKFNALQAKQ AESEYCRLTE ALVAEKEKEF QDYAREVIES ESEST KKYI YPLVKAVQEG PGGGRGPVLV DRGGLRPSYQ ANDTTGVQLP FYNSPGSKYN NFQKSKGRLG FTW

UniProtKB: Cilia- and flagella- associated protein 210

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分子 #4: Uncharacterized protein C1orf158 homolog

分子名称: Uncharacterized protein C1orf158 homolog / タイプ: protein_or_peptide / ID: 4 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 23.271453 KDa
配列文字列: MQFLTAVSPQ SSSTPSWKIE TKYSTRVLTG NWTEERRKFI KATEKTPQTI YRKEYVPFPG HRPDQISRWY SKRTVEGLPY KYLITHHQE PSQRYLISTY DDHYNRHNYH PGLPELRTWN RHKLLWLPEK ADFPLLGPPT NYGLYEQLKQ KWLPPPEATL R ESIYTSSY ...文字列:
MQFLTAVSPQ SSSTPSWKIE TKYSTRVLTG NWTEERRKFI KATEKTPQTI YRKEYVPFPG HRPDQISRWY SKRTVEGLPY KYLITHHQE PSQRYLISTY DDHYNRHNYH PGLPELRTWN RHKLLWLPEK ADFPLLGPPT NYGLYEQLKQ KWLPPPEATL R ESIYTSSY PRPPAGAMSR REHAIPVPPP RLQPVPHF

UniProtKB: Cilia- and flagella-associated protein 107

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分子 #5: Protein Flattop

分子名称: Protein Flattop / タイプ: protein_or_peptide / ID: 5 / コピー数: 3 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 21.214035 KDa
配列文字列: MATNYSANQY EKPFSPKYLQ NWSLAKPTKE RISSHEGYTQ IIANDRGHLL PSVPRSKASP WGSFMGTWQM PLKVPPARAT LTSRTAAGA ASLTRWIQKN PDLLKASNGL RPEIFGKPHD PDSQKKLRKS ITKTVQQAPS PTIIPSSPAS NLSSPDQLQS S HPSAGHTP ...文字列:
MATNYSANQY EKPFSPKYLQ NWSLAKPTKE RISSHEGYTQ IIANDRGHLL PSVPRSKASP WGSFMGTWQM PLKVPPARAT LTSRTAAGA ASLTRWIQKN PDLLKASNGL RPEIFGKPHD PDSQKKLRKS ITKTVQQAPS PTIIPSSPAS NLSSPDQLQS S HPSAGHTP GPQSPLNSPK CPPGSPCLPH AGRNLAEV

UniProtKB: Protein Flattop

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分子 #6: CFAP141

分子名称: CFAP141 / タイプ: protein_or_peptide / ID: 6 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 12.361437 KDa
配列文字列:
MSMEKMGKVE EHFQRALELK KMVHRWRNSH THCLWQITLS QRRNPYAILR MQDTMVQELA LANKQLLMVR QAALHQLFEK EHQQYQQEL NEKGKAFYME RL

UniProtKB: Cilia- and flagella-associated protein 141

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分子 #7: Cilia and flagella associated protein 161

分子名称: Cilia and flagella associated protein 161 / タイプ: protein_or_peptide / ID: 7 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 36.519594 KDa
配列文字列: MAQNLYGPRV RIGNWNEDVY LEEEIMKDFL AKRDKGQLLI QRNRRLKENL LRPMQLSVSE DGYIHYGDKV MLVSPDHPET EADLFLPGD LSLCMTPDEI KAHLSNELEV PCGLSAAQTK IPVGRNTFTI LCAAGEVIGQ VLRYGQNFRL GITGGFDDRM L YLSSDHRT ...文字列:
MAQNLYGPRV RIGNWNEDVY LEEEIMKDFL AKRDKGQLLI QRNRRLKENL LRPMQLSVSE DGYIHYGDKV MLVSPDHPET EADLFLPGD LSLCMTPDEI KAHLSNELEV PCGLSAAQTK IPVGRNTFTI LCAAGEVIGQ VLRYGQNFRL GITGGFDDRM L YLSSDHRT LLKSSKRSWL QEVFLTHEDS YLNCWQAAFP HPQLRLEYEG SPVPANTKIL ITHCHTNRGL VAHRHLFLRT YF GQEAEVA AHTYLDSHRV EKPKNHWMLV TGAPRKDLST MLDLPKPPAE DTRALEQERE QVSDPGARST PDARGCVPQC TLP M

UniProtKB: Cilia- and flagella-associated protein 161

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分子 #8: Cilia- and flagella-associated protein 20

分子名称: Cilia- and flagella-associated protein 20 / タイプ: protein_or_peptide / ID: 8 / コピー数: 6 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 22.781389 KDa
配列文字列: MFKNTFQSGF LSILYSIGSK PLQIWDKKVR NGHIKRITDN DIQSLVLEIE GTNVSTTYIT CPADPKKTLG IKLPFLVMII KNLKKYFTF EVQVLDDKNV RRRFRASNYQ STTRVKPFIC TMPMRLDDGW NQIQFNLSDF TRRAYGTNYI ETLRVQIHAN C RIRRVYFS ...文字列:
MFKNTFQSGF LSILYSIGSK PLQIWDKKVR NGHIKRITDN DIQSLVLEIE GTNVSTTYIT CPADPKKTLG IKLPFLVMII KNLKKYFTF EVQVLDDKNV RRRFRASNYQ STTRVKPFIC TMPMRLDDGW NQIQFNLSDF TRRAYGTNYI ETLRVQIHAN C RIRRVYFS DRLYSEDELP AEFKLYLPVQ NKAKQ

UniProtKB: Cilia- and flagella-associated protein 20

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分子 #9: EF-hand domain family member B

分子名称: EF-hand domain family member B / タイプ: protein_or_peptide / ID: 9 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 97.960547 KDa
配列文字列: MCSFLRVPSP KGLEPSKGLG APLQPGTAYP SEMSALGPGM TVSGRKSPLS MEVGLAPEGK DDLEERRVFM GTTSPTELGL RVGLRKDFP CSKTYEERMA SPEIRSPSSK GLELRLKRQN ISRTVMDGSN LGVHRVSASQ ETKPPLSALP GRVGLEKERF L AGYCPGRV ...文字列:
MCSFLRVPSP KGLEPSKGLG APLQPGTAYP SEMSALGPGM TVSGRKSPLS MEVGLAPEGK DDLEERRVFM GTTSPTELGL RVGLRKDFP CSKTYEERMA SPEIRSPSSK GLELRLKRQN ISRTVMDGSN LGVHRVSASQ ETKPPLSALP GRVGLEKERF L AGYCPGRV TQPPLGQGCE SPQASGGRRC PVTGDPEGFG ASVSKLPALG MECRGELGGE SACVVMKPRA ETEPPVEVDM GL TRLEEPA EMESPEPQMG LVMEPPAWQL AQQPEEQREA ENTEPGVEPP DRIRPIYSGK FFDRMPCWPS AGKVLPIGYR AAT CLTERF PRLMTPPEAK KFFNFRYPPA GAERVFYGRA NDPQIAPSLT HGIRSKISIP AKVLINPQPI TTFQQKMKDK KESV YFSNQ RAPLGKSHDQ TPGLPKGLDI LNTTFGTAIV RETSARDMVN PPKPYKEVFE EAQAGHDLYV VSHNDYFVGE AKNRK YDPS SFHRFNLYGI PTPHFNDGRN MAKTLHWLHE LQMKRGAKIV SKRVDDFKEK FQHRLGRVLD PIAETMNVPP DYTFGA FLR PEDYGVGDLI HRRLPGEYLR GKDRQRGLVA AVRHHLKKVN YQNFDTLLAA FRHYDKKGDG VIDRAELQEA CDQACLH LD EKLLDQLFEY CDVDKDGLIN YLEFANFLTW KDKTPLKEYE ERVLIKGRKA DCANPAEANV EESEPALLLK PEDIVLKE P GSSEKTLRTL LRPSDKVSNH YKTTSSEISA VVGAVPSTCY PTYGVPTIRS DIPAPLIRRV SDRTSYGEEG NAYSLLHPT IFAQKGVFER DFFKTRSKQE ISEILCNIGV KLSEDEFENV WNLASKKHHR GEVCVENIRS VLDELQHADG AKCKAAT

UniProtKB: EF-hand domain-containing family member B

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分子 #10: CFAP276

分子名称: CFAP276 / タイプ: protein_or_peptide / ID: 10 / コピー数: 3 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 19.387805 KDa
配列文字列:
MPLTRDPFQN PALDKDDSYL GKSRASKKLP YKNPTHLAQQ QEPWCRLSST PTITSMKRDG FFFYSEIPKD DLDFRLAALY NHHTGTFKN KSEILTHQET IQDTRRIKTQ FPGEFLPAPQ PPLITSRANI RHWINPKKES IHSIQGSIVS PHTAATNGGY S RKNDGGFF ST

UniProtKB: Cilia- and flagella-associated protein 276

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分子 #11: Cilia and flagella associated protein 45

分子名称: Cilia and flagella associated protein 45 / タイプ: protein_or_peptide / ID: 11 / コピー数: 4 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 65.800328 KDa
配列文字列: MPLSTAGVLS SASTASNRSR NRPRYRTKAL SSEVDESLFG AIKPLTRSDS PIVLLRDKHA IRKTLTALGL DHKPETIQLI TRDMVRELI IPTKDPSGQS LIMSPEEFER IKWASHVLTK EELEAREQAF KKEKEAIVDT VTTRKKIMKQ KEMVWRNNRK L SDLEEVAK ...文字列:
MPLSTAGVLS SASTASNRSR NRPRYRTKAL SSEVDESLFG AIKPLTRSDS PIVLLRDKHA IRKTLTALGL DHKPETIQLI TRDMVRELI IPTKDPSGQS LIMSPEEFER IKWASHVLTK EELEAREQAF KKEKEAIVDT VTTRKKIMKQ KEMVWRNNRK L SDLEEVAK ERAQNLLQRA NQLRMEQEEE LKDMKKIILN AKCHAIRDAQ ILEKQLIQKE LDAEEKRLDQ MMEVERQKSV QR QEELDRK RREERIRGRR HIVEQMEKNQ EERSLLAEQR EQEKEQMLEY MEKLQEEDLR DLEQRHQQKL KMQAEIKRIN DEN QRQKAE LLAQEKLADQ MVMEFTKKKM AREAEFEAEQ ERIRREKEKE IARLRAMQEK AQDYQAEQDA LRAKRNQEVA DREW RRKEK ENAQKKMETE AKLRKSRLEQ VAFKEHTLAV QVQRDRDEFE RILRAQREQI EKERLEEEKK ATGRLQHANE LRRQV RENQ QKQVQARIAT FDEGRRLKEE AQKRRERIED IKRKKLEELR ATGLPEKYCI EAERKANIPV NTSVN

UniProtKB: Cilia- and flagella-associated protein 45

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分子 #12: Cilia and flagella associated protein 52

分子名称: Cilia and flagella associated protein 52 / タイプ: protein_or_peptide / ID: 12 / コピー数: 3 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 68.719602 KDa
配列文字列: METQASPKDE VAEAVELELE AVIGFNGHVP TGLKCHPDQE HLVYPLGCTI LIQAINTQEQ NFLHGHGNNV SCVAISKSGL YIASGQVTF MGFKADIILW DYKKRELMAR LSLHKGKIEA LAFSPNDMYL VSLGGPDDGS VVVWSIAKRE AICGSPAAGL N VGNATTVI ...文字列:
METQASPKDE VAEAVELELE AVIGFNGHVP TGLKCHPDQE HLVYPLGCTI LIQAINTQEQ NFLHGHGNNV SCVAISKSGL YIASGQVTF MGFKADIILW DYKKRELMAR LSLHKGKIEA LAFSPNDMYL VSLGGPDDGS VVVWSIAKRE AICGSPAAGL N VGNATTVI FSKCRDEMFV TAGNGTIRVW ELDLPNRKIW PTECQTGQMK RIVMSISMAN DDSFFYLGTT TGDILKMNPR TK LLADTGP AKDKFSLGVS AICCLKMGGL LVGSGDGLLV FCKSPSYKPI KKIQLQGGIT SITLRGEGHQ FFVGTEESHI YRV NFTNFK ETLITTCHFE SVEDIVFPFG TAELFATCAK KDIRVWHTLT NRELLRITVP NMTCHGIDFM RDGKSIISAW DDGR IRAFA PETGRLMYVI NNAHRIGVTA IATTSDCKRV ISGGGEGEVR VWHIGHQTQK LEEALKEHKS SVSCIRVKKS NEECV TAST DGTCIIWDLV RLRRNQMILA NTLFQCVCYH PEEFQIITSG TDRKIAYWEV FDGSVIRELD GSLSGAVNGM DITVEG VHF VTGGNDHLVK VWDYNEGEVT HVGVGHSGNI TRIRISPGNQ YIVSVSADGA ILRWKYPFPS

UniProtKB: Cilia- and flagella-associated protein 52

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分子 #13: Methyl-CpG binding domain protein 1

分子名称: Methyl-CpG binding domain protein 1 / タイプ: protein_or_peptide / ID: 13 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 62.138992 KDa
配列文字列: MYSQRFGIVQ REVKGPTPKV VIVRAKPPKG QGAEHHLQRI QHSHQKHHAI LASIKSIERD RLKTEWDQHN DCKFVDSLVK ARVKDAMQG FIINTEERRN KLRELLASEE NEYFTEMQLK EETIEEKKDR MRDKIRLLRE KKEKERQDFV AEKLDQQFRE R CQELRAEL ...文字列:
MYSQRFGIVQ REVKGPTPKV VIVRAKPPKG QGAEHHLQRI QHSHQKHHAI LASIKSIERD RLKTEWDQHN DCKFVDSLVK ARVKDAMQG FIINTEERRN KLRELLASEE NEYFTEMQLK EETIEEKKDR MRDKIRLLRE KKEKERQDFV AEKLDQQFRE R CQELRAEL FCIHQKAVCE ERKAQIAFNE ELKRQKVVEE QMFSKLWEED RLAKERREAK EERRQKELVE NTRLGLNAQV TS IQAQRQA AQRLKEEEAL LVENENAQVK LENEQDKLKK QKTKQEIRAA LQKALQEKME RMQQEYREEQ DLNMKLMQNA LQS LQEETD KKKQKKEDMR REQKIYYQYL AQRHEEEKAQ EKELDRMLEK EKEKKFAEKD KELRLEKEAR KQLLNEVMCT RKLQ VQEKL QRKAKEQEER TMEQERINEG LKELNCEERE NFIRRCSLAQ EYRKQLQMQI CSQQQAREAE EEEERREFEA GIAAE KSFQ DKIQGILSTH QVVPRNIHPM RRACSTKLPP

UniProtKB: Cilia- and flagella-associated protein 53

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分子 #14: Cilia and flagella associated protein 77

分子名称: Cilia and flagella associated protein 77 / タイプ: protein_or_peptide / ID: 14 / コピー数: 4 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 32.999203 KDa
配列文字列: MPEARNSCQD LTRWKKKKPP VRRTVSQICP PPRRPLTVAD IRPGMENERL GVVRDSMFQN PLIVKAELGK PRERSCSLPG INFNYGLYI RGLDGGVPEA IGHWNVFKQQ PTCPHELTRN YIAMNRGAVK AGLVTARENL HYRQLNDIRI SDQDDRRLKK E PPSLPPNM ...文字列:
MPEARNSCQD LTRWKKKKPP VRRTVSQICP PPRRPLTVAD IRPGMENERL GVVRDSMFQN PLIVKAELGK PRERSCSLPG INFNYGLYI RGLDGGVPEA IGHWNVFKQQ PTCPHELTRN YIAMNRGAVK AGLVTARENL HYRQLNDIRI SDQDDRRLKK E PPSLPPNM TFGIRARPST PFFDLLQHRY QQLWVQEQKD TQKAIKLEKK HKVILGKLYE TRSSQLRKYK PPMGLDTLWH MP HFQKVGP HLATFPTEAD RQRAFKAHRE ECAVRQGTLR MGNYTHP

UniProtKB: Cilia and flagella associated protein 77

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分子 #15: CFAP95

分子名称: CFAP95 / タイプ: protein_or_peptide / ID: 15 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 26.661025 KDa
配列文字列: MDSSDSSCQE WCSHGQYWLE LGPTDLMERK GSLTLRSHHK KYSKPVLVYS WHRDRETYPK DYDIEGPEEV KKLCNSTYRR LGTSEPPVW ISETREKMAQ VCLNTKLAKI KSKALLNEET MNSGIIERDT GLPATGFGAL FTRHSPDWSK MCTLTTYAEE Y APPYEYQP ...文字列:
MDSSDSSCQE WCSHGQYWLE LGPTDLMERK GSLTLRSHHK KYSKPVLVYS WHRDRETYPK DYDIEGPEEV KKLCNSTYRR LGTSEPPVW ISETREKMAQ VCLNTKLAKI KSKALLNEET MNSGIIERDT GLPATGFGAL FTRHSPDWSK MCTLTTYAEE Y APPYEYQP LGDPCQDDDY SIVHRKCRSQ FTDLDGSKRV GINTWHDESG IYANSYVKRK LYSLTGGPIA PFLK

UniProtKB: Cilia- and flagella-associated protein 95

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分子 #16: Cilia-and flagella-associated protein 96

分子名称: Cilia-and flagella-associated protein 96 / タイプ: protein_or_peptide / ID: 16 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 34.554371 KDa
配列文字列: MPAEGGKTDM ERIGLFSEME YITVGDKYVS QFNRPFNESA SKNRQILPGG SKEMSNLQAG YFDPHFVRIF EGESYVNPNQ VRRRYMMEE AKKNLSKAFL PSNGEKKPCG LGSYYGTIGG PVPFFSAQSK PKEKYEPPGK NLYTNPGKKG TGYGYANITI G KQFSHSSD ...文字列:
MPAEGGKTDM ERIGLFSEME YITVGDKYVS QFNRPFNESA SKNRQILPGG SKEMSNLQAG YFDPHFVRIF EGESYVNPNQ VRRRYMMEE AKKNLSKAFL PSNGEKKPCG LGSYYGTIGG PVPFFSAQSK PKEKYEPPGK NLYTNPGKKG TGYGYANITI G KQFSHSSD LYDAAKLNNK KENEEHRRLL KGTAFKLNLY PREYFDTNPY MSEKPLPPIK KVEKKETVGN PFKPSSPGKK AG GMKAGTF DPYPSHSADP YVVKLKSPSS KSAKVFHPPG GPKSRPIESI MALNVKRALN MKNYKTASVQ SY

UniProtKB: Cilia-and flagella-associated protein 96

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分子 #17: EF-hand calcium-binding domain-containing protein 1

分子名称: EF-hand calcium-binding domain-containing protein 1 / タイプ: protein_or_peptide / ID: 17 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 24.667131 KDa
配列文字列: MNRKKLQKLT DSLTKNCKHF SKFEVKCLIN LFYNLVGEVT ERQGVIIGLD RNAFRNILHM TFGMTDDMIM DRVFRGFDKD NDGCISVTE WVYGLSVFLR GTLEEKMKYC FEVFDLNGDS FISKEEMFHM LKNSLLKQPS EEDPDEGIKD LVEITLKKMD H DHDGKLSF ...文字列:
MNRKKLQKLT DSLTKNCKHF SKFEVKCLIN LFYNLVGEVT ERQGVIIGLD RNAFRNILHM TFGMTDDMIM DRVFRGFDKD NDGCISVTE WVYGLSVFLR GTLEEKMKYC FEVFDLNGDS FISKEEMFHM LKNSLLKQPS EEDPDEGIKD LVEITLKKMD H DHDGKLSF ADYEQAVREE TLLLEAFGPC LPDPKSQSEF EAQVFKDPNE FNEV

UniProtKB: Calaxin

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分子 #18: EF-hand calcium binding domain 6

分子名称: EF-hand calcium binding domain 6 / タイプ: protein_or_peptide / ID: 18 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 162.942844 KDa
配列文字列: MTVTKSELRR VITTFLLPLT REQFQDVLAQ IPLTSSGAVP YLVFLSRFGG IDLNINVIKR GGENEMNGCR TLKDLEAQVG EKIFKNIKT VIKALMLIDV NTTGLVQPHE LRRVLETFCL KMKDEEYKKF AQHYNIDKDA AVDYNVFLKN LGSNNDLNLK Y NMGSQEVL ...文字列:
MTVTKSELRR VITTFLLPLT REQFQDVLAQ IPLTSSGAVP YLVFLSRFGG IDLNINVIKR GGENEMNGCR TLKDLEAQVG EKIFKNIKT VIKALMLIDV NTTGLVQPHE LRRVLETFCL KMKDEEYKKF AQHYNIDKDA AVDYNVFLKN LGSNNDLNLK Y NMGSQEVL WENQRVKSFK REEPPSSAVS DNIWKNYSLD EIETAFCLEL SKCYEKVEKA LSAGDPCTSG YVSLNYLKIV LD TFVYRLP RRIFIQLMKR FGLKTTTKVN WKQFLTSFYE PQYEASSKAP LTKRNSINFR NQVHKENVIT KLFRHEDHDS SLK KALLLI KSKPDGQITG QELQRILNCM VVKISDSEFR ELMRILDPGC TGCVNVSRFI ELIEESPKLH KIPAYKDTKM PLFL AWDSV EEIIHDSIAK NLSAFCNMLR SYDLGDTGLI GRNNFKKIMR VFCPFLTTEH LVKLCSKFQD IASGRILYKK LLACL GINR PPTVSPVSMP KGQLLNEHLQ KEEQPLPDHS ERATPAESQG AVTRNMTKDE VIEKLKSCIQ QQDPAFRKRF LDFTKE PNG KIHTHDFKKV LEDYGMPMDD DQYALLTTKL GYKKEGMSYL DFAAGFEDPK MNEPEVTPPQ TPVLPKGDVD SFFVTAE EC LRQFPRRLKE FFRDPYAAFF KMDTDRDGIL TMHDLHRLLQ HLLFNLKDEE FERLLGLLGL RLSITLNFRE FRNLCEKR S FSADDDAPQR LPRPKQKVAD SELACEQAHQ YLVTKAKTRW SDLSKNFIET DSEGNGILRR RDMKNALYGF DIPLTPREF EKLWMRYDSE GRGHITYQEF LQKLGINYSA DIHRPYAEEY FNFMGHFTKP QQVQEELKEL QQSTEKAMPA RDKLKDHDQD ISKALAKLD KSRTGYISLG RLQRLLQECG CSLKEEELID LLNSWGIAWH NNSINYLDFL RAVENNKLTR PQSQEKEESV P INFAALSP EEVLKNIQGV IAASSLALST AFSALDKEDT GFVKASDFGQ VLKDFCYKLT DNQYHYFLRK LRLHLTPYIN WK YFLQNFS SYVEETAVEW AEKMPRGPRP LSPKEMANQE LLARLHKAVT SHYHAIAQEF ENFDTMKTNT ASRDEFRSIC TRH VQVLTD EQFDRLWEEM PVNSKGRLRY LDFLSSFNVD KQATPLATSD SAKAQRGSSV PEVSDRGRSA GSSPTRDPKA GSKP RSHPC TPSSVSGTPP LQNCEPIETK LRKKVQGCWR ELLRECKERD FNKQGEIPGP EFLALVEKFN LDISRDECQQ LLIKY DLKN NGKFAYCSFI QSCVLLLKAK ETSLMQRMKI QNANKMKEAG AETCSFYSAL LRIQPKIVHC WRPMRRTFKA YDEGGT GLL SVADFRKVLR QYSINLSEEE FFHILEYYDK TLSSKISYND FLRAFLQ

UniProtKB: EF-hand calcium-binding domain-containing protein 6

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分子 #19: EF-hand domain containing 1

分子名称: EF-hand domain containing 1 / タイプ: protein_or_peptide / ID: 19 / コピー数: 3 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 74.125344 KDa
配列文字列: MVSNPVHGLP FLPGTSFKDL TKTAFHRSQT LGYRNGYAVV RRPTVGIGGD RLQVNQLSQA DLDELASKIP ILTYGQARQA PPAAFVPAH VAFDKKVLKF DAYFQEDVPM SIEEHYRIRQ VHIYYYLEDD SMSVIEPVVE NSGIPQGKLI KRQRLSKNDR G DHYHWKDL ...文字列:
MVSNPVHGLP FLPGTSFKDL TKTAFHRSQT LGYRNGYAVV RRPTVGIGGD RLQVNQLSQA DLDELASKIP ILTYGQARQA PPAAFVPAH VAFDKKVLKF DAYFQEDVPM SIEEHYRIRQ VHIYYYLEDD SMSVIEPVVE NSGIPQGKLI KRQRLSKNDR G DHYHWKDL NRGINITIYG KTFRIVDCDK FTQVFLESQG IELNPPEKMA LDPYTELRKQ PLRKYVTPTD FDQLKQFLTF DK QVLRFYA IWDDTDSMFG ECRTYIIHYY LMDDTVEIRE VHERNDGRDP FPLLMNRQRM PKVLVENAKN FPRCVLEISD KEV LEWYTA KDFIVGKPLT ILGRTFFIYD CDPFTRQYYQ EKFGISDLPR IDMSKKEPPP MKQELPPYNG FGLIEDSAQN CFAL IPKAP QKDVIKMLMN ENKVLRYLAT LESPFPEDKG RRFVLSYFLA TDMISIFEPP VRNSGIIGGK YLGRTKVVKP GSSVE NPVY YGPSDFFIGA VIEVFGHRFV ILDTDDYVLK YMESNAAQYS PEALLSIQNH IRKQEAPAPE LDGQQAEEDP GVRDLE ALI DTIQKQLKDR PCRDNIREAF QIYDKEASGY VDRETFFKIC GSYQLPVDDS LIKELIRMCS HGEDKIDYYN FVRAFSN

UniProtKB: EF-hand domain-containing protein 1

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分子 #20: EFHC2

分子名称: EFHC2 / タイプ: protein_or_peptide / ID: 20 / コピー数: 4 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 85.566766 KDa
配列文字列: MGKEKFHKSQ HWGFCNNVRM LVGEDKPGIG GELLFGQKIK PKYSVFPKGM GTDSPSWVAF DKQVLSFDAY LEDEVPDKSQ ENYRIRRYK IYFYLEDDTV EVNEPVLQNS GLPQGIFIRR HRISLPPPNE DQFYTVHHFN VNTDIVFYGR TFKVYDCDAF T KNFLTKIG ...文字列:
MGKEKFHKSQ HWGFCNNVRM LVGEDKPGIG GELLFGQKIK PKYSVFPKGM GTDSPSWVAF DKQVLSFDAY LEDEVPDKSQ ENYRIRRYK IYFYLEDDTV EVNEPVLQNS GLPQGIFIRR HRISLPPPNE DQFYTVHHFN VNTDIVFYGR TFKVYDCDAF T KNFLTKIG VKLNPPGQCP EDPYMKTRRE KLDCMEPICP YESFDTLKQF LEYDRKVLRF FCVWDDSGSV FGDRRELILH YF LSDDTIE IKEVLPHNSG RDAMSLFLQR RKLPKYGPPG VYQPGQLTDQ TVLNVYGGYS ETRVYGFLLD KYQLGKLDQE FYK DTDLSI GTTINVWGRK VLLCDCDDFT KTYYRTKYGI ENFTSIPCKA PSPPKIERKF PPYTGFGSEE DSLRSCIGLM PTPH QRNFK KFIEFDSYGN ISNTLRFFAK LITHKCADVE RMFVISYFLS DDTISVFEPI ERNSGYTGGM FLKRVRVKKP GQEVF KSEF SEYIKAEELY VGAKVNVNGY LFFLVNADEY TLNYMERNSD KFPLSSIELV IQKLKEEECK SRELKQVFTA ADCMHT KMV DFNTFREIMM NLTVGKLTDQ EVITIARRYR VPEDPCPHRN VLVAQAHEQL KKNAFENFER LIAMCVYEDR EKKKVLP SK DIKRLCKSSR LPLNEDLLGS LLSGFEDSEK QINYESFFCA LNWRVNPVPV LEVASYIKER CEDEWLGMPS PIPVKYIY Y LNLLKDVFGV DE

UniProtKB: EF-hand domain-containing family member C2

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分子 #21: Enkurin, TRPC channel interacting protein

分子名称: Enkurin, TRPC channel interacting protein / タイプ: protein_or_peptide / ID: 21 / コピー数: 4 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 30.215129 KDa
配列文字列: MVAMDPTGPS ESIYNLIPSD WKEPPQPPRY VSIFKATVKD DMQKFKTAMK TMGPAKLEVP SPKDFLKKHS KEKILPPKKK FEWNERRKP PVPLRTDHPV MGIQSEKNFI NTNAADVIMG VAKKPKPIYV DKRTGDKHDL ETSGLVPKYI NKKDYGVTPE Y ICKRNEEV ...文字列:
MVAMDPTGPS ESIYNLIPSD WKEPPQPPRY VSIFKATVKD DMQKFKTAMK TMGPAKLEVP SPKDFLKKHS KEKILPPKKK FEWNERRKP PVPLRTDHPV MGIQSEKNFI NTNAADVIMG VAKKPKPIYV DKRTGDKHDL ETSGLVPKYI NKKDYGVTPE Y ICKRNEEV KKAQEEYDNY IQENLRKAAM KRLSDEEREA VLQGLKKNWE EVHKEFQSLS VFIDSIPKKI RKQKLEEEMK QL EHDIGVL EKHKVIYIAN KK

UniProtKB: Enkurin

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分子 #22: Protein FAM166B

分子名称: Protein FAM166B / タイプ: protein_or_peptide / ID: 22 / コピー数: 6 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 30.551627 KDa
配列文字列: MASTFIPGLN PQNPHYIPGY TGHCPLLRFS MGQTYGQMTG QLLRGSPGLA WPPAHRTLLP PIQPPRSPEP RRRSLPVRPG HERLSSSMV PGYTGFVPQA QFIFAKNCSQ VWAEALNGFT QRNGGQGSQE LPKEAKGEKD VEKDQEPKPE VEKEPELGQE A EQASPYSM ...文字列:
MASTFIPGLN PQNPHYIPGY TGHCPLLRFS MGQTYGQMTG QLLRGSPGLA WPPAHRTLLP PIQPPRSPEP RRRSLPVRPG HERLSSSMV PGYTGFVPQA QFIFAKNCSQ VWAEALNGFT QRNGGQGSQE LPKEAKGEKD VEKDQEPKPE VEKEPELGQE A EQASPYSM DDRDPRKFFM SGFTGYVPRA RFLFGSSFPV LSNQALQEFG EMKSPGRSQK DPKHLPALSR TYPQHLGLLP KY GGYVPGY KFQFGRTYGH LTQDALGLST LQKQLLV

UniProtKB: Ciliary microtubule inner protein 2B

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分子 #23: Cilia- and flagella-associated protein 144

分子名称: Cilia- and flagella-associated protein 144 / タイプ: protein_or_peptide / ID: 23 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 16.178324 KDa
配列文字列:
MAGHQKEKAI ADEVHQNQIL RELYLKELRT QKLYTQYHVN PLRKVHTIAR KPMSWHDNLE EPADARFLNL IHHAAQGPRK KYPETQTEG QEIGWDSEPL VNPQRDDRRL NHFRVYKDIT LYKAKMWSLG EDDRHK

UniProtKB: Cilia- and flagella-associated protein 144

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分子 #24: Meiosis-specific nuclear structural protein 1

分子名称: Meiosis-specific nuclear structural protein 1 / タイプ: protein_or_peptide / ID: 24 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 60.538367 KDa
配列文字列: MASIRRTLSF SERHQKLVDI NYCKKLHVEA LQRLQNQTRD QMVQNENDDR AERKRFLRLL QDEQFELDME EAIQKAEENK RLRELQLAQ EEKLATELAK LKRESLKDEK LRQQVRENSA ELRELEKKLK AAYMNKERAA QIAEKDAIKY GQMKRDAEIA R TMMEEHER ...文字列:
MASIRRTLSF SERHQKLVDI NYCKKLHVEA LQRLQNQTRD QMVQNENDDR AERKRFLRLL QDEQFELDME EAIQKAEENK RLRELQLAQ EEKLATELAK LKRESLKDEK LRQQVRENSA ELRELEKKLK AAYMNKERAA QIAEKDAIKY GQMKRDAEIA R TMMEEHER LIKEESAAED KRNQAKAQYS HDLEKQLEEQ GKKKQEAYEQ LLKEKLMIDE IVRKIYEEDQ LERQQRLEKM NT TRRYIEE FQKEQALWRK KKREEMEEEN RKIIEFAKLQ QQREEDRMAK VQEKVKKKRL QLKNMLTQRL EEMLRQREDL EQV RQELYQ EEQAEIYKKK LEEEAEEKLR KQKELKQDFM DQMALKELIL QAAKEEEETF RKAMLAKFAE DDRIELMNAQ KPRM KQLEH KRAVEKLIEE RRNQFLADKQ RELEEWQWQQ RRQGCINAIV EEERLKLLKE HATKLLGYLP KGVFKNEDDI DMLGE EFRK AYQKRSEICE K

UniProtKB: Meiosis-specific nuclear structural protein 1

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分子 #25: Nucleoside diphosphate kinase 7

分子名称: Nucleoside diphosphate kinase 7 / タイプ: protein_or_peptide / ID: 25 / コピー数: 2 / 光学異性体: LEVO / EC番号: nucleoside-diphosphate kinase
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 42.650895 KDa
配列文字列: MNHSERFVFI AEWFDPNASL FRRYELLFYP GDGSVEMHDV KNHRTFLKRT KYEDLHLEDL FIGNKVNIFS RQLVLLDYGD QYTARQLGS KKEKTLALIK PDAVSKAGEI IEIINKAGFT LTKLKMMTLS RKEATDFHID HQSRPFLNEL IQFITSGPII A MEILRDDA ...文字列:
MNHSERFVFI AEWFDPNASL FRRYELLFYP GDGSVEMHDV KNHRTFLKRT KYEDLHLEDL FIGNKVNIFS RQLVLLDYGD QYTARQLGS KKEKTLALIK PDAVSKAGEI IEIINKAGFT LTKLKMMTLS RKEATDFHID HQSRPFLNEL IQFITSGPII A MEILRDDA VCEWKRLLGP ANSGLARTDA PESIRALFGT DGIKNAAHGP DSFACAAREM ELFFPSSGVC GPANTAKFTN CT TCCIVKP HAVSEGLLGK ILMTIRDAGF EISAMQMFNM DRINVEEFYE VYKGVVSEYN EMVTEMYSGP CVAMEIQQTN PTM TFREFC GPADPEIARH LRPGTLRAIF GKTKIQNAVH CTDLPEDGLL EVQYFFKILD N

UniProtKB: Nucleoside diphosphate kinase homolog 7

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分子 #26: Outer dynein arm-docking complex subunit 3

分子名称: Outer dynein arm-docking complex subunit 3 / タイプ: protein_or_peptide / ID: 26 / コピー数: 3 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 72.163984 KDa
配列文字列: MTSPLCWAAA SNAMPSQDQI STPSKVKATQ VQLKPYRSRG KGLVPVWHSL HSKAGPLHAS EGKSAVNMQV AELQRKIQLL EGDRKAFYE STQWNIKKNQ ETINQLREET RVLQLQLTAL LQGDEKVVQA VIREWKSEKP YLKNRTGQQA LEHLDYRLNE K VKQLNALR ...文字列:
MTSPLCWAAA SNAMPSQDQI STPSKVKATQ VQLKPYRSRG KGLVPVWHSL HSKAGPLHAS EGKSAVNMQV AELQRKIQLL EGDRKAFYE STQWNIKKNQ ETINQLREET RVLQLQLTAL LQGDEKVVQA VIREWKSEKP YLKNRTGQQA LEHLDYRLNE K VKQLNALR HQLGLRQKWL EELQLQHSLR ELEIAEAQDS NTEVAKTMRN LENRLEKARM KAEEAEHITS VYLQLKAYLQ EE SLHLGNR LDFMEAEVVR TKHELEELHL VNQEALNARD IAKNQLQYLE ETVFRERKKR ERYLTECKKR AEEKKLQNER MER KTQREH VLLQSDDTLQ DSMYSKEEEL KRRWSMYQME VLFGKVKDAT GVAETHAVVR RFLAQGDTFT QLEMLKSENE QTLL RLKQE KQRLQQELED LKYSGEALLV SEQKRQAELQ GRLKMEEQRR ADAQNQLDRT MRALQITKEG LEHLAGKLNH IVVAG PTYE EGSPGASLDT KGSATPQPQE TGRSVGKMDP KVDDYLPNLL GLVEEKLLKL HSQLENHNVP EMLRHIVDLE FYATLE GKL PSYNTRIALP VAGHKDKFFD EEESEEDDSD VVTRAALKMR SQKLIESRSK RRGRSRRS

UniProtKB: Outer dynein arm-docking complex subunit 3

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分子 #27: PACRG protein

分子名称: PACRG protein / タイプ: protein_or_peptide / ID: 27 / コピー数: 6 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 29.323059 KDa
配列文字列: MVAEKETLSL NKCPAKLPTR TKLLAQQPLP VHQPHSLVSE GFTVKAMMKN SVVRGPPSAG AFKERPTKPT AFRKFYERGD FPIALEHDS KGNKIAWKVE IEKLDYHHYL PLFFDGLCEM TFPYEFFARQ GIHDMLEHGG NKILPVIPQL IIPIKNALNL R NRQVICVT ...文字列:
MVAEKETLSL NKCPAKLPTR TKLLAQQPLP VHQPHSLVSE GFTVKAMMKN SVVRGPPSAG AFKERPTKPT AFRKFYERGD FPIALEHDS KGNKIAWKVE IEKLDYHHYL PLFFDGLCEM TFPYEFFARQ GIHDMLEHGG NKILPVIPQL IIPIKNALNL R NRQVICVT LKVLQHLVVS AEMVGEALVP YYRQILPILN IFKNKNVNSG DGIDYSQQKR ENIGDLIQET LEAFERYGGE DA FINIKYM VPTYESCLLN

UniProtKB: Parkin coregulated gene protein

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分子 #28: Pierce1

分子名称: Pierce1 / タイプ: protein_or_peptide / ID: 28 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 15.673458 KDa
配列文字列:
MSEEDPKACA EPEEPKAGPP PEKTSDWYRV SEDLPARFNN PAWFRGYRTK EPPSVYRTSN QAYGSRAPTV HEMPKVFYPN SYKFSRQVA VGGMFQNNTL NVYMEKSIVT GPDNYITSYD RLNFHPSYRV CRPSICD

UniProtKB: Piercer of microtubule wall 1 protein

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分子 #29: Pierce2

分子名称: Pierce2 / タイプ: protein_or_peptide / ID: 29 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 13.784531 KDa
配列文字列:
MTECDWEKKS TSASNSDTEM KPELPPCVNP GNPVFSCMLD PKTLHTTTSL SKPKMIMYKT NSSNYGEFLP MPQFFPCYYT PREQVFSSH IRATGFYQNN TLNTAPDRTR TLDFPNFQHT L

UniProtKB: Piercer of microtubule wall 2 protein

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分子 #30: RIB43A-like with coiled-coils protein 2

分子名称: RIB43A-like with coiled-coils protein 2 / タイプ: protein_or_peptide / ID: 30 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 44.773418 KDa
配列文字列: MEVAQPKDLK EDFVLAKRRH AELVRQKRIF NARNRIIGGD TTAWDAQVCD QNIKAATEKA RDEAFAAEMR QNDKIACLSE NRERRDRKN LCKAINDFQQ SFQRPETRRE FDLSDPLALK KDRPARQSDY DARNTISGMQ KFMGEDLNFH LRKKFQEEQN R EWSLQQQK ...文字列:
MEVAQPKDLK EDFVLAKRRH AELVRQKRIF NARNRIIGGD TTAWDAQVCD QNIKAATEKA RDEAFAAEMR QNDKIACLSE NRERRDRKN LCKAINDFQQ SFQRPETRRE FDLSDPLALK KDRPARQSDY DARNTISGMQ KFMGEDLNFH LRKKFQEEQN R EWSLQQQK EQMIGRENQK CAEDLYLKTR LQFDETAKHL QNLETATRKA VCATVKEFNK NQALESAEKK IQERKQEQED NL AEISNML RGDLLSENPQ QAASSFGPHR VVPDRWKGMS QEQLEEIRLV QRQQVQEKLR LQEEERQRDM DWDRRRIQKA RAT LLFEQQ QQRLQRGLRR ALDCSNLSLA REQLLQKKHM KELCTNHATE DYFTQFNTGS R

UniProtKB: RIB43A-like with coiled-coils protein 2

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分子 #31: Sperm acrosome associated 9

分子名称: Sperm acrosome associated 9 / タイプ: protein_or_peptide / ID: 31 / コピー数: 7 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 19.345191 KDa
配列文字列:
MMNEVKESLR SVEQKYKIFQ QQQFTFIGAL EHCRENAHDK IRPISSIGQV QSYMEHHCSN STDRRILLMF LDICSELSKL CQHFEALHA GTPVTNNLLE KCKTLVSQSN DLSSLRAKYP HDVVNHLSCD EARNHYGGVV SLIPIILDLM KEWVAHSEKL P RKALQQGA T

UniProtKB: Sperm acrosome associated 9

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分子 #32: Tektin-1

分子名称: Tektin-1 / タイプ: protein_or_peptide / ID: 32 / コピー数: 4 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 48.798375 KDa
配列文字列: MAKLLQQPPK FLRAEWQIAN KNQYHRAEAQ RSRSERLVAE SQRLVDEIEK TTRKSQSDVN KKLEQRLEEV RFWKKELDDK LEQLVYATE DLLLYQTRLQ KALESFKEPL HITEKCLEYR EKRVGIDLVH DEVEQELIKE HEIIRGVMTL LTRTLEETCE Q IRLNRSAK ...文字列:
MAKLLQQPPK FLRAEWQIAN KNQYHRAEAQ RSRSERLVAE SQRLVDEIEK TTRKSQSDVN KKLEQRLEEV RFWKKELDDK LEQLVYATE DLLLYQTRLQ KALESFKEPL HITEKCLEYR EKRVGIDLVH DEVEQELIKE HEIIRGVMTL LTRTLEETCE Q IRLNRSAK YNLEKDLRDK FTAITIDDIC FSLNNNSPNI KYSENVVRVE PNSVSLEDWL DFSNTNVEKA DKQRNNSLTL KA LVDRILF QTASDLRRQC DVVDTAFKNG LKETKDARDK LALHLDKVME EIASQEKNIV VLEKAILDQE GPAKVAHTRL ETR THRPNV ELCRDVAQYR LIKEVDEITH NVARLKETLA QAHVELKGLN RRQLALQEEI QIKENTIYID EVLCVPMRKS IPPR DGDDH GEWAGGSHPE AVC

UniProtKB: Tektin-1

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分子 #33: Tektin-2

分子名称: Tektin-2 / タイプ: protein_or_peptide / ID: 33 / コピー数: 8 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 49.962656 KDa
配列文字列: MATLSVKPSP RFRLPDWQTN SYLLSTNAER QRDASHQIRQ EARVLRNETN NQTIWDEHDN RTRLAERIDT VSRWKEMLDK CLTDLDAEI DALAQMKESA EQNLQAKNLP LDVAIECLTL RESRRDIDVV KDPVEEELHK EVEVIEATKK ALQQKISQAF E KLFLLQEA ...文字列:
MATLSVKPSP RFRLPDWQTN SYLLSTNAER QRDASHQIRQ EARVLRNETN NQTIWDEHDN RTRLAERIDT VSRWKEMLDK CLTDLDAEI DALAQMKESA EQNLQAKNLP LDVAIECLTL RESRRDIDVV KDPVEEELHK EVEVIEATKK ALQQKISQAF E KLFLLQEA RQRLNSDHRG KMETLDIDRG CLSLNLTSPN ISLKINPTRV PNGSTSLQQW DDLSRFNKDH GEAEMKKAIE LR EAIALTI AETNNELEAQ RVATEFAFRK RLREMEKLYS ELKWQEKNTL EEIAELHEDI RHLEEDLRRK LQNLKLCHTR LEA RTYRPN VELCRDQAQY GLTDEVHQLE ATIAALKQKL AQAQDALDAL YKHLARLQAD IACKANSMLL DTKCMDTRRK LTVP AEKFV PEVDTFTRTT NRTLSPLKTC QLELA

UniProtKB: Tektin-2

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分子 #34: Tektin-3

分子名称: Tektin-3 / タイプ: protein_or_peptide / ID: 34 / コピー数: 14 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 56.76091 KDa
配列文字列: MELLGSTLTA TYAHPRPTPT NFLPAISTMA STYRDRFPHY NLTHSLSLPW RPSTYYKAAS NWPTLDPYCT RSQRVSESTM LPFVSNRTT LFTRYTPDDW YRSNLTNFQE SNTSRHNSER LRVDTSRLIQ DKYQQTRKTQ ADSTQNLGER VNDIGFWKSE I IHELDAMI ...文字列:
MELLGSTLTA TYAHPRPTPT NFLPAISTMA STYRDRFPHY NLTHSLSLPW RPSTYYKAAS NWPTLDPYCT RSQRVSESTM LPFVSNRTT LFTRYTPDDW YRSNLTNFQE SNTSRHNSER LRVDTSRLIQ DKYQQTRKTQ ADSTQNLGER VNDIGFWKSE I IHELDAMI GETNELTDIK KRLERALMET EAPLQVAREC LFHREKRMGI DLVHDEVEKE LLTEVDTILC CQERMKLYLD KA IAQLAAN RAAQHELEKD LSDKQSAYRI DDKCHHLRNT SDGVSYFHGV ERVDATVSVP ESWAKFTDDN ILRSQSERAA SAK LRDDIQ NVLVVTANEM WNQFNKVNLA FTNRIAETAD AKNKIQTHLA KTLQEIFQTE MTIESIKKAI VEKSAFLKVA QTRL DERTR RPNIELCRDM AQLRLVNEVY EVDDTIQTLQ QRLRDAEDTL QSLAHTKATL EHDLAVKANS LYIDQDKCMS MRRSF PSTL RLVGFC

UniProtKB: Tektin-3

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分子 #35: Tektin-4

分子名称: Tektin-4 / タイプ: protein_or_peptide / ID: 35 / コピー数: 8 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 52.025488 KDa
配列文字列: MAQTDILLTK EPAPQTVPAC QLPRKLYDVA RNTGAHTSSG LATSGFRTAK YLLDEWFQNC YARYHQAFAD RDQSERQRHE SQQLAAETE ALAQRTQQDS TRKVGERLQD MHGWKSELQR QVEELVSETE LLLAQKQRLE RALDATAGPF SIVTDNLQCR E RRQHPDLV ...文字列:
MAQTDILLTK EPAPQTVPAC QLPRKLYDVA RNTGAHTSSG LATSGFRTAK YLLDEWFQNC YARYHQAFAD RDQSERQRHE SQQLAAETE ALAQRTQQDS TRKVGERLQD MHGWKSELQR QVEELVSETE LLLAQKQRLE RALDATAGPF SIVTDNLQCR E RRQHPDLV RDCVEIELLK EAELIRNIQE LLKRTIKQAV SQIRLNWEHK ETCEMDWSDK VEAYNIDEAC CRYNNQSTDV QF YPHSAKF EESASTPETW AKFTQEHLYR AERERLASVN LRNLIDCILQ DTSEDLRLQC DAVNLAFGRR CEELEDARHK LEH HLRKTL REISDQEHNI AALKQAIKDK EAPLKVAQTR LYQRSHRPNV ELCRDAAQFR LASEVEELNL SLAALKEKLL EAEQ SLRNL EDTRMSLEKD IAIKTNSLFI DRHKCMAHRA HYPTVLQLAG YQ

UniProtKB: Tektin-4

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分子 #36: TTC25 protein

分子名称: TTC25 protein / タイプ: protein_or_peptide / ID: 36 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 78.492633 KDa
配列文字列: MADPENEVLR STFPSYMAEG ERLYLCGEFA KAAHSFSNAL HLQSGDKNCL VARSKCFLKM GELEKSLEDA EASLQGDPTF CKGILQKAE TLYTMGDFEF ALVFYHRGYK LRPDREFKVG IQKAQEAINN SVGSPSSIKL ENKGDLSFLS KQAESMRAQQ K PHPVRQLI ...文字列:
MADPENEVLR STFPSYMAEG ERLYLCGEFA KAAHSFSNAL HLQSGDKNCL VARSKCFLKM GELEKSLEDA EASLQGDPTF CKGILQKAE TLYTMGDFEF ALVFYHRGYK LRPDREFKVG IQKAQEAINN SVGSPSSIKL ENKGDLSFLS KQAESMRAQQ K PHPVRQLI HHPKRESKRK GSLKSEKIVR QLLGELYVDK EYLEKLLLDE DLIKGTIKHG LTVEDLIMTG INYLETRSDF WR QQKPIYA RERDRKLMQE KWLRDRKRRP SQTARYILKS LEDIDMLLTS GSAEGSLQKA EKVLKKVLEW NKEEVPNKDE LVG NLYSCI GNAQIELGQM VAALQSHRKD LEIAKEYDLP DAKSRALDNI GRVFARVGKF QQAIDTWEEK IPLAKTTLEK TWLF HEIGR CYLELDQAWE AQSYGEKSQQ CAEEEGDMEW QLNASVLVAQ AQVKLRDFES AVNNFEKALE RAKLVHNNEA QQAII NALD DANKGIIEEL KKTNYREILK EKKEKENATM LDGQTRTAKE KETRKTKDEP EKVMKQWVQE QTEKQLEGVL SKETLG VTA RQPEQRQRED PEKASWRKEL GAKERGPGDT AKGQFGEAGR TEQNREETRE IYRRPSELDQ NLSDESSPRE SEGLEKR LS KTDGGELEAL GKTESGEIKE MEITENSEKI EKDEKEDEPI E

UniProtKB: Outer dynein arm-docking complex subunit 4

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分子 #37: Ciliary microtubule associated protein 1A

分子名称: Ciliary microtubule associated protein 1A / タイプ: protein_or_peptide / ID: 37 / コピー数: 4 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 27.684936 KDa
配列文字列: MAEEVWVGTW RPHRPRGPIM ALYSSPGPKY LIPPTTGFVK HTPTKLRAPA YSFRGAPMLL AENCSPGPRY SVNPKILRTG KDLGPAYSI LGRYHTKTTL TPGPGDYFPE KSTKHVFDSA PSHSISARTK TFRVDSTPGP AAYMLPMVMG PHTIGKVSQP S FSIKGRSK ...文字列:
MAEEVWVGTW RPHRPRGPIM ALYSSPGPKY LIPPTTGFVK HTPTKLRAPA YSFRGAPMLL AENCSPGPRY SVNPKILRTG KDLGPAYSI LGRYHTKTTL TPGPGDYFPE KSTKHVFDSA PSHSISARTK TFRVDSTPGP AAYMLPMVMG PHTIGKVSQP S FSIKGRSK LGSFSDDLHK TPGPAAYRQT DVQVTKFKAP QYTMAARVEP PGDKTLKPGP GAHSPEKVTM TRPCAPVVSF GI KHSDYMT PLVVDVD

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分子 #38: Ciliary microtubule associated protein 1C

分子名称: Ciliary microtubule associated protein 1C / タイプ: protein_or_peptide / ID: 38 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 30.860854 KDa
配列文字列: MKLPKGVKNP VFYGQQPEKK VPMSSGHEIK QTPVVLAMLK GPGPAKYLRP SCTGYIDHDV SMFQEPAYTL HAWHPEKRIM DIRSPGPCY FLDPKITRFG MVSCPQVPMA EHISNLRLSP TPAPCHYHLE KTHLPGERRA PGYSFGFRCP YRVMDPNPGP N RYQMPLLL ...文字列:
MKLPKGVKNP VFYGQQPEKK VPMSSGHEIK QTPVVLAMLK GPGPAKYLRP SCTGYIDHDV SMFQEPAYTL HAWHPEKRIM DIRSPGPCY FLDPKITRFG MVSCPQVPMA EHISNLRLSP TPAPCHYHLE KTHLPGERRA PGYSFGFRCP YRVMDPNPGP N RYQMPLLL GPNLPANKAA PCYSLAPLDK NWFYKNMSRG PGPAAHTRPE PSVYQNRSPV YSMAKRFGYP VDHTPRPGPG SH NVQQVRA HKPRPPAFTM GIKHSPHLCP LIVDIRD

UniProtKB: Ciliary microtubule associated protein 1C

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分子 #39: Cilia and flagella associated protein 90

分子名称: Cilia and flagella associated protein 90 / タイプ: protein_or_peptide / ID: 39 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 16.820848 KDa
配列文字列:
MEDDEEEITA AALRGKPRPL PISALSAFSY IPPRRQDPKE HSYYYRQGWT GIISLYDCVF KRDPGYNQKL HRDDREHAKS LGLRINEEE CERPVGVLSS SVYGRRIDQP VEPLNRDHGR AGHVKADFYR KNDITSIKAP GFGHISPA

UniProtKB: Cilia and flagella associated protein 90

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分子 #40: Sperm associated antigen 8

分子名称: Sperm associated antigen 8 / タイプ: protein_or_peptide / ID: 40 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 51.604398 KDa
配列文字列: METSESTDRS QSRCLDLQPS SDGLGSSSDP FSSWDGRHRS ALVAATAAAS AAATAASTAR AAALWTKSPA PYSHGNLLTE PSSDSLTER YTGPRFTHKI SHGRLGFQPA YFSHIAWNPY TTNDLSSSRG PIPGSSSGPV PGSSSSPGPD SSSDPGPSSS S GPGGSPGG ...文字列:
METSESTDRS QSRCLDLQPS SDGLGSSSDP FSSWDGRHRS ALVAATAAAS AAATAASTAR AAALWTKSPA PYSHGNLLTE PSSDSLTER YTGPRFTHKI SHGRLGFQPA YFSHIAWNPY TTNDLSSSRG PIPGSSSGPV PGSSSSPGPD SSSDPGPSSS S GPGGSPGG SGRGPGHGPG PGGGSGQGPG GGSGQGTDLG PAIDSRHSPG HGHGPRFNFS APVGFRNPRG DLIPNYTGCK HH CHWEPQK QSWKFLKVSE PGARGLWKPP EVEGKSTVLS ETLPRGQCLL YNWEEERATN YLDQVPVMQD GSESFFFRHG HRG LLTLQP QSPTSSCTTQ KDSYQPPKSH CQPIRGKREA ILEMLLRQQI CKEVQAEQEP TRKDSEVESV THHDYKKELV QAGP PAPTK IHDYHTEQPE TFWLERAPQL PGVSNIRTLD TPFRKNCSFS TPVPLSLEQP LPFEPESYSQ HGEISSLACQ GGGQG GGGG

UniProtKB: Sperm-associated antigen 8

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分子 #41: Tubulin beta-4B chain

分子名称: Tubulin beta-4B chain / タイプ: protein_or_peptide / ID: 41 / コピー数: 130 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 49.877824 KDa
配列文字列: MREIVHLQAG QCGNQIGAKF WEVISDEHGI DPTGTYHGDS DLQLERINVY YNEATGGKYV PRAVLVDLEP GTMDSVRSGP FGQIFRPDN FVFGQSGAGN NWAKGHYTEG AELVDSVLDV VRKEAESCDC LQGFQLTHSL GGGTGSGMGT LLISKIREEY P DRIMNTFS ...文字列:
MREIVHLQAG QCGNQIGAKF WEVISDEHGI DPTGTYHGDS DLQLERINVY YNEATGGKYV PRAVLVDLEP GTMDSVRSGP FGQIFRPDN FVFGQSGAGN NWAKGHYTEG AELVDSVLDV VRKEAESCDC LQGFQLTHSL GGGTGSGMGT LLISKIREEY P DRIMNTFS VVPSPKVSDT VVEPYNATLS VHQLVENTDE TYCIDNEALY DICFRTLKLT TPTYGDLNHL VSATMSGVTT CL RFPGQLN ADLRKLAVNM VPFPRLHFFM PGFAPLTSRG SQQYRALTVP ELTQQMFDAK NMMAACDPRH GRYLTVAAVF RGR MSMKEV DEQMLNVQNK NSSYFVEWIP NNVKTAVCDI PPRGLKMSAT FIGNSTAIQE LFKRISEQFT AMFRRKAFLH WYTG EGMDE MEFTEAESNM NDLVSEYQQY QDATAEEEGE FEEEAEEEVA

UniProtKB: Tubulin beta-4B chain

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分子 #42: Tubulin alpha-1D chain

分子名称: Tubulin alpha-1D chain / タイプ: protein_or_peptide / ID: 42 / コピー数: 134 / 光学異性体: LEVO
由来(天然)生物種: Bos taurus (ウシ)
分子量理論値: 50.335594 KDa
配列文字列: MRECISVHVG QAGVQIGNAC WELYCLEHGI QPDGQMPSDK TIGGGDDSFN TFFSETGAGK HVPRAVFVDL EPTVIDEVRT GTYRQLFHP EQLITGKEDA ANNYARGHYT IGKELIDLVL DRIRKLADQC TGLQGFLIFH SFGGGTGSGF TSLLMERLSV D YGKKSKLE ...文字列:
MRECISVHVG QAGVQIGNAC WELYCLEHGI QPDGQMPSDK TIGGGDDSFN TFFSETGAGK HVPRAVFVDL EPTVIDEVRT GTYRQLFHP EQLITGKEDA ANNYARGHYT IGKELIDLVL DRIRKLADQC TGLQGFLIFH SFGGGTGSGF TSLLMERLSV D YGKKSKLE FSIYPAPQVS TAVVEPYNSI LTTHTTLEHS DCAFMVDNEA IYDICRRNLD IERPTYTNLN RLIGQIVSSI TA SLRFDGA LNVDLTEFQT NLVPYPRIHF PLATYAPVIS AEKAYHEQLS VAEITNACFE PANQMVKCDP RHGKYMACCL LYR GDVVPK DVNAAIATIK TKRTIQFVDW CPTGFKVGIN YQPPTVVPGG DLAKVQRAVC MLSNTTAIAE AWARLDHKFD LMYA KRAFV HWYVGEGMEE GEFSEAREDM AALEKDYEEV GMDSVEGEGE EEEGDEY

UniProtKB: Tubulin alpha-1D chain

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分子 #43: GUANOSINE-5'-DIPHOSPHATE

分子名称: GUANOSINE-5'-DIPHOSPHATE / タイプ: ligand / ID: 43 / コピー数: 130 / 式: GDP
分子量理論値: 443.201 Da
Chemical component information

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, エネルギー貯蔵分子*YM

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分子 #44: MAGNESIUM ION

分子名称: MAGNESIUM ION / タイプ: ligand / ID: 44 / コピー数: 106 / 式: MG
分子量理論値: 24.305 Da

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分子 #45: GUANOSINE-5'-TRIPHOSPHATE

分子名称: GUANOSINE-5'-TRIPHOSPHATE / タイプ: ligand / ID: 45 / コピー数: 134 / 式: GTP
分子量理論値: 523.18 Da
Chemical component information

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, エネルギー貯蔵分子*YM

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実験情報

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構造解析

手法クライオ電子顕微鏡法
解析単粒子再構成法
試料の集合状態filament

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試料調製

緩衝液pH: 7.4
凍結凍結剤: ETHANE

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電子顕微鏡法

顕微鏡TFS KRIOS
撮影フィルム・検出器のモデル: GATAN K3 BIOQUANTUM (6k x 4k)
平均電子線量: 50.0 e/Å2
電子線加速電圧: 300 kV / 電子線源: FIELD EMISSION GUN
電子光学系照射モード: FLOOD BEAM / 撮影モード: BRIGHT FIELD / 最大 デフォーカス（公称値）: 2.5 µm / 最小 デフォーカス（公称値）: 0.5 µm
実験機器
モデル: Titan Krios / 画像提供: FEI Company

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画像解析

初期モデルモデルのタイプ: EMDB MAP
EMDB ID:

40619

最終 再構成解像度のタイプ: BY AUTHOR / 解像度: 3.52 Å / 解像度の算出法: FSC 0.143 CUT-OFF / 使用した粒子像数: 153589
初期 角度割当タイプ: MAXIMUM LIKELIHOOD
最終 角度割当タイプ: MAXIMUM LIKELIHOOD
FSC曲線 (解像度の算出)

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万見について

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お知らせ

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2022年2月9日: EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

  • EMDBのヘッダファイルのバージョン3が、公式のフォーマットとなりました。
  • これまでは公式だったバージョン1.9は、アーカイブから削除されます。

関連情報:EMDBヘッダ

外部リンク:wwPDBはEMDBデータモデルのバージョン3へ移行します

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2020年8月12日: 新型コロナ情報

新型コロナ情報

URL: https://pdbj.org/emnavi/covid19.php

新ページ: EM Navigatorに新型コロナウイルスの特設ページを開設しました。

関連情報:Covid-19情報 / 2020年3月5日: 新型コロナウイルスの構造データ

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2020年3月5日: 新型コロナウイルスの構造データ

新型コロナウイルスの構造データ

関連情報:万見生物種 / 2020年8月12日: 新型コロナ情報

外部リンク:COVID-19特集ページ - PDBj / 今月の分子2020年2月：コロナウイルスプロテーアーゼ

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2019年1月31日: EMDBのIDの桁数の変更

EMDBのIDの桁数の変更

  • EMDBエントリに付与されているアクセスコード(EMDB-ID)は4桁の数字(例、EMD-1234)でしたが、間もなく枯渇します。これまでの4桁のID番号は4桁のまま変更されませんが、4桁の数字を使い切った後に発行されるIDは5桁以上の数字(例、EMD-12345)になります。5桁のIDは2019年の春頃から発行される見通しです。
  • EM Navigator/万見では、接頭語「EMD-」は省略されています。

関連情報:Q: 「EMD」とは何ですか？ / 万見/EM NavigatorにおけるID/アクセスコードの表記

外部リンク:EMDB Accession Codes are Changing Soon! / PDBjへお問い合わせ

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2017年7月12日: PDB大規模アップデート

PDB大規模アップデート

  • 新バージョンのPDBx/mmCIF辞書形式に基づくデータがリリースされました。
  • 今回の更新はバージョン番号が4から5になる大規模なもので、全エントリデータの書き換えが行われる「Remediation」というアップデートに該当します。
  • このバージョンアップで、電子顕微鏡の実験手法に関する多くの項目の書式が改定されました(例：em_softwareなど)。
  • EM NavigatorとYorodumiでも、この改定に基づいた表示内容になります。

外部リンク:wwPDB Remediation / OneDepデータ基準に準拠した、より強化された内容のモデル構造ファイルが、PDBアーカイブで公開されました。

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万見 (Yorodumi)

幾万の構造データを、幾万の視点から

  • 万見(Yorodumi)は、EMDB/PDB/SASBDBなどの構造データを閲覧するためのページです。
  • EM Navigatorの詳細ページの後継、Omokage検索のフロントエンドも兼ねています。

関連情報:EMDB / PDB / SASBDB / 3つのデータバンクの比較 / 万見検索 / 2016年8月31日: 新しいEM Navigatorと万見 / 万見文献 / Jmol/JSmol / 機能・相同性情報 / 新しいEM Navigatorと万見の変更点

他の情報も見る