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- SASDDL8: Integrin beta4, fragment of the cytoplasmic region that includes ... -
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Open data
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Basic information
Entry | Database: SASBDB / ID: SASDDL8 |
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![]() | Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant R1475A
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Function / homology | Isoform Beta-4A of Integrin beta-4![]() |
Biological species | ![]() |
![]() | ![]() Title: Integrin α6β4 recognition of a linear motif of bullous pemphigoid antigen BP230 controls its recruitment to hemidesmosomes: Supplemental figures S1 to S10 and table S1 Authors: Manso J / Gómez-Hernández M / Carabias A / Alonso-García N / García-Rubio I / Kreft M / Sonnenberg A |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
-Models
Model #2066 | ![]() Type: dummy / Software: (r9988) / Radius of dummy atoms: 1.50 A / Chi-square value: 0.979 / P-value: 0.420599 ![]() |
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Sample
![]() | Name: Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant R1475A Specimen concentration: 1.30-10.50 |
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Buffer | Name: 20 mM Sodium Phosphate 150 mM NaCl 5% glycerol 3 mM DTT Concentration: 20.00 mM / pH: 7.5 / Composition: 150 mM NaCl, 5% glycerol, 3 mM DTT |
Entity #1105 | Name: B4 CS-FnIII-3,4 / Type: protein / Description: Integrin beta-4 (1436-1666) R1475A / Formula weight: 25.52 / Num. of mol.: 1 / Source: Homo sapiens / References: UniProt: P16144-2 Sequence: GSHMLPRDYS TLTSVSSHDS RLTAGVPDTP TRLVFSALGP TSLAVSWQEP RCERPLQGYS VEYQLLNGGE LHRLNIPNPA QTSVVVEDLL PNHSYVFRVR AQSQEGWGRE REGVITIESQ VHPQSPLCPL PGSAFTLSTP SAPGPLVFTA LSPDSLQLSW ERPRRPNGDI ...Sequence: GSHMLPRDYS TLTSVSSHDS RLTAGVPDTP TRLVFSALGP TSLAVSWQEP RCERPLQGYS VEYQLLNGGE LHRLNIPNPA QTSVVVEDLL PNHSYVFRVR AQSQEGWGRE REGVITIESQ VHPQSPLCPL PGSAFTLSTP SAPGPLVFTA LSPDSLQLSW ERPRRPNGDI VGYLVTCEMA QGGGPATAFR VDGDSPESRL TVPGLSENVP YKFKVQARTT EGFGPEREGI ITIES |
-Experimental information
Beam | Instrument name: PETRA III EMBL P12 / City: Hamburg / 国: Germany ![]() | ||||||||||||||||||||||||||||||
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Detector | Name: Pilatus 2M | ||||||||||||||||||||||||||||||
Scan | Measurement date: Nov 26, 2013 / Cell temperature: 10 °C / Exposure time: 0.05 sec. / Number of frames: 30 / Unit: 1/nm /
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Distance distribution function P(R) |
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Result | Comments: 'Synchrotron SAXS data from solutions of a fragment of the cytoplasmic region of the human integrin Beta4 subunit. This fragment includes the final part of a region named the
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