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Open data
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Basic information
Entry | Database: SASBDB / ID: SASDBA9 |
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![]() | E. coli CcdB2-CcdA2-CcdB2 toxin/antitoxin heterohexamer complex
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Function / homology | ![]() DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity / toxin sequestering activity / negative regulation of DNA-templated DNA replication / protein-containing complex disassembly / toxin-antitoxin complex / plasmid maintenance / transcription repressor complex / negative regulation of DNA-templated transcription / DNA binding Similarity search - Function |
Biological species | ![]() ![]() |
![]() | ![]() Title: Molecular mechanism governing ratio-dependent transcription regulation in the ccdAB operon Authors: Vandervelde A / Drobnak I / Hadži S / Sterckx Y / Welte T / De Greve H / Charlier D / Efremov R / Loris R |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
-Models
Model #908 | ![]() Type: atomic / Software: Crysol / Radius of dummy atoms: 1.90 A / Chi-square value: 2.480 ![]() |
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Sample
![]() | Name: E. coli CcdB2-CcdA2-CcdB2 toxin/antitoxin heterohexamer complex Entity id: 507 / 508 / 509 |
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Buffer | Name: 10 mM Tris 50 mM NaCl / pH: 7.3 |
Entity #507 | Type: protein / Description: Toxin CcdB / Formula weight: 11.706 / Num. of mol.: 2 / Source: Escherichia coli (strain K12) / References: UniProt: P62554 Sequence: MQFKVYTYKR ESRYRLFVDV QSDIIDTPGR RMVIPLASAR LLSDKVSREL YPVVHIGDES WRMMTTDMAS VPVSVIGEEV ADLSHRENDI KNAINLMFWG I |
Entity #508 | Type: protein / Description: Antitoxin CcdA / Formula weight: 8.372 / Num. of mol.: 2 / Source: Escherichia coli (strain K12) / References: UniProt: P62552 Sequence: MKQRITVTVD SDSYQLLKAY DVNISGLVST TMQNEARRLR AERWKAENQE GMAEVARFIE MNGSFADENR DW |
Entity #509 | Type: protein / Description: Toxin CcdB / Formula weight: 11.706 / Num. of mol.: 2 / Source: Escherichia coli (strain K12) / References: UniProt: P62554 Sequence: MQFKVYTYKR ESRYRLFVDV QSDIIDTPGR RMVIPLASAR LLSDKVSREL YPVVHIGDES WRMMTTDMAS VPVSVIGEEV ADLSHRENDI KNAINLMFWG I |
-Experimental information
Beam | Instrument name: SOLEIL SWING ![]() ![]() | ||||||||||||||||||||||||||||||||||||
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Detector | Name: AVIEX / Type: CCD | ||||||||||||||||||||||||||||||||||||
Scan |
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Distance distribution function P(R) |
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Result |
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