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基本情報
登録情報 | データベース: PDB / ID: 8gym | ||||||
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タイトル | Cryo-EM structure of Tetrahymena thermophila respiratory mega-complex MC IV2+(I+III2+II)2 | ||||||
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![]() | ELECTRON TRANSPORT / Electron transport chain / supercomplex / membrane protein / Tetrahymena thermophila | ||||||
機能・相同性 | ![]() NADH:ubiquinone reductase (H+-translocating) / thiosulfate transmembrane transporter activity / oxaloacetate transmembrane transporter activity / lipid-A-disaccharide synthase / lipid-A-disaccharide synthase activity / malate transmembrane transporter activity / quinol-cytochrome-c reductase / protein maturation by [2Fe-2S] cluster transfer / medium-chain fatty acid-CoA ligase activity / succinate transmembrane transporter activity ...NADH:ubiquinone reductase (H+-translocating) / thiosulfate transmembrane transporter activity / oxaloacetate transmembrane transporter activity / lipid-A-disaccharide synthase / lipid-A-disaccharide synthase activity / malate transmembrane transporter activity / quinol-cytochrome-c reductase / protein maturation by [2Fe-2S] cluster transfer / medium-chain fatty acid-CoA ligase activity / succinate transmembrane transporter activity / P450-containing electron transport chain / : / sulfate transmembrane transporter activity / mitochondrial electron transport, succinate to ubiquinone / mitochondrial cytochrome c oxidase assembly / succinate dehydrogenase / protein processing involved in protein targeting to mitochondrion / succinate dehydrogenase (quinone) activity / phosphate ion transmembrane transport / : / : / cytochrome-c oxidase / antiporter activity / ubiquinone-6 biosynthetic process / ubiquinol-cytochrome-c reductase activity / oxidoreductase activity, acting on NAD(P)H / mitochondrial electron transport, cytochrome c to oxygen / anaerobic respiration / cytochrome-c oxidase activity / 3 iron, 4 sulfur cluster binding / lipid A biosynthetic process / mitochondrial electron transport, ubiquinol to cytochrome c / NADH:ubiquinone reductase (H+-translocating) / Golgi organization / NADH dehydrogenase activity / : / mitochondrial electron transport, NADH to ubiquinone / transmembrane transporter activity / : / endoplasmic reticulum-Golgi intermediate compartment / chloroplast thylakoid membrane / ubiquinone binding / mitochondrial respiratory chain complex I assembly / acyl binding / NADH dehydrogenase (ubiquinone) activity / acyl carrier activity / quinone binding / electron transport coupled proton transport / ATP synthesis coupled electron transport / tricarboxylic acid cycle / aerobic respiration / respiratory electron transport chain / mitochondrion organization / fatty acid metabolic process / chloroplast / mitochondrial membrane / electron transport chain / phospholipid binding / metalloendopeptidase activity / 2 iron, 2 sulfur cluster binding / NAD binding / protein transport / FMN binding / flavin adenine dinucleotide binding / 4 iron, 4 sulfur cluster binding / response to oxidative stress / mitochondrial inner membrane / membrane => GO:0016020 / oxidoreductase activity / electron transfer activity / ribosome / copper ion binding / DNA-binding transcription factor activity / heme binding / protein-containing complex binding / negative regulation of apoptotic process / protein kinase binding / endoplasmic reticulum / mitochondrion / membrane / nucleus / metal ion binding / plasma membrane / cytosol 類似検索 - 分子機能 Surfeit locus 1/Shy1 / Surfeit locus 1/4 / TraB/PryY-like / SURF1 family / SURF1 family profile. / CTF transcription factor/nuclear factor 1, DNA-binding domain / CTF/NF-I DNA-binding domain profile. / Glycosyl transferase, family 19 / Lipid-A-disaccharide synthetase / Tim10-like ...Surfeit locus 1/Shy1 / Surfeit locus 1/4 / TraB/PryY-like / SURF1 family / SURF1 family profile. / CTF transcription factor/nuclear factor 1, DNA-binding domain / CTF/NF-I DNA-binding domain profile. / Glycosyl transferase, family 19 / Lipid-A-disaccharide synthetase / Tim10-like / Tim10-like domain superfamily / Tim10/DDP family zinc finger / Mitochondrial substrate/solute carrier / Mitochondrial carrier domain superfamily / : / Mitochondrial carrier protein / Solute carrier (Solcar) repeat profile. / Iron-binding zinc finger, CDGSH type / MitoNEET, CDGSH iron-sulfur domain / CDGSH-type zinc finger. Function unknown. / Dynactin subunit 5 / NADH-ubiquinone oxidoreductase, 21kDa subunit, N-terminal / NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit / Succinate dehydrogenase, flavoprotein subunit / Adrenodoxin / Succinate dehydrogenase/fumarate reductase, flavoprotein subunit / Fumarate reductase/succinate dehydrogenase, FAD-binding site / FAD-dependent oxidoreductase SdhA/FrdA/AprA / Fumarate reductase / succinate dehydrogenase FAD-binding site. / 4Fe-4S dicluster domain / Succinate dehydrogenase/fumarate reductase iron-sulphur protein / Succinate dehydogenase/fumarate reductase N-terminal / 2Fe-2S iron-sulfur cluster binding domain / Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal / Fumarate reductase flavoprotein C-term / Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily / Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily / FAD-dependent oxidoreductase 2, FAD binding domain / Alpha-helical ferredoxin / Cytochrome c oxidase subunit Vb, zinc binding region signature. / FAD binding domain / Cytochrome c oxidase, subunit Vb / Cytochrome c oxidase, subunit Vb superfamily / Cytochrome c oxidase subunit Vb / Cytochrome c oxidase subunit Vb, zinc binding domain profile. / DnaJ domain / Ubiquinol-cytochrome C reductase hinge domain / Ubiquinol-cytochrome C reductase hinge domain superfamily / Ubiquinol-cytochrome C reductase hinge protein / Cytochrome c/quinol oxidase subunit II / DnaJ molecular chaperone homology domain / dnaJ domain profile. / Cytochrome c1 / Cytochrome C1 family / 2Fe-2S ferredoxin, iron-sulphur binding site / 2Fe-2S ferredoxin-type iron-sulfur binding region signature. / Chaperone J-domain superfamily / Cytochrome b/b6, C-terminal domain superfamily / Cytochrome b/b6/petB / DnaJ domain / Cytochrome c oxidase, subunit I, copper-binding site / Heme-copper oxidase catalytic subunit, copper B binding region signature. / Cytochrome c oxidase-like, subunit I domain / Cytochrome oxidase subunit I profile. / Cytochrome c oxidase subunit I / Hexapeptide repeat / Cytochrome c oxidase-like, subunit I superfamily / Cytochrome C and Quinol oxidase polypeptide I / Rieske iron-sulphur protein, C-terminal / Cytochrome b/b6, N-terminal / Cytochrome b/b6-like domain superfamily / Cytochrome b/b6 N-terminal region profile. / Di-haem cytochrome, transmembrane / Cytochrome C oxidase subunit II, periplasmic domain / 2Fe-2S iron-sulfur cluster binding domain / Cytochrome c oxidase subunit II-like C-terminal / Cytochrome oxidase subunit II copper A binding domain profile. / Soluble ligand binding domain / Rieske iron-sulphur protein / SLBB domain / Bacterial transferase hexapeptide (six repeats) / Zinc finger, CHCC-type / Zinc-finger domain / Peptidase M16, C-terminal / Peptidase M16 inactive domain / Peptidase M16, N-terminal / Insulinase (Peptidase family M16) / Metalloenzyme, LuxS/M16 peptidase-like / NADH dehydrogenase ubiquinone Fe-S protein 4-like superfamily / NADH dehydrogenase ubiquinone Fe-S protein 4 / NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2 / NADH dehydrogenase ubiquinone Fe-S protein 4, mitochondrial / NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 / NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 / ETC complex I subunit conserved region / NADH ubiquinone oxidoreductase subunit NDUFA12 / NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6 / Thioredoxin / NADH-quinone oxidoreductase, chain G, C-terminal / NADH-ubiquinone oxidoreductase subunit G, C-terminal 類似検索 - ドメイン・相同性 1,2-Distearoyl-sn-glycerophosphoethanolamine / ADENOSINE-5'-DIPHOSPHATE / CARDIOLIPIN / COPPER (II) ION / FE3-S4 CLUSTER / FLAVIN-ADENINE DINUCLEOTIDE / FE2/S2 (INORGANIC) CLUSTER / FLAVIN MONONUCLEOTIDE / HEME-A / HEME C ...1,2-Distearoyl-sn-glycerophosphoethanolamine / ADENOSINE-5'-DIPHOSPHATE / CARDIOLIPIN / COPPER (II) ION / FE3-S4 CLUSTER / FLAVIN-ADENINE DINUCLEOTIDE / FE2/S2 (INORGANIC) CLUSTER / FLAVIN MONONUCLEOTIDE / HEME-A / HEME C / PROTOPORPHYRIN IX CONTAINING FE / Chem-NDP / Chem-P5S / 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE / 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE / IRON/SULFUR CLUSTER / Phosphatidylinositol / UBIQUINONE-10 / Chem-ZMP / Transmembrane protein, putative / NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 / Oxoglutarate/malate translocator protein, putative / NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit / Transmembrane protein, putative / Transmembrane protein / SURF1-like protein / Uncharacterized protein / Uncharacterized protein / Diphthamide synthesis protein / Transmembrane protein / Transmembrane protein, putative / Uncharacterized protein / SURF1-like protein / Transmembrane protein / NADH dehydrogenase, putative / Transmembrane protein / succinate dehydrogenase / Transmembrane protein, putative / Gamma-carbonic anhydrase / Transmembrane protein / Iron-binding zinc finger CDGSH type protein / Transcription factor apfi protein, putative / Uncharacterized protein / Transmembrane protein, putative / Uncharacterized protein / Ribosomal protein L51/S25/CI-B8 domain protein / Transmembrane protein / Acyl carrier protein / Transmembrane protein / NADH-ubiquinone oxidoreductase 1, chain, putative / NADH-ubiquinone oxidoreductase 24 kDa subunit / Uncharacterized protein / Transmembrane protein, putative / Transmembrane protein / Transmembrane protein / Transmembrane protein, putative / Peptidase M16 inactive domain protein / Transmembrane protein, putative / Rieske iron-sulfur protein, ubiquinol-cytochrome C reductase iron-sulfur subunit / Transmembrane protein / Uncharacterized protein / Transmembrane protein, putative / Uncharacterized protein / M16 family peptidase, putative / Zinc-finger protein / NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial / Transmembrane protein / NAD-dependent epimerase/dehydratase family protein / Transmembrane protein, putative / Transmembrane protein / NADH dehydrogenase subunit 1 / Uncharacterized protein / Thioredoxin / Ubiquinol-cytochrome C reductase hinge protein / CTF/NF-I domain-containing protein / Transmembrane protein, putative / Transmembrane protein, putative / DnaJ domain protein / lipid-A-disaccharide synthase / Transmembrane protein / Protein phosphatase 2C, putative / Transmembrane protein, putative / Transmembrane protein, putative / Uncharacterized protein / Transmembrane protein, putative / Transmembrane protein / Transmembrane protein, putative / 2 iron, 2 sulfur cluster-binding protein / Transmembrane protein, putative / Transmembrane protein / Acyl carrier protein / Gamma-carbonic anhydrase / Uncharacterized protein / Transmembrane protein, putative / Carrier protein / Uncharacterized protein / Tim10/DDP family zinc finger protein / Transmembrane protein / Uncharacterized protein / Uncharacterized protein 類似検索 - 構成要素 | ||||||
生物種 | ![]() | ||||||
手法 | 電子顕微鏡法 / 単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 2.96 Å | ||||||
![]() | Wu, M.C. / Hu, Y.Q. / Han, F.Z. / Zhou, L. | ||||||
資金援助 | ![]()
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![]() | ![]() タイトル: Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae. 著者: Fangzhu Han / Yiqi Hu / Mengchen Wu / Zhaoxiang He / Hongtao Tian / Long Zhou / ![]() 要旨: Tetrahymena thermophila, a classic ciliate model organism, has been shown to possess tubular mitochondrial cristae and highly divergent electron transport chain involving four transmembrane protein ...Tetrahymena thermophila, a classic ciliate model organism, has been shown to possess tubular mitochondrial cristae and highly divergent electron transport chain involving four transmembrane protein complexes (I-IV). Here we report cryo-EM structures of its ~8 MDa megacomplex IV+ (I + III+ II), as well as a ~ 10.6 MDa megacomplex (IV + I + III+ II) at lower resolution. In megacomplex IV+ (I + III+ II), each CIV protomer associates one copy of supercomplex I + III and one copy of CII, forming a half ring-shaped architecture that adapts to the membrane curvature of mitochondrial cristae. Megacomplex (IV+ I + III+ II) defines the relative position between neighbouring half rings and maintains the proximity between CIV and CIII cytochrome c binding sites. Our findings expand the current understanding of divergence in eukaryotic electron transport chain organization and how it is related to mitochondrial morphology. | ||||||
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集合体
登録構造単位 | 1t: Tim10/DDP family zinc finger protein 2e: NmrA domain-containing protein 2f: Transmembrane protein, putative 2g: SDHTT3 2h: Diphthamide synthesis protein 2i: DUF4885 domain-containing protein 2j: Transmembrane protein, putative 2k: Transmembrane protein, putative 2l: Transposase 2m: Transmembrane protein, putative 2n: Transmembrane protein, putative 2o: SDHTT11 2t: Zf-Tim10_DDP domain-containing protein 3t: Zf-Tim10_DDP domain-containing protein 4a: Phage protein 4t: Transposase 5t: Cullin domain-containing protein 6a: Transmembrane protein, putative 6b: Structural protein 6c: Transmembrane protein, putative 6l: Decapping nuclease 6t: Annexin 7a: Transmembrane protein, putative 7c: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial 7l: CTF/NF-I domain-containing protein a: Transmembrane protein, putative b: Protein phosphatase 2C, putative bp: Chromosome condensation regulator RCC1 repeat protein c1: Cytochrome c oxidase subunit 1 c2: Cytochrome c oxidase subunit 2 c3: Ymf68 d: SURF1-like protein e: TraB family protein f: Transmembrane protein, putative fs: Iron-binding zinc finger CDGSH type protein g: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8, mitochondrial h: SURF1-like protein i: COXTT9 j: COXTT10 k: 39S ribosomal protein L9, mitochondrial l: Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C m: Transmembrane protein, putative m1: Oxoglutarate/malate translocator protein, putative m2: 2-oxoglutarate/malate carrier protein m3: Carrier protein n: Transmembrane protein, putative o: Mobilization protein p: YflT domain-containing protein q: Transmembrane protein, putative r: Transmembrane protein s: Complex III subunit VII sa: Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial sb: Succinate dehydrogenase (quinone) sc: Cytochrome b-c1 complex subunit 8 sd: SDHD t: Transmembrane protein, putative u: Transmembrane protein, putative v: COXTT22 vb: Cytochrome C oxidase subunit Vb protein w: Transmembrane protein, putative x: Transmembrane protein, putative y: Lysozyme y0: Ymf70 y5: Ymf75 y7: Ymf67 z: ABC transporter z1: COXTT28 1b: NADH dehydrogenase subunit 1 2b: NADH dehydrogenase subunit 2 4l: Ymf58 5b: Ymf57 a1: Transmembrane protein, putative a2: Ribosomal protein L51/S25/CI-B8 domain protein a3: Transmembrane protein, putative a5: ETC complex I subunit motif protein a6: NADH dehydrogenase, putative a7: 37S ribosomal protein S25, mitochondrial a8: CX9C domain-containing protein a9: NAD-dependent epimerase/dehydratase family protein ab: Acyl carrier protein ac: Acyl carrier protein al: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 am: NDUA13 an: Transmembrane protein, putative b2: NDUB2 b3: Transmembrane protein, putative b4: NDUB4 b6: NDUB6 b7: CHCH domain-containing protein b8: NDUB8 b9: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial bl: NDUB10 bm: Transmembrane protein, putative c4: Complex I-MNLL fx: 2 iron, 2 sulfur cluster-binding protein g1: Gamma-carbonic anhydrase g2: Gamma-carbonic anhydrase g3: Transcription factor apfi protein, putative j1: DnaJ domain protein n1: NADH-ubiquinone oxidoreductase chain 1 n2: Ymf65 n3: NADH-ubiquinone oxidoreductase chain 3 n4: NADH-ubiquinone oxidoreductase chain 4 n5: NADH dehydrogenase subunit 5 n6: Ymf62 p1: Transmembrane protein, putative p2: NDUPH2 qA: M16 family peptidase, putative qB: Peptidase M16 inactive domain protein qC: Apocytochrome b qD: Cytochrome protein c1 qE: Rieske iron-sulfur protein, ubiquinol-cytochrome C reductase iron-sulfur subunit qF: Ubiquinol-cytochrome C reductase hinge protein qG: Sulphotransf domain-containing protein qH: Transmembrane protein, putative qI: Transmembrane protein, putative qJ: Transmembrane protein, putative qL: UQCRTT2 qM: Unknown peptide qa: M16 family peptidase, putative qb: Peptidase M16 inactive domain protein qc: Apocytochrome b qd: Cytochrome protein c1 qe: Rieske iron-sulfur protein, ubiquinol-cytochrome C reductase iron-sulfur subunit qf: Ubiquinol-cytochrome C reductase hinge protein qg: Sulphotransf domain-containing protein qh: Transmembrane protein, putative qi: Transmembrane protein, putative qj: Transmembrane protein, putative ql: UQCRTT2 qm: Unknown peptide s1: NADH-ubiquinone oxidoreductase 75 kDa subunit s2: NADH dehydrogenase subunit 7 s3: NADH dehydrogenase subunit 9 s4: NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial s5: GRAM domain protein s6: Zinc-finger protein s7: NADH dehydrogenase subunit 10 s8: NADH-ubiquinone oxidoreductase 1, chain, putative t1: Lipid-A-disaccharide synthase t2: Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II t3: RNase III domain-containing protein t4: Transmembrane protein t5: Transmembrane protein, putative t6: COX assembly mitochondrial protein t7: Transmembrane protein, putative t8: PH domain-containing protein t9: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 ta: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 tb: Transmembrane protein, putative tc: ATP synthase subunit e, mitochondrial td: Transmembrane protein, putative te: Transmembrane protein, putative tf: NDUTT15 tg: NDUTT16 th: NDUTT17 tx: Thioredoxin v1: NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial v2: NADH-ubiquinone oxidoreductase 24 kDa subunit x1: NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit 1T: Tim10/DDP family zinc finger protein 2E: NmrA domain-containing protein 2F: Transmembrane protein, putative 2G: SDHTT3 2H: Diphthamide synthesis protein 2I: DUF4885 domain-containing protein 2J: Transmembrane protein, putative 2K: Transmembrane protein, putative 2L: Transposase 2M: Transmembrane protein, putative 2N: Transmembrane protein, putative 2O: SDHTT11 2T: Zf-Tim10_DDP domain-containing protein 3T: Zf-Tim10_DDP domain-containing protein 4A: Phage protein 4T: Transposase 5T: Cullin domain-containing protein 6A: Transmembrane protein, putative 6B: Structural protein 6C: Transmembrane protein, putative 6L: Decapping nuclease 6T: Annexin 7A: Transmembrane protein, putative 7C: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial 7L: CTF/NF-I domain-containing protein A: Transmembrane protein, putative B: Protein phosphatase 2C, putative BP: Chromosome condensation regulator RCC1 repeat protein C1: Cytochrome c oxidase subunit 1 C2: Cytochrome c oxidase subunit 2 C3: Ymf68 D: SURF1-like protein E: TraB family protein F: Transmembrane protein, putative FS: Iron-binding zinc finger CDGSH type protein G: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8, mitochondrial H: SURF1-like protein I: COXTT9 J: COXTT10 K: 39S ribosomal protein L9, mitochondrial L: Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C M: Transmembrane protein, putative M1: Oxoglutarate/malate translocator protein, putative M2: 2-oxoglutarate/malate carrier protein M3: Carrier protein N: Transmembrane protein, putative O: Mobilization protein P: YflT domain-containing protein Q: Transmembrane protein, putative R: Transmembrane protein S: Complex III subunit VII SA: Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial SB: Succinate dehydrogenase (quinone) SC: Cytochrome b-c1 complex subunit 8 SD: SDHD T: Transmembrane protein, putative U: Transmembrane protein, putative V: COXTT22 VB: Cytochrome C oxidase subunit Vb protein W: Transmembrane protein, putative X: Transmembrane protein, putative Y: Lysozyme Y0: Ymf70 Y5: Ymf75 Y7: Ymf67 Z: ABC transporter Z1: COXTT28 1B: NADH dehydrogenase subunit 1 2B: NADH dehydrogenase subunit 2 4L: Ymf58 5B: Ymf57 A1: Transmembrane protein, putative A2: Ribosomal protein L51/S25/CI-B8 domain protein A3: Transmembrane protein, putative A5: ETC complex I subunit motif protein A6: NADH dehydrogenase, putative A7: 37S ribosomal protein S25, mitochondrial A8: CX9C domain-containing protein A9: NAD-dependent epimerase/dehydratase family protein AB: Acyl carrier protein AC: Acyl carrier protein AL: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 AM: NDUA13 AN: Transmembrane protein, putative B2: NDUB2 B3: Transmembrane protein, putative B4: NDUB4 B6: NDUB6 B7: CHCH domain-containing protein B8: NDUB8 B9: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial BL: NDUB10 BM: Transmembrane protein, putative C4: Complex I-MNLL FX: 2 iron, 2 sulfur cluster-binding protein G1: Gamma-carbonic anhydrase G2: Gamma-carbonic anhydrase G3: Transcription factor apfi protein, putative J1: DnaJ domain protein N1: NADH-ubiquinone oxidoreductase chain 1 N2: Ymf65 N3: NADH-ubiquinone oxidoreductase chain 3 N4: NADH-ubiquinone oxidoreductase chain 4 N5: NADH dehydrogenase subunit 5 N6: Ymf62 P1: Transmembrane protein, putative P2: NDUPH2 QA: M16 family peptidase, putative QB: Peptidase M16 inactive domain protein QC: Apocytochrome b QD: Cytochrome protein c1 QE: Rieske iron-sulfur protein, ubiquinol-cytochrome C reductase iron-sulfur subunit QF: Ubiquinol-cytochrome C reductase hinge protein QG: Sulphotransf domain-containing protein QH: Transmembrane protein, putative QI: Transmembrane protein, putative QJ: Transmembrane protein, putative QL: UQCRTT2 Qa: M16 family peptidase, putative Qb: Peptidase M16 inactive domain protein Qc: Apocytochrome b Qd: Cytochrome protein c1 Qe: Rieske iron-sulfur protein, ubiquinol-cytochrome C reductase iron-sulfur subunit Qf: Ubiquinol-cytochrome C reductase hinge protein Qg: Sulphotransf domain-containing protein Qh: Transmembrane protein, putative Qi: Transmembrane protein, putative Qj: Transmembrane protein, putative Ql: UQCRTT2 Qm: Unknown peptide S1: NADH-ubiquinone oxidoreductase 75 kDa subunit S2: NADH dehydrogenase subunit 7 S3: NADH dehydrogenase subunit 9 S4: NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial S5: GRAM domain protein S6: Zinc-finger protein S7: NADH dehydrogenase subunit 10 S8: NADH-ubiquinone oxidoreductase 1, chain, putative T1: Lipid-A-disaccharide synthase T2: Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II T3: RNase III domain-containing protein T4: Transmembrane protein T5: Transmembrane protein, putative T6: COX assembly mitochondrial protein T7: Transmembrane protein, putative T8: PH domain-containing protein T9: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 TA: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 TB: Transmembrane protein, putative TC: ATP synthase subunit e, mitochondrial TD: Transmembrane protein, putative TE: Transmembrane protein, putative TF: NDUTT15 TG: NDUTT16 TH: NDUTT17 TX: Thioredoxin V1: NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial V2: NADH-ubiquinone oxidoreductase 24 kDa subunit X1: NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit C: COXTT3 c: COXTT3 u1: Unknown peptide u2: Unknown peptide U2: Unknown peptide QM: Unknown peptide U1: Unknown peptide ヘテロ分子 ![]()
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要素
+タンパク質 , 79種, 170分子 1t1T2e2E2g2G2h2H2i2I2l2L4a4A4t4T5t5T6b6B6l6L6t6T7l7LbBbpBP...
#1: タンパク質 | 分子量: 8008.990 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: W7X3D6 ![]() ![]() ![]() ![]() #2: タンパク質 | 分子量: 36376.008 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q24I09 ![]() ![]() ![]() ![]() ![]() #4: タンパク質 | 分子量: 23627.730 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7MEX7 ![]() ![]() ![]() ![]() #5: タンパク質 | 分子量: 22894.336 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7LX66 ![]() ![]() ![]() ![]() ![]() #6: タンパク質 | 分子量: 12979.428 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q22YL0 ![]() ![]() ![]() ![]() #9: タンパク質 | 分子量: 11027.419 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: W7XBF5 ![]() ![]() ![]() ![]() #15: タンパク質 | 分子量: 14740.897 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q24C97 ![]() ![]() ![]() #16: タンパク質 | 分子量: 8081.111 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q22A35 ![]() ![]() ![]() #17: タンパク質 | 分子量: 8965.917 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q22N23 ![]() ![]() ![]() #19: タンパク質 | 分子量: 27946.445 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q24I72 ![]() ![]() ![]() ![]() ![]() #21: タンパク質 | 分子量: 10200.682 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7LVX0 ![]() ![]() ![]() ![]() #22: タンパク質 | 分子量: 8155.360 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q233U0 ![]() ![]() ![]() #25: タンパク質 | 分子量: 116812.750 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q22CI1 ![]() ![]() ![]() ![]() ![]() #27: タンパク質 | 分子量: 53011.297 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q22FX8 ![]() ![]() ![]() ![]() #28: タンパク質 | 分子量: 50912.336 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences ![]() ![]() #31: タンパク質 | 分子量: 72782.539 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q950Y6 ![]() ![]() ![]() ![]() #32: タンパク質 | 分子量: 47087.973 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7M1Q4 ![]() ![]() ![]() ![]() #33: タンパク質 | 分子量: 45022.914 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q23DP7 ![]() ![]() ![]() ![]() #35: タンパク質 | 分子量: 21476.887 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7M8P0 ![]() ![]() ![]() ![]() ![]() #37: タンパク質 | 分子量: 35794.367 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7LTZ4 ![]() ![]() ![]() ![]() #38: タンパク質 | 分子量: 29865.686 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7LY65 ![]() ![]() ![]() ![]() #39: タンパク質 | 分子量: 28101.486 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7MD70 ![]() ![]() ![]() #40: タンパク質 | 分子量: 27034.711 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: W7X4J9 ![]() ![]() ![]() ![]() #43: タンパク質 | 分子量: 40392.234 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: A4VDV3 ![]() ![]() ![]() ![]() #44: タンパク質 | 分子量: 36090.277 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q23M99 ![]() ![]() ![]() ![]() #45: タンパク質 | 分子量: 37095.141 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q22ZA6 ![]() ![]() ![]() ![]() #47: タンパク質 | 分子量: 23257.660 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q23F08 ![]() ![]() ![]() ![]() #48: タンパク質 | 分子量: 19979.320 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7M8Y9 ![]() ![]() ![]() ![]() #51: タンパク質 | 分子量: 19882.758 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q230X6 ![]() ![]() ![]() ![]() #54: タンパク質 | 分子量: 7036.020 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q23RH8 ![]() ![]() ![]() ![]() #58: タンパク質 | 分子量: 17701.115 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7MFV5 ![]() ![]() ![]() #62: タンパク質 | 分子量: 12273.913 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7M9E7 ![]() ![]() ![]() ![]() ![]() #63: タンパク質 | 分子量: 10891.920 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q950Y0 ![]() ![]() ![]() #64: タンパク質 | 分子量: 23325.801 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q951A7 ![]() ![]() ![]() ![]() #65: タンパク質 | 分子量: 54538.531 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q950Y7 ![]() ![]() ![]() ![]() #66: タンパク質 | 分子量: 10418.697 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7LTF1 ![]() ![]() ![]() #67: タンパク質 | 分子量: 11121.555 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences ![]() #70: タンパク質 | 分子量: 13509.949 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q950Z5 ![]() ![]() ![]() #71: タンパク質 | 分子量: 12473.938 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q951C2 ![]() ![]() ![]() ![]() #73: タンパク質 | 分子量: 12157.782 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7MA77 ![]() ![]() ![]() #75: タンパク質 | 分子量: 24277.859 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q23ND5 ![]() ![]() ![]() ![]() #76: タンパク質 | 分子量: 20167.854 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7M2Y3 ![]() ![]() ![]() ![]() #77: タンパク質 | 分子量: 33201.797 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7MIJ7 ![]() ![]() ![]() ![]() #78: タンパク質 | 分子量: 28412.805 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7MMF4 ![]() ![]() ![]() ![]() ![]() #79: タンパク質 | 分子量: 41375.090 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7MLH2 ![]() ![]() ![]() ![]() #83: タンパク質 | 分子量: 21045.617 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7M2U4 ![]() ![]() ![]() ![]() #85: タンパク質 | 分子量: 14410.395 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7MG29 ![]() ![]() ![]() ![]() #87: タンパク質 | 分子量: 17502.564 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences ![]() ![]() #88: タンパク質 | 分子量: 15444.344 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q231G0 ![]() ![]() ![]() #89: タンパク質 | 分子量: 13747.362 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7MIM0 ![]() ![]() ![]() ![]() #90: タンパク質 | 分子量: 24150.469 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7M855 ![]() ![]() ![]() ![]() #92: タンパク質 | 分子量: 22167.137 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q23KG0 ![]() ![]() ![]() ![]() #94: タンパク質 | 分子量: 12103.036 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q22W63 ![]() ![]() ![]() ![]() #95: タンパク質 | 分子量: 19564.221 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q22W11 ![]() ![]() ![]() ![]() ![]() #98: タンパク質 | 分子量: 39793.414 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7M8Q7 ![]() ![]() ![]() ![]() #99: タンパク質 | 分子量: 36878.367 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q22DR7 ![]() ![]() ![]() ![]() #101: タンパク質 | 分子量: 43104.082 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q951A3 ![]() ![]() ![]() ![]() #105: タンパク質 | 分子量: 30448.471 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q950Y2 ![]() ![]() ![]() ![]() #107: タンパク質 | 分子量: 22446.637 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q23KE0 ![]() ![]() ![]() ![]() #108: タンパク質 | 分子量: 53030.543 Da / 分子数: 4 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7MJ25 ![]() ![]() ![]() ![]() #109: タンパク質 | 分子量: 58023.914 Da / 分子数: 4 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7MGU2 ![]() ![]() ![]() ![]() #110: タンパク質 | 分子量: 50635.547 Da / 分子数: 4 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q950Z1, quinol-cytochrome-c reductase ![]() ![]() ![]() ![]() ![]() #111: タンパク質 | 分子量: 37616.629 Da / 分子数: 4 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q24IM5 ![]() ![]() ![]() ![]() ![]() #112: タンパク質 | 分子量: 30696.961 Da / 分子数: 4 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7MIC7 ![]() ![]() ![]() ![]() #114: タンパク質 | 分子量: 39193.523 Da / 分子数: 4 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q23F81 ![]() ![]() ![]() ![]() #124: タンパク質 | 分子量: 10920.431 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: W7X4R4 ![]() ![]() ![]() ![]() ![]() #125: タンパク質 | 分子量: 15141.296 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7MK02 ![]() ![]() ![]() ![]() ![]() #128: タンパク質 | 分子量: 59307.289 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q22E24, lipid-A-disaccharide synthase ![]() ![]() ![]() ![]() #129: タンパク質 | 分子量: 36709.441 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q24HK5 ![]() ![]() ![]() ![]() #130: タンパク質 | 分子量: 35409.246 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() 参照: UniProt: I7LUQ4 ![]() ![]() ![]() ![]() #133: タンパク質 | 分子量: 17078.342 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: I7M1N8 ![]() ![]() ![]() ![]() ![]() #135: タンパク質 | 分子量: 15785.234 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q22SC4 ![]() ![]() ![]() ![]() #139: タンパク質 | 分子量: 11283.534 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q22E95 ![]() ![]() ![]() ![]() #142: タンパク質 | 分子量: 27562.686 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences ![]() ![]() #143: タンパク質 | 分子量: 15465.568 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences ![]() ![]() #144: タンパク質 | 分子量: 14124.288 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() ![]() ![]() #145: タンパク質 | 分子量: 19540.191 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences 参照: UniProt: Q22AI5 ![]() ![]() ![]() #149: タンパク質 | 分子量: 23368.416 Da / 分子数: 2 / 由来タイプ: 天然 由来: (天然) ![]() Plasmid details: Institute of Hydrobiology, Chinese Academy of Sciences ![]() ![]() #150: タンパク質 | |
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