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Yorodumi- PDB-1atl: Structural interaction of natural and synthetic inhibitors with t... -
+Open data
-Basic information
Entry | Database: PDB / ID: 1atl | ||||||
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Title | Structural interaction of natural and synthetic inhibitors with the VENOM METALLOPROTEINASE, ATROLYSIN C (FORM-D) | ||||||
Components | Snake venom metalloproteinase atrolysin-D | ||||||
Keywords | HYDROLASE/HYDROLASE INHIBITOR / METALLOENDOPEPTIDASE / HYDROLASE-HYDROLASE INHIBITOR complex | ||||||
Function / homology | Function and homology information atrolysin C / collagen catabolic process / metalloendopeptidase activity / toxin activity / proteolysis / extracellular region / metal ion binding / plasma membrane Similarity search - Function | ||||||
Biological species | Crotalus atrox (western diamondback rattlesnake) | ||||||
Method | X-RAY DIFFRACTION / Resolution: 1.8 Å | ||||||
Authors | Zhang, D. / Botos, I. / Gomis-Rueth, F.-X. / Doll, R. / Blood, C. / Njoroge, F.G. / Fox, J.W. / Bode, W. / Meyer, E.F. | ||||||
Citation | Journal: Proc.Natl.Acad.Sci.USA / Year: 1994 Title: Structural interaction of natural and synthetic inhibitors with the venom metalloproteinase, atrolysin C (form d). Authors: Zhang, D. / Botos, I. / Gomis-Ruth, F.X. / Doll, R. / Blood, C. / Njoroge, F.G. / Fox, J.W. / Bode, W. / Meyer, E.F. #1: Journal: J.Mol.Biol. / Year: 1995 Title: Structure of a Retro-Binding Peptide Inhibitor Complexed with Human Alpha-Thrombin Authors: Tabernero, L. / Chang, C.Y. / Ohringer, S.L. / Lau, W.F. / Iwanowicz, E.J. / Han, W.C. / Wang, T.C. / Seiler, S.M. / Roberts, D.G. / Sack, J.S. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1atl.cif.gz | 96.2 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1atl.ent.gz | 73.8 KB | Display | PDB format |
PDBx/mmJSON format | 1atl.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 1atl_validation.pdf.gz | 1023.3 KB | Display | wwPDB validaton report |
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Full document | 1atl_full_validation.pdf.gz | 1 MB | Display | |
Data in XML | 1atl_validation.xml.gz | 18.3 KB | Display | |
Data in CIF | 1atl_validation.cif.gz | 25.1 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/at/1atl ftp://data.pdbj.org/pub/pdb/validation_reports/at/1atl | HTTPS FTP |
-Related structure data
-Links
-Assembly
Deposited unit |
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1 |
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2 |
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Unit cell |
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Atom site foot note | 1: CIS PROLINE - PRO A 202 |
-Components
#1: Protein | Mass: 23147.254 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Details: ISOLATED FROM VENOM Source: (natural) Crotalus atrox (western diamondback rattlesnake) References: UniProt: P15167, atrolysin C #2: Chemical | #3: Chemical | #4: Chemical | #5: Water | ChemComp-HOH / | Compound details | THE METHYL-TYROSINE SIDECHAIN MAKES A DEEP INSERTION INTO THE ENZYME'S S1' PRIMARY SPECIFICIT | |
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-Experimental details
-Experiment
Experiment | Method: X-RAY DIFFRACTION |
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-Sample preparation
Crystal | Density Matthews: 2.55 Å3/Da / Density % sol: 51.86 % | ||||||||||||||||||||||||||||||
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Crystal grow | *PLUS pH: 6.8 / Method: vapor diffusion | ||||||||||||||||||||||||||||||
Components of the solutions | *PLUS
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-Data collection
Radiation | Scattering type: x-ray |
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Radiation wavelength | Relative weight: 1 |
-Processing
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Refinement | Resolution: 1.8→8 Å /
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Refinement step | Cycle: LAST / Resolution: 1.8→8 Å
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Refine LS restraints |
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