+Open data
-Basic information
Entry | Database: PDB / ID: 7q6n | ||||||
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Title | Structure of WrbA from Salmonella Typhimurium bound to ME0052 | ||||||
Components | NAD(P)H dehydrogenase (quinone) | ||||||
Keywords | FLAVOPROTEIN / NADH dehydrogenase / oxidoreductase / anti-virulence compound | ||||||
Function / homology | Function and homology information NAD(P)H dehydrogenase (quinone) / NADPH dehydrogenase (quinone) activity / NADH:ubiquinone reductase (non-electrogenic) activity / NAD binding / FMN binding / flavin adenine dinucleotide binding / NADP binding Similarity search - Function | ||||||
Biological species | Salmonella enterica subsp. enterica serovar Typhimurium (bacteria) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.33 Å | ||||||
Authors | Gabrielsen, M. / Beckham, K.S.H. / Roe, A.J. | ||||||
Funding support | 1items
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Citation | Journal: Microbiology (Reading, Engl.) / Year: 2022 Title: Crystal structures of WrbA, a spurious target of the salicylidene acylhydrazide inhibitors of type III secretion in Gram-negative pathogens, and verification of improved specificity of next-generation compounds. Authors: Zambelloni, R. / Beckham, K.S.H. / Wu, H.J. / Elofsson, M. / Marquez, R. / Gabrielsen, M. / Roe, A.J. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7q6n.cif.gz | 535.1 KB | Display | PDBx/mmCIF format |
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PDB format | pdb7q6n.ent.gz | 373.9 KB | Display | PDB format |
PDBx/mmJSON format | 7q6n.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 7q6n_validation.pdf.gz | 3 MB | Display | wwPDB validaton report |
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Full document | 7q6n_full_validation.pdf.gz | 3.1 MB | Display | |
Data in XML | 7q6n_validation.xml.gz | 34.1 KB | Display | |
Data in CIF | 7q6n_validation.cif.gz | 45.9 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/q6/7q6n ftp://data.pdbj.org/pub/pdb/validation_reports/q6/7q6n | HTTPS FTP |
-Related structure data
Related structure data | 7q6mC 7q6oC 2r96S S: Starting model for refinement C: citing same article (ref.) |
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Similar structure data | Similarity search - Function & homologyF&H Search |
-Links
-Assembly
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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