登録情報 | データベース: PDB / ID: 6d4o |
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タイトル | Eubacterium eligens beta-glucuronidase bound to an amoxapine-glucuronide conjugate |
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要素 | Beta-glucuronidase |
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キーワード | HYDROLASE / Glycosyl hydrolase |
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機能・相同性 | 機能・相同性情報
: / beta-glucuronidase / beta-glucuronidase activity / beta-galactosidase activity / carbohydrate binding / carbohydrate metabolic process / signaling receptor binding / extracellular space類似検索 - 分子機能 Glycoside hydrolase, family 2, active site / Glycosyl hydrolases family 2 acid/base catalyst. / Glycoside hydrolase, family 2, conserved site / Glycosyl hydrolases family 2 signature 1. / Glycoside hydrolase, family 2 / Glycoside hydrolase family 2, catalytic domain / Glycosyl hydrolases family 2, TIM barrel domain / Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich / Glycosyl hydrolases family 2, sugar binding domain / Glycosyl hydrolases family 2 ...Glycoside hydrolase, family 2, active site / Glycosyl hydrolases family 2 acid/base catalyst. / Glycoside hydrolase, family 2, conserved site / Glycosyl hydrolases family 2 signature 1. / Glycoside hydrolase, family 2 / Glycoside hydrolase family 2, catalytic domain / Glycosyl hydrolases family 2, TIM barrel domain / Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich / Glycosyl hydrolases family 2, sugar binding domain / Glycosyl hydrolases family 2 / Glycosyl hydrolases family 2, sugar binding domain / Beta-Galactosidase/glucuronidase domain superfamily / Galactose-binding domain-like / Galactose-binding-like domain superfamily / Glycosidases / Glycoside hydrolase superfamily / Jelly Rolls / Immunoglobulins / TIM Barrel / Alpha-Beta Barrel / Immunoglobulin-like fold / Immunoglobulin-like / Sandwich / Mainly Beta / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | [Eubacterium] eligens (バクテリア) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.9 Å |
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データ登録者 | Pellock, S.J. / Walton, W.G. / Redinbo, M.R. |
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資金援助 | 米国, 2件 組織 | 認可番号 | 国 |
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National Institutes of Health/National Cancer Institute (NIH/NCI) | CA098468 | 米国 | National Institutes of Health/National Cancer Institute (NIH/NCI) | CA207416 | 米国 |
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引用 | ジャーナル: ACS Cent Sci / 年: 2018 タイトル: Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception. 著者: Pellock, S.J. / Creekmore, B.C. / Walton, W.G. / Mehta, N. / Biernat, K.A. / Cesmat, A.P. / Ariyarathna, Y. / Dunn, Z.D. / Li, B. / Jin, J. / James, L.I. / Redinbo, M.R. |
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履歴 | 登録 | 2018年4月18日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2018年7月25日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2018年8月22日 | Group: Data collection / Database references / カテゴリ: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year / _citation_author.name |
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改定 1.2 | 2019年12月4日 | Group: Author supporting evidence / カテゴリ: pdbx_audit_support / Item: _pdbx_audit_support.funding_organization |
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改定 1.3 | 2024年3月13日 | Group: Data collection / Database references / カテゴリ: chem_comp_atom / chem_comp_bond / database_2 Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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