Entry | Database: PDB / ID: 5jtt |
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Title | Crystal structure of GPb in complex with 8a |
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Components | Glycogen phosphorylase, muscle form |
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Keywords | TRANSFERASE / alpha and beta protein transferase |
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Function / homology | Function and homology information
glycogen phosphorylase / glycogen phosphorylase activity / linear malto-oligosaccharide phosphorylase activity / SHG alpha-glucan phosphorylase activity / glycogen catabolic process / skeletal muscle myofibril / pyridoxal phosphate binding / nucleotide bindingSimilarity search - Function Glycosyl transferase, family 35 / Glycogen/starch/alpha-glucan phosphorylase / Phosphorylase pyridoxal-phosphate attachment site / Carbohydrate phosphorylase / Phosphorylase pyridoxal-phosphate attachment site. / Glycogen Phosphorylase B; / Rossmann fold / 3-Layer(aba) Sandwich / Alpha BetaSimilarity search - Domain/homology |
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Biological species | ![](img/tx_mammal.gif) Oryctolagus cuniculus (rabbit) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / FOURIER SYNTHESIS / Resolution: 1.85 Å |
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Authors | Kantsadi, A.L. / Stravodimos, G.A. / Chatzileontiadou, D.S.M. / Leonidas, D.D. |
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Citation | Journal: Eur.J.Med.Chem. / Year: 2016 Title: Synthetic, enzyme kinetic, and protein crystallographic studies of C-beta-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase. Authors: Kantsadi, A.L. / Bokor, E. / Kun, S. / Stravodimos, G.A. / Chatzileontiadou, D.S. / Leonidas, D.D. / Juhasz-Toth, E. / Szakacs, A. / Batta, G. / Docsa, T. / Gergely, P. / Somsak, L. |
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History | Deposition | May 9, 2016 | Deposition site: RCSB / Processing site: PDBE |
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Revision 1.0 | Aug 24, 2016 | Provider: repository / Type: Initial release |
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Revision 1.1 | Jan 17, 2018 | Group: Data collection / Category: diffrn_source / Item: _diffrn_source.pdbx_synchrotron_site |
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