登録情報 データベース : PDB / ID : 4tw8 構造の表示 ダウンロードとリンクタイトル The Fk1-Fk2 domains of FKBP52 in complex with iFit-FL 要素Peptidyl-prolyl cis-trans isomerase FKBP4 詳細 キーワード ISOMERASE / Fk-506 binding domain / Hsp90 cochaperone / immunophiline / peptidyl-prolyl isomerase / ligand selectivity機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
steroid hormone receptor complex assembly / negative regulation of microtubule polymerization or depolymerization / male sex differentiation / copper-dependent protein binding / prostate gland development / copper ion transport / nuclear glucocorticoid receptor binding / protein-containing complex localization / negative regulation of microtubule polymerization / FK506 binding ... steroid hormone receptor complex assembly / negative regulation of microtubule polymerization or depolymerization / male sex differentiation / copper-dependent protein binding / prostate gland development / copper ion transport / nuclear glucocorticoid receptor binding / protein-containing complex localization / negative regulation of microtubule polymerization / FK506 binding / androgen receptor signaling pathway / Attenuation phase / axonal growth cone / chaperone-mediated protein folding / heat shock protein binding / HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand / embryo implantation / ESR-mediated signaling / peptidylprolyl isomerase / peptidyl-prolyl cis-trans isomerase activity / phosphoprotein binding / tau protein binding / negative regulation of neuron projection development / protein folding / protein-macromolecule adaptor activity / Potential therapeutics for SARS / Estrogen-dependent gene expression / microtubule / neuronal cell body / GTP binding / perinuclear region of cytoplasm / protein-containing complex / mitochondrion / RNA binding / extracellular exosome / nucleoplasm / ATP binding / cytoplasm / cytosol 類似検索 - 分子機能 Tetratricopeptide repeat 2 / Tetratricopeptide repeat / : / Chitinase A; domain 3 - #40 / Tetratricopeptide repeat / Chitinase A; domain 3 / FKBP-type peptidyl-prolyl cis-trans isomerase domain profile. / FKBP-type peptidyl-prolyl cis-trans isomerase domain / FKBP-type peptidyl-prolyl cis-trans isomerase / Peptidyl-prolyl cis-trans isomerase domain superfamily ... Tetratricopeptide repeat 2 / Tetratricopeptide repeat / : / Chitinase A; domain 3 - #40 / Tetratricopeptide repeat / Chitinase A; domain 3 / FKBP-type peptidyl-prolyl cis-trans isomerase domain profile. / FKBP-type peptidyl-prolyl cis-trans isomerase domain / FKBP-type peptidyl-prolyl cis-trans isomerase / Peptidyl-prolyl cis-trans isomerase domain superfamily / TPR repeat region circular profile. / TPR repeat profile. / Tetratricopeptide repeats / Tetratricopeptide repeat / Tetratricopeptide-like helical domain superfamily / Roll / Alpha Beta 類似検索 - ドメイン・相同性 Chem-37M / Peptidyl-prolyl cis-trans isomerase FKBP4 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 3.003 Å 詳細データ登録者 Gaali, S. / Kirschner, A. / Cuboni, S. / Hartmann, J. / Kozany, C. / Balsevich, G. / Namendorf, C. / Fernandez-Vizarra, P. / Almeida, O.F.X. / Ruehter, G. ...Gaali, S. / Kirschner, A. / Cuboni, S. / Hartmann, J. / Kozany, C. / Balsevich, G. / Namendorf, C. / Fernandez-Vizarra, P. / Almeida, O.F.X. / Ruehter, G. / Uhr, M. / Schmidt, M.V. / Touma, C. / Bracher, A. / Hausch, F. 引用ジャーナル : Nat.Chem.Biol. / 年 : 2015タイトル : Selective inhibitors of the FK506-binding protein 51 by induced fit.
著者: Gaali, S. / Kirschner, A. / Cuboni, S. / Hartmann, J. / Kozany, C. / Balsevich, G. / Namendorf, C. / Fernandez-Vizarra, P. / Sippel, C. / Zannas, A.S. / Draenert, R. / Binder, E.B. / Almeida, ... 著者 : Gaali, S. / Kirschner, A. / Cuboni, S. / Hartmann, J. / Kozany, C. / Balsevich, G. / Namendorf, C. / Fernandez-Vizarra, P. / Sippel, C. / Zannas, A.S. / Draenert, R. / Binder, E.B. / Almeida, O.F. / Ruhter, G. / Uhr, M. / Schmidt, M.V. / Touma, C. / Bracher, A. / Hausch, F. 残り1件を表示 表示を減らす履歴 登録 2014年6月30日 登録サイト : RCSB / 処理サイト : PDBE改定 1.0 2014年11月26日 Provider : repository / タイプ : Initial release改定 1.1 2014年12月10日 Group : Database references改定 1.2 2014年12月24日 Group : Database references改定 1.3 2023年12月20日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ncs_dom_lim Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id
すべて表示 表示を減らす