登録情報 データベース : PDB / ID : 4.0E+92 構造の表示 ダウンロードとリンクタイトル Crystal Structure of the N-Terminal Domain of HIV-1 Capsid in Complex With Inhibitor BM4 要素Gag protein 詳細 キーワード STRUCTURAL PROTEIN/INHIBITOR / Structural protein Capsid / STRUCTURAL PROTEIN-INHIBITOR complex機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
viral budding via host ESCRT complex / HIV-1 retropepsin / symbiont-mediated activation of host apoptosis / retroviral ribonuclease H / exoribonuclease H / exoribonuclease H activity / host multivesicular body / DNA integration / viral genome integration into host DNA / RNA-directed DNA polymerase ... viral budding via host ESCRT complex / HIV-1 retropepsin / symbiont-mediated activation of host apoptosis / retroviral ribonuclease H / exoribonuclease H / exoribonuclease H activity / host multivesicular body / DNA integration / viral genome integration into host DNA / RNA-directed DNA polymerase / establishment of integrated proviral latency / viral penetration into host nucleus / RNA stem-loop binding / symbiont-mediated suppression of host gene expression / RNA-directed DNA polymerase activity / host cell / RNA-DNA hybrid ribonuclease activity / 転移酵素; リンを含む基を移すもの; 核酸を移すもの / viral nucleocapsid / aspartic-type endopeptidase activity / DNA recombination / host cell cytoplasm / DNA-directed DNA polymerase / 加水分解酵素; エステル加水分解酵素 / DNA-directed DNA polymerase activity / symbiont entry into host cell / lipid binding / host cell nucleus / host cell plasma membrane / structural molecule activity / virion membrane / proteolysis / DNA binding / RNA binding / zinc ion binding / identical protein binding / membrane / cytoplasm 類似検索 - 分子機能 Human Immunodeficiency Virus Type 1 Capsid Protein / Human Immunodeficiency Virus Type 1 Capsid Protein / Gag protein p6 / Gag protein p6 / : / gag protein p24 N-terminal domain / Reverse transcriptase connection / Reverse transcriptase connection domain / Reverse transcriptase thumb / Reverse transcriptase thumb domain ... Human Immunodeficiency Virus Type 1 Capsid Protein / Human Immunodeficiency Virus Type 1 Capsid Protein / Gag protein p6 / Gag protein p6 / : / gag protein p24 N-terminal domain / Reverse transcriptase connection / Reverse transcriptase connection domain / Reverse transcriptase thumb / Reverse transcriptase thumb domain / Integrase Zinc binding domain / Zinc finger integrase-type profile. / Integrase-like, N-terminal / Integrase DNA binding domain / Integrase, C-terminal domain superfamily, retroviral / Integrase, N-terminal zinc-binding domain / Integrase, C-terminal, retroviral / Integrase DNA binding domain profile. / Immunodeficiency lentiviral matrix, N-terminal / gag gene protein p17 (matrix protein) / RNase H / Integrase core domain / Integrase, catalytic core / Integrase catalytic domain profile. / Retroviral nucleocapsid Gag protein p24, C-terminal domain / Gag protein p24 C-terminal domain / Retropepsin-like catalytic domain / Matrix protein, lentiviral and alpha-retroviral, N-terminal / Ribonuclease H domain / RNase H type-1 domain profile. / Reverse transcriptase (RNA-dependent DNA polymerase) / Reverse transcriptase domain / Reverse transcriptase (RT) catalytic domain profile. / Retropepsins / Retroviral aspartyl protease / Aspartyl protease, retroviral-type family profile. / Peptidase A2A, retrovirus, catalytic / Retrovirus capsid, C-terminal / Retroviral matrix protein / Retrovirus capsid, N-terminal / zinc finger / Zinc knuckle / Zinc finger, CCHC-type superfamily / Zinc finger, CCHC-type / Zinc finger CCHC-type profile. / Aspartic peptidase, active site / Eukaryotic and viral aspartyl proteases active site. / Aspartic peptidase domain superfamily / Ribonuclease H superfamily / Ribonuclease H-like superfamily / Reverse transcriptase/Diguanylate cyclase domain / DNA/RNA polymerase superfamily / Orthogonal Bundle / Mainly Alpha 類似検索 - ドメイン・相同性 Chem-0OE / Chem-0OG / Gag-Pol polyprotein / Gag polyprotein 類似検索 - 構成要素生物種 Human immunodeficiency virus 1 (ヒト免疫不全ウイルス)手法 X線回折 / 分子置換 / 解像度 : 1.8 Å 詳細データ登録者 Lemke, C.T. 引用ジャーナル : J.Virol. / 年 : 2012タイトル : Distinct Effects of Two HIV-1 Capsid Assembly Inhibitor Families That Bind the Same Site within the N-Terminal Domain of the Viral CA Protein.
著者: Lemke, C.T. / Titolo, S. / von Schwedler, U. / Goudreau, N. / Mercier, J.F. / Wardrop, E. / Faucher, A.M. / Coulombe, R. / Banik, S.S. / Fader, L. / Gagnon, A. / Kawai, S.H. / Rancourt, J. / ... 著者 : Lemke, C.T. / Titolo, S. / von Schwedler, U. / Goudreau, N. / Mercier, J.F. / Wardrop, E. / Faucher, A.M. / Coulombe, R. / Banik, S.S. / Fader, L. / Gagnon, A. / Kawai, S.H. / Rancourt, J. / Tremblay, M. / Yoakim, C. / Simoneau, B. / Archambault, J. / Sundquist, W.I. / Mason, S.W. 残り1件を表示 表示を減らす履歴 登録 2012年3月20日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2012年4月25日 Provider : repository / タイプ : Initial release改定 1.1 2012年6月6日 Group : Database references改定 1.2 2013年6月12日 Group : Database references改定 1.3 2024年2月28日 Group : Data collection / Database references / Derived calculationsカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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