登録情報 データベース : PDB / ID : 3qak 構造の表示 ダウンロードとリンクタイトル Agonist bound structure of the human adenosine A2a receptor 要素Adenosine receptor A2a,lysozyme chimera 詳細 キーワード SIGNALING PROTEIN / HYDROLASE / Structural Genomics / Protein Structure Initiative / JOINT CENTER FOR INNOVATIVE MEMBRANE PROTEIN TECHNOLOGIES / JCIMPT / Membrane protein / receptor / GPCR Network / GPCR / PSI-Biology機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
positive regulation of acetylcholine secretion, neurotransmission / positive regulation of circadian sleep/wake cycle, sleep / regulation of norepinephrine secretion / negative regulation of alpha-beta T cell activation / Adenosine P1 receptors / G protein-coupled adenosine receptor activity / G protein-coupled adenosine receptor signaling pathway / response to purine-containing compound / sensory perception / NGF-independant TRKA activation ... positive regulation of acetylcholine secretion, neurotransmission / positive regulation of circadian sleep/wake cycle, sleep / regulation of norepinephrine secretion / negative regulation of alpha-beta T cell activation / Adenosine P1 receptors / G protein-coupled adenosine receptor activity / G protein-coupled adenosine receptor signaling pathway / response to purine-containing compound / sensory perception / NGF-independant TRKA activation / Surfactant metabolism / positive regulation of urine volume / synaptic transmission, dopaminergic / : / inhibitory postsynaptic potential / negative regulation of vascular permeability / type 5 metabotropic glutamate receptor binding / synaptic transmission, cholinergic / blood circulation / positive regulation of glutamate secretion / response to caffeine / intermediate filament / eating behavior / alpha-actinin binding / presynaptic active zone / regulation of calcium ion transport / membrane depolarization / asymmetric synapse / axolemma / : / cellular defense response / prepulse inhibition / phagocytosis / viral release from host cell by cytolysis / response to amphetamine / presynaptic modulation of chemical synaptic transmission / peptidoglycan catabolic process / positive regulation of synaptic transmission, glutamatergic / neuron projection morphogenesis / excitatory postsynaptic potential / positive regulation of apoptotic signaling pathway / regulation of mitochondrial membrane potential / synaptic transmission, glutamatergic / positive regulation of long-term synaptic potentiation / central nervous system development / locomotory behavior / positive regulation of synaptic transmission, GABAergic / positive regulation of protein secretion / astrocyte activation / apoptotic signaling pathway / adenylate cyclase-modulating G protein-coupled receptor signaling pathway / adenylate cyclase-activating G protein-coupled receptor signaling pathway / negative regulation of inflammatory response / vasodilation / blood coagulation / cell wall macromolecule catabolic process / lysozyme / cell-cell signaling / lysozyme activity / presynaptic membrane / G alpha (s) signalling events / postsynaptic membrane / negative regulation of neuron apoptotic process / host cell cytoplasm / calmodulin binding / defense response to bacterium / response to xenobiotic stimulus / inflammatory response / negative regulation of cell population proliferation / neuronal cell body / lipid binding / glutamatergic synapse / dendrite / regulation of DNA-templated transcription / protein-containing complex binding / apoptotic process / enzyme binding / identical protein binding / membrane / plasma membrane 類似検索 - 分子機能 Adenosine A2A receptor / Adenosine receptor / Rhopdopsin 7-helix transmembrane proteins / Rhodopsin 7-helix transmembrane proteins / Lysozyme - #40 / Endolysin T4 type / : / T4-type lysozyme / Glycoside hydrolase, family 24 / Lysozyme domain superfamily ... Adenosine A2A receptor / Adenosine receptor / Rhopdopsin 7-helix transmembrane proteins / Rhodopsin 7-helix transmembrane proteins / Lysozyme - #40 / Endolysin T4 type / : / T4-type lysozyme / Glycoside hydrolase, family 24 / Lysozyme domain superfamily / Phage lysozyme / Serpentine type 7TM GPCR chemoreceptor Srsx / Lysozyme / G-protein coupled receptors family 1 signature. / G protein-coupled receptor, rhodopsin-like / GPCR, rhodopsin-like, 7TM / G-protein coupled receptors family 1 profile. / 7 transmembrane receptor (rhodopsin family) / Lysozyme-like domain superfamily / Up-down Bundle / Orthogonal Bundle / Mainly Alpha 類似検索 - ドメイン・相同性 (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate / Chem-UKA / Endolysin / Adenosine receptor A2a 類似検索 - 構成要素生物種 Homo Sapien (ヒト) Enterobacteria phage T4 (ファージ)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.71 Å 詳細データ登録者 Xu, F. / Wu, H. / Katritch, V. / Han, G.W. / Cherezov, V. / Stevens, R. / GPCR Network (GPCR) 引用ジャーナル : Science / 年 : 2011タイトル : Structure of an agonist-bound human A2A adenosine receptor.著者 : Xu, F. / Wu, H. / Katritch, V. / Han, G.W. / Jacobson, K.A. / Gao, Z.G. / Cherezov, V. / Stevens, R.C. 履歴 登録 2011年1月11日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2011年3月9日 Provider : repository / タイプ : Initial release改定 1.1 2011年7月13日 Group : Version format compliance改定 1.2 2012年5月2日 Group : Structure summary改定 1.3 2012年10月10日 Group : Database references改定 1.4 2017年7月26日 Group : Refinement description / Source and taxonomy / カテゴリ : entity_src_gen / software改定 1.5 2018年1月24日 Group : Structure summary / カテゴリ : audit_author
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