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- EMDB-35230: In situ structure of axonemal doublet microtubules in mouse sperm... -

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基本情報

登録情報
データベース: EMDB / ID: EMD-35230
タイトルIn situ structure of axonemal doublet microtubules in mouse sperm with 48-nm repeat
マップデータIn situ structure of axonemal doublet microtubules in mouse sperm with 48-nm repeat
試料
  • 細胞: mouse sperm
    • タンパク質・ペプチド: x 38種
  • リガンド: x 1種
キーワードmicrotubules / axoneme / sperm / filament / STRUCTURAL PROTEIN
機能・相同性
機能・相同性情報


male germ-line stem cell population maintenance / axonemal microtubule doublet inner sheath / epithelial cilium movement involved in determination of left/right asymmetry / left/right pattern formation / sperm flagellum assembly / establishment of left/right asymmetry / 9+0 motile cilium / Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane / Cilium Assembly / Sealing of the nuclear envelope (NE) by ESCRT-III ...male germ-line stem cell population maintenance / axonemal microtubule doublet inner sheath / epithelial cilium movement involved in determination of left/right asymmetry / left/right pattern formation / sperm flagellum assembly / establishment of left/right asymmetry / 9+0 motile cilium / Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane / Cilium Assembly / Sealing of the nuclear envelope (NE) by ESCRT-III / outer acrosomal membrane / regulation of brood size / protein localization to motile cilium / manchette assembly / axonemal B tubule inner sheath / regulation of calcineurin-NFAT signaling cascade / inner dynein arm assembly / Intraflagellar transport / axonemal A tubule inner sheath / Carboxyterminal post-translational modifications of tubulin / sperm axoneme assembly / protein polyglutamylation / positive regulation of feeding behavior / sperm principal piece / COPI-independent Golgi-to-ER retrograde traffic / cerebrospinal fluid circulation / cilium-dependent cell motility / HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand / MAP kinase tyrosine/serine/threonine phosphatase activity / epithelial cilium movement involved in extracellular fluid movement / cilium movement involved in cell motility / regulation of cilium beat frequency involved in ciliary motility / regulation of store-operated calcium entry / COPI-mediated anterograde transport / Aggrephagy / protein localization to organelle / intraciliary transport / 9+2 motile cilium / 転移酵素; リンを含む基を移すもの / Kinesins / acrosomal membrane / PKR-mediated signaling / Mitotic Prometaphase / EML4 and NUDC in mitotic spindle formation / Resolution of Sister Chromatid Cohesion / ciliary transition zone / cilium movement / RHO GTPases activate IQGAPs / The role of GTSE1 in G2/M progression after G2 checkpoint / calcium ion sensor activity / axoneme assembly / Recycling pathway of L1 / axonemal microtubule / left/right axis specification / cilium organization / COPI-dependent Golgi-to-ER retrograde traffic / flagellated sperm motility / RHO GTPases Activate Formins / gamma-tubulin ring complex / Separation of Sister Chromatids / Hedgehog 'off' state / Loss of Nlp from mitotic centrosomes / Recruitment of mitotic centrosome proteins and complexes / Loss of proteins required for interphase microtubule organization from the centrosome / Recruitment of NuMA to mitotic centrosomes / Anchoring of the basal body to the plasma membrane / AURKA Activation by TPX2 / Regulation of PLK1 Activity at G2/M Transition / manchette / positive regulation of cilium assembly / MHC class II antigen presentation / protein targeting to mitochondrion / UTP biosynthetic process / CTP biosynthetic process / motile cilium / positive regulation of cell motility / determination of left/right symmetry / protein targeting to membrane / GTP biosynthetic process / microtubule organizing center / intermediate filament / nucleoside diphosphate kinase activity / ciliary base / extrinsic component of membrane / receptor clustering / tubulin complex / intercellular bridge / myosin phosphatase activity / protein-serine/threonine phosphatase / regulation of neuron projection development / AMP binding / cytoplasmic microtubule / beta-tubulin binding / regulation of cell division / phosphatase activity / axoneme / phosphoprotein phosphatase activity / microtubule-based process / mitotic cytokinesis / centriolar satellite
類似検索 - 分子機能
: / Atypical dual specificity phosphatase, subfamily B / Protein of unknown function DUF4513 / Sperm-associated microtubule inner protein 10 / Tektin bundle interacting protein 1 / Coiled-coil domain-containing protein 105 / Tektin bundle interacting protein 1 / DJBP, EF-hand domain / : / EF-hand domain ...: / Atypical dual specificity phosphatase, subfamily B / Protein of unknown function DUF4513 / Sperm-associated microtubule inner protein 10 / Tektin bundle interacting protein 1 / Coiled-coil domain-containing protein 105 / Tektin bundle interacting protein 1 / DJBP, EF-hand domain / : / EF-hand domain / Sperm-associated antigen 8 / Sperm acrosome-associated protein 9 / Cilia- and flagella-associated protein 95 / NDPK7, first NDPk domain / Cilia- and flagella-associated protein 107 / Sperm acrosome-associated protein 9 / Protein CFAP95 / Cilia- and flagella-associated protein 143 / Cilia and flagella associated protein 107 / Tektin / Cilia- and flagella-associated protein 276 / : / Tektin family / Protein of unknown function (DUF3695) / Cilia- and flagella-associated protein 77 / Cilia- and flagella-associated protein 77 / Uncharacterised protein FAM166/UPF0605 / Protein Flattop / Ciliary microtubule inner protein 2B-like / Flattop / Nucleoside diphosphate kinase 7 / Meiosis-specific nuclear structural protein 1 / Piercer of microtubule wall 1/2 / Cilia- and flagella-associated protein 141 / Cilia- and flagella-associated protein 45 / NDPK7, second NDPk domain / Cilia- and flagella- associated protein 210 / CFAP53/TCHP / Trichohyalin-plectin-homology domain / Trichohyalin-plectin-homology domain / Piercer of microtubule wall 1/2 / Cilia- and flagella-associated protein 141 / RIB43A / RIB43A / DM10 domain / EF-hand domain-containing protein EFHC1/EFHC2/EFHB / : / DM10 domain / DM10 domain profile. / Domains in hypothetical proteins in Drosophila, C. elegans and mammals. Occurs singly in some nucleoside diphosphate kinases. / Enkurin domain / : / Calmodulin-binding / Enkurin domain profile. / CFA20 domain / Cilia- and flagella-associated protein 20/CFAP20DC / : / CFA20 domain / Parkin co-regulated protein / Parkin co-regulated protein / Dual specificity phosphatase, catalytic domain / Dual specificity phosphatase, catalytic domain / EF hand / Dual specificity phosphatase, catalytic domain / Nucleoside diphosphate kinase (NDPK)-like domain profile. / Dual specificity protein phosphatase domain profile. / Dual specificity protein phosphatase domain / Nucleoside diphosphate kinase / Nucleoside diphosphate kinase-like domain / Nucleoside diphosphate kinase / NDK / Nucleoside diphosphate kinase-like domain superfamily / EF-hand domain pair / Mir domain superfamily / Alpha tubulin / Tubulin-beta mRNA autoregulation signal. / Beta tubulin, autoregulation binding site / Beta tubulin / Tubulin / Tubulin, C-terminal / Tubulin C-terminal domain / Tyrosine specific protein phosphatases active site. / Tubulin, conserved site / Tubulin subunits alpha, beta, and gamma signature. / Protein-tyrosine phosphatase, active site / Tyrosine-specific protein phosphatases domain / Tyrosine specific protein phosphatases domain profile. / Tubulin/FtsZ family, C-terminal domain / Tubulin/FtsZ-like, C-terminal domain / Tubulin/FtsZ, C-terminal / Tubulin/FtsZ, 2-layer sandwich domain / Tubulin/FtsZ family, GTPase domain / Tubulin/FtsZ family, GTPase domain / Tubulin/FtsZ, GTPase domain / Protein-tyrosine phosphatase-like / Tubulin/FtsZ, GTPase domain superfamily / EF-hand domain pair / EF-hand, calcium binding motif / EF-Hand 1, calcium-binding site / EF-hand calcium-binding domain.
類似検索 - ドメイン・相同性
Cilia- and flagella-associated protein 77 / Cilia- and flagella- associated protein 210 / Tektin bundle-interacting protein 1 / Tektin-5 / Tubulin alpha-3 chain / Tubulin beta-4B chain / Tektin-4 / Sperm-associated antigen 8 / Cilia- and flagella-associated protein 107 / Piercer of microtubule wall 1 protein ...Cilia- and flagella-associated protein 77 / Cilia- and flagella- associated protein 210 / Tektin bundle-interacting protein 1 / Tektin-5 / Tubulin alpha-3 chain / Tubulin beta-4B chain / Tektin-4 / Sperm-associated antigen 8 / Cilia- and flagella-associated protein 107 / Piercer of microtubule wall 1 protein / Cilia- and flagella-associated protein 52 / Meiosis-specific nuclear structural protein 1 / EF-hand calcium-binding domain-containing protein 6 / Protein Flattop / Cilia- and flagella-associated protein 161 / Enkurin / Tektin-3 / Sperm acrosome-associated protein 9 / Cilia- and flagella-associated protein 20 / EF-hand domain-containing family member B / Tektin-2 / Cilia- and flagella-associated protein 95 / Cilia- and flagella-associated protein 53 / EF-hand domain-containing family member C2 / Ciliary microtubule inner protein 2A / Tektin-like protein 1 / RIB43A-like with coiled-coils protein 2 / Dual specificity phosphatase 21 / Cilia- and flagella-associated protein 141 / Sperm-associated microtubule inner protein 10 / EF-hand domain-containing protein 1 / Cilia- and flagella-associated protein 45 / Cilia- and flagella-associated protein 276 / Tektin-1 / Parkin coregulated gene protein homolog / Ciliary microtubule inner protein 2C / Nucleoside diphosphate kinase homolog 7 / Piercer of microtubule wall 2 protein
類似検索 - 構成要素
生物種Mus musculus (ハツカネズミ)
手法サブトモグラム平均法 / クライオ電子顕微鏡法 / 解像度: 6.5 Å
データ登録者Zhu Y / Yin GL / Tai LH / Sun F
資金援助 中国, 1件
OrganizationGrant number国
National Natural Science Foundation of China (NSFC)31925026 中国
引用ジャーナル: Cell Discov / 年: 2023
タイトル: In-cell structural insight into the stability of sperm microtubule doublet.
著者: Linhua Tai / Guoliang Yin / Xiaojun Huang / Fei Sun / Yun Zhu /
要旨: The propulsion for mammalian sperm swimming is generated by flagella beating. Microtubule doublets (DMTs) along with microtubule inner proteins (MIPs) are essential structural blocks of flagella. ...The propulsion for mammalian sperm swimming is generated by flagella beating. Microtubule doublets (DMTs) along with microtubule inner proteins (MIPs) are essential structural blocks of flagella. However, the intricate molecular architecture of intact sperm DMT remains elusive. Here, by in situ cryo-electron tomography, we solved the in-cell structure of mouse sperm DMT at 4.5-7.5 Å resolutions, and built its model with 36 kinds of MIPs in 48 nm periodicity. We identified multiple copies of Tektin5 that reinforce Tektin bundle, and multiple MIPs with different periodicities that anchor the Tektin bundle to tubulin wall. This architecture contributes to a superior stability of A-tubule than B-tubule of DMT, which was revealed by structural comparison of DMTs from the intact and deformed axonemes. Our work provides an overall molecular picture of intact sperm DMT in 48 nm periodicity that is essential to understand the molecular mechanism of sperm motility as well as the related ciliopathies.
履歴
登録2023年2月2日-
ヘッダ(付随情報) 公開2023年10月11日-
マップ公開2023年10月11日-
更新2023年12月6日-
現状2023年12月6日処理サイト: PDBj / 状態: 公開

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構造の表示

添付画像

emd_35230.png

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マップ

ファイルダウンロード / ファイル: emd_35230.map.gz / 形式: CCP4 / 大きさ: 125 MB / タイプ: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
注釈In situ structure of axonemal doublet microtubules in mouse sperm with 48-nm repeat
投影像・断面図

画像のコントロール

大きさ
明度
コントラスト
その他
軸Z (Sec.)Y (Row.)X (Col.)
1.76 Å/pix.
x 320 pix.
= 563.2 Å		1.76 Å/pix.
x 320 pix.
= 563.2 Å		1.76 Å/pix.
x 320 pix.
= 563.2 Å

表面

投影像

断面 (1/3)

断面 (1/2)

断面 (2/3)

画像は Spider により作成

ボクセルのサイズX=Y=Z: 1.76 Å
密度

ヒストグラム

ヒストグラム (対数)
表面レベル登録者による: 0.003
最小 - 最大0.0 - 0.008947917
平均 (標準偏差)0.0006520066 (±0.001116937)
対称性空間群: 1
詳細

EMDB XML:

マップ形状
Axis orderXYZ
Origin000
サイズ320320320
Spacing320320320
セルA=B=C: 563.2 Å
α=β=γ: 90.0 °

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添付データ

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試料の構成要素

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全体 : mouse sperm

全体名称: mouse sperm
要素
  • 細胞: mouse sperm
    • タンパク質・ペプチド: Meiosis-specific nuclear structural protein 1
    • タンパク質・ペプチド: Tektin-1
    • タンパク質・ペプチド: Tubulin beta-4B chain
    • タンパク質・ペプチド: Detyrosinated tubulin alpha-3 chain
    • タンパク質・ペプチド: Tektin-2
    • タンパク質・ペプチド: Nucleoside diphosphate kinase 7
    • タンパク質・ペプチド: Tektin-3
    • タンパク質・ペプチド: Tektin-4
    • タンパク質・ペプチド: EF-hand domain-containing family member B
    • タンパク質・ペプチド: Tektin bundle-interacting protein 1
    • タンパク質・ペプチド: Tektin-5
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 53
    • タンパク質・ペプチド: EF-hand domain-containing protein 1
    • タンパク質・ペプチド: EF-hand domain-containing family member C2
    • タンパク質・ペプチド: Protein FAM166A
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 95
    • タンパク質・ペプチド: Protein FAM166C
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 107
    • タンパク質・ペプチド: Dual specificity phosphatase 21
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 161
    • タンパク質・ペプチド: Coiled-coil domain-containing protein 105
    • タンパク質・ペプチド: Enkurin
    • タンパク質・ペプチド: Piercer of microtubule wall 1 protein
    • タンパク質・ペプチド: Testis-expressed protein 43
    • タンパク質・ペプチド: Piercer of microtubule wall 2 protein
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 276
    • タンパク質・ペプチド: RIB43A-like with coiled-coils protein 2
    • タンパク質・ペプチド: Protein Flattop
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 52
    • タンパク質・ペプチド: EF-hand calcium-binding domain-containing protein 6
    • タンパク質・ペプチド: Cilia and flagella-associated protein 77
    • タンパク質・ペプチド: Sperm-associated antigen 8
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 45
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 20
    • タンパク質・ペプチド: Parkin coregulated gene protein homolog
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 210
    • タンパク質・ペプチド: Sperm acrosome-associated protein 9
    • タンパク質・ペプチド: Cilia- and flagella-associated protein 141
  • リガンド: GUANOSINE-5'-TRIPHOSPHATE

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超分子 #1: mouse sperm

超分子名称: mouse sperm / タイプ: cell / ID: 1 / 親要素: 0 / 含まれる分子: #1-#38
由来(天然)生物種: Mus musculus (ハツカネズミ)

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分子 #1: Meiosis-specific nuclear structural protein 1

分子名称: Meiosis-specific nuclear structural protein 1 / タイプ: protein_or_peptide / ID: 1 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 60.353012 KDa
配列文字列: MATKKRALSF SEKHQKLVDE KFRKSLNIQV MNKLERQAKN QVVQNENDEK VERQRFLRVL QNEQFELDME EAIQKAEANK MLRDRQLEQ EERLANELAR LKHESLKDKK MRQQVRENSI ELRELEQKLK AAYMNKERAA QIVEKDAMKY EQMKRDAEIE R IMMEEHDR ...文字列:
MATKKRALSF SEKHQKLVDE KFRKSLNIQV MNKLERQAKN QVVQNENDEK VERQRFLRVL QNEQFELDME EAIQKAEANK MLRDRQLEQ EERLANELAR LKHESLKDKK MRQQVRENSI ELRELEQKLK AAYMNKERAA QIVEKDAMKY EQMKRDAEIE R IMMEEHDR LLKEESAKQE RRNKERAQYY LDLEKQLEDQ ERRKQEAYEQ LLKEKLMIDE IVRKIYEEDQ VERQQKLEKK NA IQKYIEE FQRAQDFWRQ KKREEMEEEN RKIIEFANIQ EQREGERMAR VHEIEEKRVQ RQNLLMKQLE ETLRQRDDLE QVR QELYQE EQAEIIKLKV KEEAELRLRR QREMKQDFED QMALKELILQ AAKEEEETFK KAMLAKFAED DRIELMNAQK QRMK QLEHK RAVEKLIEER RSQFLADKQR ELEELQLQQR RQGCINEIIE EERLRLLKEH AAKLLGYLPK GVFKREDDVD MLGEE FRKA YQKRDGV

UniProtKB: Meiosis-specific nuclear structural protein 1

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分子 #2: Tektin-1

分子名称: Tektin-1 / タイプ: protein_or_peptide / ID: 2 / コピー数: 4 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 48.713035 KDa
配列文字列: MAKLLQSPPR FLPEEWYIAN KSQYHRAEAQ RSQSERLVAE SQRLVEEIEK TTRKSQSDVN KKLEQRLEEV RFWKKELDDK LEQLVNQTD DLLTYKTRLE RSLESYKEPL HITEKCLEYR EKRVGIDLVH DVVEQELQKE ADIIHGVMNL LIRTLEESTE Q IRLNRSAK ...文字列:
MAKLLQSPPR FLPEEWYIAN KSQYHRAEAQ RSQSERLVAE SQRLVEEIEK TTRKSQSDVN KKLEQRLEEV RFWKKELDDK LEQLVNQTD DLLTYKTRLE RSLESYKEPL HITEKCLEYR EKRVGIDLVH DVVEQELQKE ADIIHGVMNL LIRTLEESTE Q IRLNRSAK YNLEKDLRDK FTAITIDDVC FSLNNNSPNI NFSEKVVRIE PNSVSLEDWL DFSNANVEKA DKQLNNSTAL KT LVDQILS QTANDLRRQC EVVDEAFING LKETKDARNK LADHLAKVME EIASQEKNIM ALENAITQQE GPAKVAHTRL ETR THRPNV ELCRDIAQYR LIKEIQEINH NVARLKETLA QAQTQLKALY RRQLALQEEI QVKENTIYID QVLCMEMRKS IPPR DGDDH GAWEGGIRAE AIC

UniProtKB: Tektin-1

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分子 #3: Tubulin beta-4B chain

分子名称: Tubulin beta-4B chain / タイプ: protein_or_peptide / ID: 3 / コピー数: 139 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 47.897918 KDa
配列文字列: MREIVHLQAG QCGNQIGAKF WEVISDEHGI DPTGTYHGDS DLQLERINVY YNEATGGKYV PRAVLVDLEP GTMDSVRSGP FGQIFRPDN FVFGQSGAGN NWAKGHYTEG AELVDSVLDV VRKEAESCDC LQGFQLTHSL GGGTGSGMGT LLISKIREEY P DRIMNTFS ...文字列:
MREIVHLQAG QCGNQIGAKF WEVISDEHGI DPTGTYHGDS DLQLERINVY YNEATGGKYV PRAVLVDLEP GTMDSVRSGP FGQIFRPDN FVFGQSGAGN NWAKGHYTEG AELVDSVLDV VRKEAESCDC LQGFQLTHSL GGGTGSGMGT LLISKIREEY P DRIMNTFS VVPSPKVSDT VVEPYNATLS VHQLVENTDE TYCIDNEALY DICFRTLKLT TPTYGDLNHL VSATMSGVTT CL RFPGQLN ADLRKLAVNM VPFPRLHFFM PGFAPLTSRG SQQYRALTVP ELTQQMFDAK NMMAACDPRH GRYLTVAAVF RGR MSMKEV DEQMLNVQNK NSSYFVEWIP NNVKTAVCDI PPRGLKMSAT FIGNSTAIQE LFKRISEQFT AMFRRKAFLH WYTG EGMDE MEFTEAESNM NDLVSEYQQY QD

UniProtKB: Tubulin beta-4B chain

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分子 #4: Detyrosinated tubulin alpha-3 chain

分子名称: Detyrosinated tubulin alpha-3 chain / タイプ: protein_or_peptide / ID: 4 / コピー数: 140 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 48.68909 KDa
配列文字列: MRECISIHVG QAGVQIGNAC WELYCLEHGI QPDGQMPSDK TIGGGDDSFN TFFSETGAGK HVPRAVFVDL EPTVVDEVRT GTYRQLFHP EQLITGKEDA ANNYARGHYT IGKEIVDLVL DRIRKLADLC TGLQGFLIFH SFGGGTGSGF ASLLMERLSV D YGKKSKLE ...文字列:
MRECISIHVG QAGVQIGNAC WELYCLEHGI QPDGQMPSDK TIGGGDDSFN TFFSETGAGK HVPRAVFVDL EPTVVDEVRT GTYRQLFHP EQLITGKEDA ANNYARGHYT IGKEIVDLVL DRIRKLADLC TGLQGFLIFH SFGGGTGSGF ASLLMERLSV D YGKKSKLE FAIYPAPQVS TAVVEPYNSI LTTHTTLEHS DCAFMVDNEA IYDICRRNLD IERPTYTNLN RLIGQIVSSI TA SLRFDGA LNVDLTEFQT NLVPYPRIHF PLATYAPVIS AEKAYHEQLS VAEITNACFE PANQMVKCDP RHGKYMACCM LYR GDVVPK DVNAAIATIK TKRTIQFVDW CPTGFKVGIN YQPPTVVPGG DLAKVQRAVC MLSNTTAIAE AWARLDHKFD LMYA KRAFV HWYVGEGMEE GEFSEAREDL AALEKDYEEV GVD

UniProtKB: Tubulin alpha-3 chain

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分子 #5: Tektin-2

分子名称: Tektin-2 / タイプ: protein_or_peptide / ID: 5 / コピー数: 9 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 50.385066 KDa
配列文字列: MATLSFKPSE RYRLSDWRTN SYLLSTNAER QRDASHQIRQ EARILRNETN NQIVWDEHDN RTRLAERIDT VNRWKETLDK CLTDLDAEI DSLAQAKESA EQNLQAKNLP LDVAIECLTL RESRRDIDVV RDPVEEELLK EVEVIEATKK VLQEKISQAF Q HLCLLQEI ...文字列:
MATLSFKPSE RYRLSDWRTN SYLLSTNAER QRDASHQIRQ EARILRNETN NQIVWDEHDN RTRLAERIDT VNRWKETLDK CLTDLDAEI DSLAQAKESA EQNLQAKNLP LDVAIECLTL RESRRDIDVV RDPVEEELLK EVEVIEATKK VLQEKISQAF Q HLCLLQEI RQQLNSDHRD KMETLEIDRG CLSLNLTSPN ISLKVNPTRI PKDSTTLQQW DEFTRFNKNR AEAEMKASIE LR EAIALAI AQTNNELDAQ RVATEFTFRK RLREMESFYS ELKWQEKNTL EEIAELQGDI RRLEEDLRRK MMNLKLAHTR LES RTYRSN VELCRDQTQY GLIDEVHQLE ATINTMKQKL AQTQNALDAL FKHLARIQAD IACKTNTLLL DTKCMDTRRK LTVP AEKFV PQVDTFTRTT NRTLSPLKIC QLELT

UniProtKB: Tektin-2

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分子 #6: Nucleoside diphosphate kinase 7

分子名称: Nucleoside diphosphate kinase 7 / タイプ: protein_or_peptide / ID: 6 / コピー数: 2 / 光学異性体: LEVO / EC番号: nucleoside-diphosphate kinase
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 44.489828 KDa
配列文字列: MRACQQGRSS SLVSPYMAPK NQSERFAFIA EWYDPNASLL RRYELLFYPV DGSVEMHDVK NRRTFLKRTK YEDLRLEDLF IGNKVNVFS RQLVLIDYGD QYTARQLGSR KEKTLALIKP DAVSKAGEII EMINKSGFTI TKLRMMTLTR KEAADFHVDH H SRPFYNEL ...文字列:
MRACQQGRSS SLVSPYMAPK NQSERFAFIA EWYDPNASLL RRYELLFYPV DGSVEMHDVK NRRTFLKRTK YEDLRLEDLF IGNKVNVFS RQLVLIDYGD QYTARQLGSR KEKTLALIKP DAVSKAGEII EMINKSGFTI TKLRMMTLTR KEAADFHVDH H SRPFYNEL IQFITSGPVI AMEILRDDAI CEWKRLLGPA NSGLSRTDAP GSIRALFGTD GVRNAAHGPD TFASAAREME LF FPSSGGC GPANTAKFTN CTCCIIKPHA ISEGMLGKNL IAIRDACFGM SAIQMFNLDR ANVEEFYEVY KGVVSEYNDM VTE LCSGPC VAIEIQQSNP TKTFREFCGP ADPEIARHLR PETLRAIFGK TKVQNAVHCT DLPEDGLLEV QYFFKILDN

UniProtKB: Nucleoside diphosphate kinase homolog 7

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分子 #7: Tektin-3

分子名称: Tektin-3 / タイプ: protein_or_peptide / ID: 7 / コピー数: 13 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 56.754777 KDa
配列文字列: MELLGSTLTA TYAHPPPASA SFLPAIGTIT SSYKDRFPHR NLTHSLSLPW RPNTYYKTAY NYPTLAPYSS RSQRVCESTM LPFVSNRTT FFTRYTPDDW YRSNLVSFQE SNSSRHNSER LRVDTSRLIQ DKYQQIRKTQ AHSTQNLGER VNDLAFWKSE I THELDEMI ...文字列:
MELLGSTLTA TYAHPPPASA SFLPAIGTIT SSYKDRFPHR NLTHSLSLPW RPNTYYKTAY NYPTLAPYSS RSQRVCESTM LPFVSNRTT FFTRYTPDDW YRSNLVSFQE SNSSRHNSER LRVDTSRLIQ DKYQQIRKTQ AHSTQNLGER VNDLAFWKSE I THELDEMI GETNALTDIK RRLERGLIET EGPLQVSREC LFHREKRMGI DLVHDEAEKE LLAEVDTILC CQERMRQHLD KA NAQLASD RSAQHELEKD LSDKQAALRI DDKCQHLRNT SEGVSYFRGV ERVDATVSVP ETWAKFTDDN VLRSQSERAA SAK LREETE NLLIVTANEM WNQFNKVNLA FTNRIAETVD AKNKIHTHLT KTLQEIFQIE MTIESIKKAI KEKSAFLKVA QTRL DERTR RPNVELCRDM AQLRLVNEVY EVDETIQTLQ QRLRDSEDTL QSLAHTKATL EHDLAVKANT LYIDQEKCMS MRNSY PSTL RLVGYC

UniProtKB: Tektin-3

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分子 #8: Tektin-4

分子名称: Tektin-4 / タイプ: protein_or_peptide / ID: 8 / コピー数: 10 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 52.121449 KDa
配列文字列: MAQTGVLLTK EPAPQSIDVC ELPRKEYEVA CNTGAYTSSG LATAGFRTAK YLRDEWFQNS YARYHQAFAD RDYSERQRHE SGQLVAETG ALAQRTQLDS TRKVGERLED MHCWKSELQR EIDELSSETD LMMAQKLRLQ RALDATSVPY SIATDNLQCR E RRQHPDLV ...文字列:
MAQTGVLLTK EPAPQSIDVC ELPRKEYEVA CNTGAYTSSG LATAGFRTAK YLRDEWFQNS YARYHQAFAD RDYSERQRHE SGQLVAETG ALAQRTQLDS TRKVGERLED MHCWKSELQR EIDELSSETD LMMAQKLRLQ RALDATSVPY SIATDNLQCR E RRQHPDLV RDYVEVELLK ETELIRNIQE LLKRTIGQAV DQIRLNREHK ESCEMNWSDK VEVYNIDDTC SRYTNESTQV QF YPHSSKF EESASTPETW AKFNHDNLLR AERERLASVN LRKLIDCILR DTAEDLRLQC DAVNSAFSSR CQELDDSLQK LQY HLRKTL TEITDQEHQI AALKQAIKDK EAPLRVAQTR LYQRSHRPNV ELCRDNAQFR LLSEVEELNM SLRALKEKLQ DAEQ ALRNL EDSRMSLEKD IAVKTNSLFI DRQKCMTHRN RYPSVLQLAG YQ

UniProtKB: Tektin-4

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分子 #9: EF-hand domain-containing family member B

分子名称: EF-hand domain-containing family member B / タイプ: protein_or_peptide / ID: 9 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 95.891961 KDa
配列文字列: MCSFVRVGSP KPLQTSASPL EMSSLRRTRA PEISELGLTP EQKDDIRDRV LRGSKSPTEL GFDLRLEQDR KWRERMGSSE AKSPPCHAL GVGLERHTIS GTPTEMGNLG LHKGSAFQGS KPLGVLPGRV GPENKGLPPR LRYGGTLHPP FSTVHASPLA A ESRRRPLA ...文字列:
MCSFVRVGSP KPLQTSASPL EMSSLRRTRA PEISELGLTP EQKDDIRDRV LRGSKSPTEL GFDLRLEQDR KWRERMGSSE AKSPPCHAL GVGLERHTIS GTPTEMGNLG LHKGSAFQGS KPLGVLPGRV GPENKGLPPR LRYGGTLHPP FSTVHASPLA A ESRRRPLA WGSAWTDAVV EKQPVVGLEL RKEPEKEPTC VVMNPYPEMP PKEVDIGLPQ TQESDEAKNT EPLIGLVREP SE CPFAQQP EEKKEPGSTE PGVEPPGNIR PIYSGKFFDR VPCWPSAGKV KPVGYRVATC LTEKLPRLMT PPEAKKYFNF RYP PAGAER VFYGRANDPQ IAPYLTHGLR SKISIPMGSL INPQPITTFQ QKIKDKKESI YFSHQRAPLG KSHDQTPGLP KGMD VINTT LGTPTIRELS VRDTVNPSKS FEDVLKEGQE GHDLYTVSHN DYFAGEAKNR KYNPASFHRF NLYGIPTPHF NDGRT MAKA LHWLHELQME RGAKIVSKRV DDFKEKFQHK LGKVLDPIAE TMNVPPGHTF GSCLHPEEYG AGDLIHYRSP DEYLRG KDH QRAVVAAARH HLKKFNHQNF DTLQVAFRHY DKKGDGVIDR AELHEACVQA NLHLDKMLLD HLFDYCDVDQ DGLINYL EF ANFLNWKDRI PLKEHEKRVV VKGKKPDCEN VTDTSMGEAE PSLLINPEDI VPKEPGSSEE TLRTIQRPGD KVSHQYKT T SSEINAVVGA VPSMCHPIFG VPTIRSDISA PRIRRVSDMN NYGDEGNAYS LLHPSIFSQK GVFERDFFKT RSKEEISDI LTNIGVKLSK EEFENVWNLA SKKHQRGEVC VETIRNVLDE LLHADLVKCK TAM

UniProtKB: EF-hand domain-containing family member B

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分子 #10: Tektin bundle-interacting protein 1

分子名称: Tektin bundle-interacting protein 1 / タイプ: protein_or_peptide / ID: 10 / コピー数: 4 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 23.987262 KDa
配列文字列: MENVRREATR PSVPSGTLEL YFPDHLYRND YVSLEGPRWA PAIKQAVRWK FTPMGRDAAG QVWFTGLTNS EPGDAWYKLP RALDTPYRE AHTRWHGCFQ SRQRGLPPAY TQHLREMAFW DPAITAQYLN SGPRWGCMQW RDRQIRGKEF VVTRNQFGAK L PWRSDYVP ...文字列:
MENVRREATR PSVPSGTLEL YFPDHLYRND YVSLEGPRWA PAIKQAVRWK FTPMGRDAAG QVWFTGLTNS EPGDAWYKLP RALDTPYRE AHTRWHGCFQ SRQRGLPPAY TQHLREMAFW DPAITAQYLN SGPRWGCMQW RDRQIRGKEF VVTRNQFGAK L PWRSDYVP LLSLPQRPRF TAQDFRQRGL QRPCPAIGQP PPAFTPAL

UniProtKB: Tektin bundle-interacting protein 1

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分子 #11: Tektin-5

分子名称: Tektin-5 / タイプ: protein_or_peptide / ID: 11 / コピー数: 22 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 62.817535 KDa
配列文字列: MEFLGTTQTA SFCGPKKGCG LQALPPAGQE PVVQECYQPF HLPGYRYLNA WRPSVFHKIA TSQTIPEECS GIRRPPTILP SLRSALFCR YTPRDWDRSN DLQIRNAEAS RLWASRLTGD SLRIMQDKDQ LIHQMQEGTS RNLGQRLSDL GFWKSELCYE L DRLLTENS ...文字列:
MEFLGTTQTA SFCGPKKGCG LQALPPAGQE PVVQECYQPF HLPGYRYLNA WRPSVFHKIA TSQTIPEECS GIRRPPTILP SLRSALFCR YTPRDWDRSN DLQIRNAEAS RLWASRLTGD SLRIMQDKDQ LIHQMQEGTS RNLGQRLSDL GFWKSELCYE L DRLLTENS SMDTLKRRLE CAAEEVNCPL QVALECLYNR EKRIGIDLVH DNVEKNLIRE VDLLKCCQDQ MRKLAKRIDF QI RDNRDAQ HSLERDIEDK SSAQYIDENC FNLRSTSDSI SFFHGVEKFD GTVSIPETWA KFSNDNIRHA QNMRANSIRL REE AEHLFE TLSDQMWKQF TNTNLAFNAR ISEETDVKNK LQTQLAKILQ EIFQAENTIM LLERAIVAKE YPLKMAQTML ACRT RRPNV ELCRDVPQFR LVNEVFTIDD TLQTLKLRLR ETQDTLQLLV MTKSRLEHEL AIKANTLCID KDKCMSMRKS FPSTP RLTG YTCSAIGSGP YANHAPRISS GPCSGSALCK GPASCGGGAS CGGGASCGGH APCGSALCSH SVSRSGPGFA PVC

UniProtKB: Tektin-5

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分子 #12: Cilia- and flagella-associated protein 53

分子名称: Cilia- and flagella-associated protein 53 / タイプ: protein_or_peptide / ID: 12 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 62.036609 KDa
配列文字列: MYSQQFGTVP REFKGPTPKA VIIRAKPPKA QRAEQHLKRI QRSYHKYHTT LASIKSNEEN RLKCDWIQRN NHKTFDSLVQ ARVQDAMQG FVINTEERRN KLRELLASEE NEYFSEMQLK GETIEEKKDK MRERTKLLRE KKEKERQEFV AEKLDQQFRE R CEELRTKL ...文字列:
MYSQQFGTVP REFKGPTPKA VIIRAKPPKA QRAEQHLKRI QRSYHKYHTT LASIKSNEEN RLKCDWIQRN NHKTFDSLVQ ARVQDAMQG FVINTEERRN KLRELLASEE NEYFSEMQLK GETIEEKKDK MRERTKLLRE KKEKERQEFV AEKLDQQFRE R CEELRTKL ASIHEKKVVE ERNAQIEFNK ELKRQKLVEE HLFARLWEED RLAKERREAQ EEKRQRELVQ NTRLGLDAQV TS IQAQRQG ARRMKEEEAR ILEQNKAQIK REDEQEKLQK QKRRQETRSS LKKAVQDKIE SMQREYREDL DLNMKLVGRA LQD LQDEAD KKKQKREEMG REQKIYNDYL MQRREEEKAQ EKELNRLLED IKAKKLAEKD RELALQRAAR KQLMNEVMNT RKLQ VQERL QRKLREQEEL ALHEQRISES LKVLHQEDME DFARRCALAE EYRNQLQMQI AHQQQAREAE KEEERQEFEA GLAAN KACL DKIQRILSEN QALSQNVHPM RRGYPDKPPL

UniProtKB: Cilia- and flagella-associated protein 53

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分子 #13: EF-hand domain-containing protein 1

分子名称: EF-hand domain-containing protein 1 / タイプ: protein_or_peptide / ID: 13 / コピー数: 3 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 75.235422 KDa
配列文字列: MGTNPVHGLP FLPGSSFTDS TKTAFHRSQT LNYRNGYAVV RRPTMGIGGD RLHYNQLSQA ELDELANKAP ILTYGPLKQA PLAEFVPAH VAFDKKVLKF SAYFQEDVPI SMEEHYRIRH VNIYYYLEDD SMSVIEPVVE NSGIPQGKLI KRQRFTKNDM G DHYHWKDL ...文字列:
MGTNPVHGLP FLPGSSFTDS TKTAFHRSQT LNYRNGYAVV RRPTMGIGGD RLHYNQLSQA ELDELANKAP ILTYGPLKQA PLAEFVPAH VAFDKKVLKF SAYFQEDVPI SMEEHYRIRH VNIYYYLEDD SMSVIEPVVE NSGIPQGKLI KRQRFTKNDM G DHYHWKDL NRGINLTVYG KTFRIVDCDR FTQDFLESQG IELNPSEKIP LDPYTQLRKE PVRKYVTPSD FDQLKQFLTF DK QVLRFYA IWDDTDSLFG ECRHYIIHYY LMDDTVEIRE VHERNNGRDP FPLLMNRQRM PKVLVENAKN FPKCVLEISD QEV LEWYTA KDFIVGKPLT ILGRTFFIYD CDPFTRQFYK DKFGMPDLPP VDVTKKEPPP VKQELPPYNG YGLIEDSAQN CFAL IPKAP RKDVVKMLMN DNKVLRYLAA LESPIPEDKD RRFVFSYFLA TDMISIFEPP VRNSGIIGGK FLGRTKVVKS FSPVD NPIY YSPSDFFIGA VIEVFGHRFV ILDTDEYVLK YMESNASQYS PEALASIQNR IQKPELPAPE LESKQATGEP MVQGTE ESK VQDLDALIDQ IHMHLKYNSY KENLRETFQM YDKDESGYVD RETFFKICET LNVPVDDSLI KELIRLCTHG EGRINYY NF VRAFSN

UniProtKB: EF-hand domain-containing protein 1

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分子 #14: EF-hand domain-containing family member C2

分子名称: EF-hand domain-containing family member C2 / タイプ: protein_or_peptide / ID: 14 / コピー数: 3 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 87.758023 KDa
配列文字列: MALPFLPGNS FNRNIGKERF HKSQHWGFCN NVRMLVSENK PGVGGDLLYG QKIKPKHSVF PKGDGTDAPS WVAFDKQVLS FDAYLEDEI SDKRQEIFRI RYYKIYFYLE DDTIQVNEPE VINSGLPQGT SIRRQRIPYP PPNDDQFYTV YDFNINISVV F YGRTFKIY ...文字列:
MALPFLPGNS FNRNIGKERF HKSQHWGFCN NVRMLVSENK PGVGGDLLYG QKIKPKHSVF PKGDGTDAPS WVAFDKQVLS FDAYLEDEI SDKRQEIFRI RYYKIYFYLE DDTIQVNEPE VINSGLPQGT SIRRQRIPYP PPNDDQFYTV YDFNINISVV F YGRTFKIY DCDPFTKNFL KKIGIKLNPP GQCPLDPYMK MRRETLEFVD PFRPYQSFDT LKRFIQYDGK VLRFFCLWDD ST SLFGDRR EFVLHYFLCD GTVEIREVLP SNSGRDAMSS FLRRGKLPKY GPPGIYQPGQ ITDRAVLNVY GGLSEWRADG YLL DKYQLG KVEQDFYTDQ DLSIGATINV WGRKVLLCDC DEFTKTYYRT KYGVDNFTPI SCKPPHLPKI ERKYPPYTGF GSEE DSFRS CVGLKPTPHR KNFKKFMELD SFGNISNILR YFGKLITHKC ADVDRIFVIA FYLSDDTISV FEPIENNSGN AGGMF LKRS RVKKPGQEVF KSEFSEYIKA EELYIGATVN INGYLFILLN ADEYTLNYME NNTDKFPYSN FELAIQKLKQ EKSKSR EIT QVFAAADYNH TKVVPYNTFR DILMSITMGK LIDQELITIA RHYRVPEIMD PDLAYLIARA HEKFKKNIFE NFDMFIY NC VYEDREKKGV LPTKDIRRMC KSSRLPLDDD FLDCLLSRFE DKDHQINYEI FFSVLNWRMN PTPDLQAPPY LKEKCEDV W VGMPSPIPVK YVRYLDFLID VYGLEDNML

UniProtKB: EF-hand domain-containing family member C2

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分子 #15: Protein FAM166A

分子名称: Protein FAM166A / タイプ: protein_or_peptide / ID: 15 / コピー数: 6 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 36.659566 KDa
配列文字列: MTATQKHNLF TPEPHYIPGY AGFYPQLRYQ VGNTYGRTTA QLLTDPSVQK SPCSVLSPMT KPKFIEDFSK SKPPWIPCRD LREPYIPHY TSLKPYKNFE ILGQLPRQDV DTQGPPQVEN RQGPLTAGFM PYPPYPACPP GRKGEARDLG HPGLLLAYGE E AWKDAAPL ...文字列:
MTATQKHNLF TPEPHYIPGY AGFYPQLRYQ VGNTYGRTTA QLLTDPSVQK SPCSVLSPMT KPKFIEDFSK SKPPWIPCRD LREPYIPHY TSLKPYKNFE ILGQLPRQDV DTQGPPQVEN RQGPLTAGFM PYPPYPACPP GRKGEARDLG HPGLLLAYGE E AWKDAAPL QDTPGKNNQL YHCRRDEYLP PHPPQETLDV GRFQRLPQLD HPNLIQRKAI SGYAGFVPRF AWVMGMNYRD GV TQAMDDF DKNQFVFRHP VCALGERLPR THWPNTTIYR SQGLIPFYMG FIPSMQDNYA LTFGNSTRRA YQKELDRRSH TL

UniProtKB: Ciliary microtubule inner protein 2A

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分子 #16: Cilia- and flagella-associated protein 95

分子名称: Cilia- and flagella-associated protein 95 / タイプ: protein_or_peptide / ID: 16 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 26.633035 KDa
配列文字列: MGTFDSQCHE CFESKERWYE IGPTDLLERK GSLTLRSHHK KYSEPVLVYS WHRNREAFPK DYDIESLETV KNLCMSTYKR FGSDSPRWM SEAREQMAQV LVNKDLVEKK KTGLLDEETL CPGILERDPE LPPTGFRDVP MESPPDPRKP CFSTTYSEDF T PQYEYPPP ...文字列:
MGTFDSQCHE CFESKERWYE IGPTDLLERK GSLTLRSHHK KYSEPVLVYS WHRNREAFPK DYDIESLETV KNLCMSTYKR FGSDSPRWM SEAREQMAQV LVNKDLVEKK KTGLLDEETL CPGILERDPE LPPTGFRDVP MESPPDPRKP CFSTTYSEDF T PQYEYPPP ACPRREEYSI VHRKCRSQFT DLNGSKRLGI NTWHDESGIY ANSEAKQKLY ALARNPIVPF

UniProtKB: Cilia- and flagella-associated protein 95

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分子 #17: Protein FAM166C

分子名称: Protein FAM166C / タイプ: protein_or_peptide / ID: 17 / コピー数: 3 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 23.097957 KDa
配列文字列: MAFRSAGTLM TEFNAAFVPP ALMPGYKGHV PGVASSFGSS YGNTTFKYFQ DLRNTGLEKS YALLSGGCFP TIFSPNSPLV LTDNSQNWD RWLHQPTYSR SNQDNGRTTE LTNFYKTVQQ QRKYYQDKTG ILSRVPYFVL PVKEPDRYPL PTDLPPLSEK S KWNLLRLS ...文字列:
MAFRSAGTLM TEFNAAFVPP ALMPGYKGHV PGVASSFGSS YGNTTFKYFQ DLRNTGLEKS YALLSGGCFP TIFSPNSPLV LTDNSQNWD RWLHQPTYSR SNQDNGRTTE LTNFYKTVQQ QRKYYQDKTG ILSRVPYFVL PVKEPDRYPL PTDLPPLSEK S KWNLLRLS PDYKRTYQTF PSGKRVSSQE RQRRDLYFEF RA

UniProtKB: Ciliary microtubule inner protein 2C

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分子 #18: Cilia- and flagella-associated protein 107

分子名称: Cilia- and flagella-associated protein 107 / タイプ: protein_or_peptide / ID: 18 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 23.06251 KDa
配列文字列: MAMLSTSVVP EAFSTPGWQI EKKYSTKVLL GNWVEERGKF TKAIDHTPQC IYRKEYVPMP DHRPDFVSRW YSKSKMEGLP YKHLITHHQ EPSHRYLIST YDDHYNRHNY NPGLPALRTW NGQKLLWLPE KSDFPLVAPP TNYGLLEQLQ QKWLASKTSL K ESIYTTSY ...文字列:
MAMLSTSVVP EAFSTPGWQI EKKYSTKVLL GNWVEERGKF TKAIDHTPQC IYRKEYVPMP DHRPDFVSRW YSKSKMEGLP YKHLITHHQ EPSHRYLIST YDDHYNRHNY NPGLPALRTW NGQKLLWLPE KSDFPLVAPP TNYGLLEQLQ QKWLASKTSL K ESIYTTSY PRLPVCAMSR REHAIPVPHP RLQPIPRF

UniProtKB: Cilia- and flagella-associated protein 107

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分子 #19: Dual specificity phosphatase 21

分子名称: Dual specificity phosphatase 21 / タイプ: protein_or_peptide / ID: 19 / コピー数: 3 / 光学異性体: LEVO / EC番号: protein-serine/threonine phosphatase
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 21.527574 KDa
配列文字列: MTTASCIFPS QATQQDNIYG LSQITASLFI SNSAVANDKL TLSNNHITTI INVSAEVVNT FFEDIQYVQV PVSDAPNSYL YDFFDPIAD HIHGVEMRNG RTLLHCAAGV SRSATLCLAY LMKYHNMTLL DAHTWTKTCR PIIRPNNGFW EQLIHYEFKL F SRNTVRMI ...文字列:
MTTASCIFPS QATQQDNIYG LSQITASLFI SNSAVANDKL TLSNNHITTI INVSAEVVNT FFEDIQYVQV PVSDAPNSYL YDFFDPIAD HIHGVEMRNG RTLLHCAAGV SRSATLCLAY LMKYHNMTLL DAHTWTKTCR PIIRPNNGFW EQLIHYEFKL F SRNTVRMI YSPIGLIPNI YEKEAYLMEL M

UniProtKB: Dual specificity phosphatase 21

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分子 #20: Cilia- and flagella-associated protein 161

分子名称: Cilia- and flagella-associated protein 161 / タイプ: protein_or_peptide / ID: 20 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 34.433383 KDa
配列文字列: MAQNVYGPGV RMGNWNEDVY LEEERMRHFL EKREKGELLI QRNRRVKKNI LRPMQLSVSE DGYVHYGDKV IIVNPDQVLG EEAGKFMRG DLSLCMSPDE VKAQLSDDLE IPCGVSAVQT IAPMGRNTFT ILSDGANSCE MGQVVVYGQN FCLGIAAGLE G KMLYLTSD ...文字列:
MAQNVYGPGV RMGNWNEDVY LEEERMRHFL EKREKGELLI QRNRRVKKNI LRPMQLSVSE DGYVHYGDKV IIVNPDQVLG EEAGKFMRG DLSLCMSPDE VKAQLSDDLE IPCGVSAVQT IAPMGRNTFT ILSDGANSCE MGQVVVYGQN FCLGIAAGLE G KMLYLTSD HRTLLKSSLK SGLQEVTLTD EVTHLNCWQA AFLDPQLRLE YEGFPVRANE KIVIYHRHTN RALAVHRNLF LR TYFGKEM EVVAHTYLDS HKVEKPKNQW MLVTGNPRNK SNTMLDISKP ITEDTRALEQ AMGINT

UniProtKB: Cilia- and flagella-associated protein 161

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分子 #21: Coiled-coil domain-containing protein 105

分子名称: Coiled-coil domain-containing protein 105 / タイプ: protein_or_peptide / ID: 21 / コピー数: 5 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 57.406484 KDa
配列文字列: MPVLLPSTDP GQDSRVGAPE WRQAAKATSR KAHLLTDRCG QEAVTMWQPK DSVLDPNVAH HLGRAAYMEP WRFRVEMLKG GGTLEKPPP GEGVTLWKGK MKPPAWYARL PLPMHRDARA QQTAEVVHAH ARGARLTAAR LGRAQHQING QLRLLLRQRE A TDRRLSEV ...文字列:
MPVLLPSTDP GQDSRVGAPE WRQAAKATSR KAHLLTDRCG QEAVTMWQPK DSVLDPNVAH HLGRAAYMEP WRFRVEMLKG GGTLEKPPP GEGVTLWKGK MKPPAWYARL PLPMHRDARA QQTAEVVHAH ARGARLTAAR LGRAQHQING QLRLLLRQRE A TDRRLSEV RKGLLINQQS VKLRGYRPKC EKIPDKADSL LVWEKKELKS MKRKMEKDME ISEDLLKALA SCRDTLDFYC QE RLQAVEL MNQPLDKVLE QAGRHSWVDI TRPPTPRTQG LKTPPPDPIG TYTPACAKAL FEAKRLLMES KDILTEMAKN EVD IQNQQQ EISNRVCSSL AQKMRETLEL KERMTMTLGL MRGTIHRCMK FNQEMYVTRG IIKGPLLKRN LEAREKLNRP LVRM YQRHV GTQLPEATRL AQGTDLLTRH NLHMEKNLKE LRTTHDNLAW GLNCKKIGHD VDYDVVRLRL RQRHPHVCYE QAQRL VNDW DPPTPARSQT NTASK

UniProtKB: Tektin-like protein 1

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分子 #22: Enkurin

分子名称: Enkurin / タイプ: protein_or_peptide / ID: 22 / コピー数: 4 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 29.587521 KDa
配列文字列: MDSPCTSESI YNLIPSDLKE PPQHPRYTSL FRATIKNDMK KFKTAMKTMG PAKVEIPSPK DFLKKHSKEK TLPPKKKFNR CSPKKPAVP LRTDHPVMGI QSGKNFINTN AADVIMGVAK KPKPIYVDKR TGDKHDLETS GLFPKYINKK DYGITPEYIC K RNEDVKKA ...文字列:
MDSPCTSESI YNLIPSDLKE PPQHPRYTSL FRATIKNDMK KFKTAMKTMG PAKVEIPSPK DFLKKHSKEK TLPPKKKFNR CSPKKPAVP LRTDHPVMGI QSGKNFINTN AADVIMGVAK KPKPIYVDKR TGDKHDLETS GLFPKYINKK DYGITPEYIC K RNEDVKKA QEEYDNYIQE NLKKAAMKRL SDEEREAVLQ GLKKNWEEVH KEFQSLSVFI DSVPKKIRKQ KLEKEMKQLE HD ISVIEKH KIIYIANK

UniProtKB: Enkurin

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分子 #23: Piercer of microtubule wall 1 protein

分子名称: Piercer of microtubule wall 1 protein / タイプ: protein_or_peptide / ID: 23 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 18.862852 KDa
配列文字列:
MSEEKPQQSA EEPEPGEPKA KPAPEEPEPG EPKAKPAPEE PEPGEPKAKP APEKTSDYYR ISEKLPVRFN NPGWFHGYGT KEAVSMYRT SNQTYGSRAP TVHEMPKVFY PSSNKFSRQH AAFGMFQSHN INVTLEKSLV TGPDNHITHY DRLNFHPSYN V NRPSICD

UniProtKB: Piercer of microtubule wall 1 protein

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分子 #24: Testis-expressed protein 43

分子名称: Testis-expressed protein 43 / タイプ: protein_or_peptide / ID: 24 / コピー数: 3 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 16.305608 KDa
配列文字列:
MASEKDDGPA LPKLDDDNQT AENTCKPAEE QPQQLRWDDI HLPRFSLKQG MIPTRYVMPW KENMKFRNVN LQQAEACGIY AGPLEDSLF WGYSERLCHG EDRKAVLKKG LPEIKITDMP LHSPLSRYQS TVISHGFRRR LI

UniProtKB: Sperm-associated microtubule inner protein 10

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分子 #25: Piercer of microtubule wall 2 protein

分子名称: Piercer of microtubule wall 2 protein / タイプ: protein_or_peptide / ID: 25 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 13.728513 KDa
配列文字列:
MARETDCDLD KKTSLTSDAE MRPEPPALCV NPGNPVFSCM LDPKTLHTAT SLSKAQMIMY KTSASQYGAF SPRPFFFPCK FLPQEQAFT EHLKTTGFYQ NNSLNVGPDR TRTIDSPNYQ HTL

UniProtKB: Piercer of microtubule wall 2 protein

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分子 #26: Cilia- and flagella-associated protein 276

分子名称: Cilia- and flagella-associated protein 276 / タイプ: protein_or_peptide / ID: 26 / コピー数: 4 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 18.960092 KDa
配列文字列:
MLQPQETFSN PALRDEDKHL GNLWASKKSL YKNPAHLAQQ QDPWSRLSST PTATSRSRDT FFDSKIPKDD LDFRLATLYN HHTGAFKNK TEILLHQETI EDIQGTKIQF PGECFHAPSA PITSRTTIRH WINPKKESIH SIQGSIVSPH TAATNGGYSR K NDGGFFST

UniProtKB: Cilia- and flagella-associated protein 276

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分子 #27: RIB43A-like with coiled-coils protein 2

分子名称: RIB43A-like with coiled-coils protein 2 / タイプ: protein_or_peptide / ID: 27 / コピー数: 4 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 45.328156 KDa
配列文字列: MEVAMSKDLQ QEANLAKKRY IDLCRQGRIF DARNRIIGGD TQAWDFQVRD QKIKEITDKA RHEAFAAEMK HNDKVMCMAH DREQRHRKQ LCRAINDFQQ NFQKPETRRE FDLSDPLALQ KELPARISDN DMRNTISGMQ KFMGEDLNFQ ERRRFQKEQS R EWFLQQHG ...文字列:
MEVAMSKDLQ QEANLAKKRY IDLCRQGRIF DARNRIIGGD TQAWDFQVRD QKIKEITDKA RHEAFAAEMK HNDKVMCMAH DREQRHRKQ LCRAINDFQQ NFQKPETRRE FDLSDPLALQ KELPARISDN DMRNTISGMQ KFMGEDLNFQ ERRRFQKEQS R EWFLQQHG EREKARADHL LAEHLHTQTR LKFDETAREL MKLEGSTRKE VCAAVKAFNK NQVVELTERK RQEKQQEQED NM TEITNLL HGDLLSENPR PVASSFGSHR VVLDRWKGMN REQLEEIWFT QKRQIQEKLR LQEEERQHSM DWDLRRIRKA HAS LLHERQ QQRLLREQRR ALDCSNLNLA RQQYLQKKQM NTASSSQPTE DYFSQFNTRS R

UniProtKB: RIB43A-like with coiled-coils protein 2

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分子 #28: Protein Flattop

分子名称: Protein Flattop / タイプ: protein_or_peptide / ID: 28 / コピー数: 3 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 20.575123 KDa
配列文字列: MATNYSANQY EKAYLPTYLQ NWSPARPTKE KIAAHEGYTQ IIANDRGHLL PSVPRSKASP WGSFMGTWQM PLKIPPAKVT LTARTTTAA DNLTKWIHKN PDLLNACNGL RPEISGKPFD PDSQTKQKKS VTKTVQQAPN PTIIPSSPVI QGDNPDEPQS S HPSAGHTP ...文字列:
MATNYSANQY EKAYLPTYLQ NWSPARPTKE KIAAHEGYTQ IIANDRGHLL PSVPRSKASP WGSFMGTWQM PLKIPPAKVT LTARTTTAA DNLTKWIHKN PDLLNACNGL RPEISGKPFD PDSQTKQKKS VTKTVQQAPN PTIIPSSPVI QGDNPDEPQS S HPSAGHTP GPQTPVNSPN NPPPSPCKST K

UniProtKB: Protein Flattop

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分子 #29: Cilia- and flagella-associated protein 52

分子名称: Cilia- and flagella-associated protein 52 / タイプ: protein_or_peptide / ID: 29 / コピー数: 3 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 68.322164 KDa
配列文字列: MEEQVLPELD VAELELQAVI GFNGHVPNGL KCHPDQEHLI YPLGCTVLIQ AINTNEQNFL HGHGNNVSCV TISKEGDYIA SGQVTFMGF KADIILWDFK KRELIARLSL HKGKIEALAF SPNDLYLVSL GGPDDGSVVV WSIAKRDAIC GSPAAGLNVG N ATSVVFSR ...文字列:
MEEQVLPELD VAELELQAVI GFNGHVPNGL KCHPDQEHLI YPLGCTVLIQ AINTNEQNFL HGHGNNVSCV TISKEGDYIA SGQVTFMGF KADIILWDFK KRELIARLSL HKGKIEALAF SPNDLYLVSL GGPDDGSVVV WSIAKRDAIC GSPAAGLNVG N ATSVVFSR CRDEMFVTAG NGTIRVWELD LPNRKIWPTE CQTGQMKRIV LSTGMADDDS FFYLGTTTGD ILKMNPKTKL LA DTGPVKD KFSLGVSALR CLKMGGLLVG SGAGLLIFCK SPSYKPIKKV QLQGGITSIT LRGEGHQFFV GTEESHIYRV NFT DFKETL IATCHFEAVQ DIVFPFGTAE LFATCAKKDI RVWHTMSKRE LLRITVPNMT CHGIDFMRDG KSIISAWDDG KIRA FAPES GRLMYTINSA HRIGVTAIAT TSDCKRIISG GGEGEVRVWQ VGCQTQKLEE ALKEHKSSVS CIRVKKNNEE CVTAS TDGT CIIWDLVRLR RNQMILANTL FQCVCYHPEE FQIITSGTDR KIAYWEVFDG SVIRELEGSL SGSINGMDIT QEGGHF VTG GHDHLVKVWD YNEGEVTHVG VGHSGNIMAM RISPGNQYIV SVSADGAILR WKYPFAS

UniProtKB: Cilia- and flagella-associated protein 52

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分子 #30: EF-hand calcium-binding domain-containing protein 6

分子名称: EF-hand calcium-binding domain-containing protein 6 / タイプ: protein_or_peptide / ID: 30 / コピー数: 3 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 176.028312 KDa
配列文字列: MKRNGTRLNF AKANSTKSGS TRARDLMNKM SIIPEWHSLY SNTRKLPCSR PHSSPCKMQR TIFQDLCRPS SSTTAIANPV LSYLDIERI LAQKISSRRD DIKKVFQILD RNHNQMVTKG DLKRVITAFL IPLTKDQFQD LLAQIPISSL GNVPYLEFLS R FGGGIDIN ...文字列:
MKRNGTRLNF AKANSTKSGS TRARDLMNKM SIIPEWHSLY SNTRKLPCSR PHSSPCKMQR TIFQDLCRPS SSTTAIANPV LSYLDIERI LAQKISSRRD DIKKVFQILD RNHNQMVTKG DLKRVITAFL IPLTKDQFQD LLAQIPISSL GNVPYLEFLS R FGGGIDIN INGIKRVNEN EVDNRRTVKE VQLTEKIFRN MRSIRKVFQV MDVNNTGLVQ PQELRRVLET FCLRMQDGDY EK FLEQYNI DKTTAVDYNA FLKNLSVKND ASFKYLLSNA AELSRETQQG KNGKRLLDTG SSEDVWKNYS LDDLEKTFCQ EFS KSYEKI EKALSAGDPS KGGYISLNYL KVVLDTFIYR LPRRIFIQLI RRFGLKTSTK INWKQFLTAI YERQKLEVSK TLPL KKRSS TEARNRSRKE NIIKKLFKYS EDRYTALKKT LLIISSTPSG HITWEELRHI LNCMVAKLND SEFSELKQTF DPEGT GAVR VNSLLDVLDD STKVRKMSPS TDTKTPLPVA WDSVEELVLD SITRNLQAFY SMLQSYDLRD TGTIGKNNFR KVMRVF CPY LSNEHLVRFS SKFQEAGSGR ILYKKFLLSI GVGIPPPTPP LSSPKVQLSD QFQIEEPGQQ DERTQPSGEK TSEINNM TK EEVIDGLKHR IQQKDPVFRK QFLSISKEPD VKINQEEFRK VLERSGMPMN DCQYAMLASK LGFKNEEGMS YQDFTMGF E DCMLSGLETV PLQSRTASRT NMDEHFISAE ECLRIFPKKL KESFRDVYSA FFRIDLDRDG IISMHDFHRL LQYLQLNMV DLEFERFLSL LGLRLSVTLN FREFQNLCEK RPWKSDEAPQ RLIRCKQKVA DSELACEQAH QYLIMKAKTR WADLSKNFIE TDNEGNGIL RRRDIKNSLY GFDIPLTPRE FEKLWQNYDT EGRGYITYQE FLHRLGIRYS PKVHRPYKED YFNFLGHFTK P KQVQEEIQ ELQQISEREK LMNHYEEISK AFNAMEKSKP VALCRVQKVL QECGCPLKEE ELISLLKSLD VSVHNNHIDP VE FLRALEI SWASKARPKE KEESSPPPIS FSKVTPDEVI KTMQEVVESS QPALVEAFSA LDKEDTGFVK AMEFGDVLRS VCQ KLTDNQ YHYFLRRLRL HLTPNIHWKY FLENFSTFQD ETADDWAENM PKAPPPMSPK ETAHRDIVAR VQKAVASHYH TIVQ EFENF DTLKSNTVSR DEFRSICTRH IQILTDEQFD RLWSELPVNA KGRLKYQDFL SKLSIERVPS PPMAAGDSGE STMAQ RGSS APEFSQGTRS NLYSPPRDSR VGLKSRSHPC TPVGTPPLQN CEPIESRLRK QIQGCWRELL RECKEKDTDK QGTISA AEF LALVEKFKLD ISREESQQLI VKYDLKNNGK FAYCDFIQSC VLLLKAKETS LMRRMRIQNA DKMKEAGMET PSFYSAL LR IQPKIVHCWR PMRRSFKTYD KNGTGLLSVA DFRKVLRQYS INLSEEEFFH VLEYYDKSLS SKISYNDFLR AFLQ

UniProtKB: EF-hand calcium-binding domain-containing protein 6

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分子 #31: Cilia and flagella-associated protein 77

分子名称: Cilia and flagella-associated protein 77 / タイプ: protein_or_peptide / ID: 31 / コピー数: 3 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 32.78602 KDa
配列文字列: MPDPAKPGKD LTAWKKKKQP VHRTVSQICP PPRRPLTVVD IRTGMENERL GVVRDSMFQN PLIVKAELGK PRERSCSLPG INFNYGLYI RGLDGGVPEA IGHWNVFKQQ PTCPHELTRN YIAMNRGAVK AGLVTARENM LYRELNDIRI NDQEDRRQKE P PPIPPNMT ...文字列:
MPDPAKPGKD LTAWKKKKQP VHRTVSQICP PPRRPLTVVD IRTGMENERL GVVRDSMFQN PLIVKAELGK PRERSCSLPG INFNYGLYI RGLDGGVPEA IGHWNVFKQQ PTCPHELTRN YIAMNRGAVK AGLVTARENM LYRELNDIRI NDQEDRRQKE P PPIPPNMT FGIRSRPSTP FFDLLQHRYQ QLWVQEQKAT QQAIKMEKKQ KVILGKLYET RSSQLRKYKP PVKLDALWHM PH FKKVASH LATFPTEADR QRALKAHKEE YAVRQGTLRM GNYTHP

UniProtKB: Cilia- and flagella-associated protein 77

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分子 #32: Sperm-associated antigen 8

分子名称: Sperm-associated antigen 8 / タイプ: protein_or_peptide / ID: 32 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 50.591805 KDa
配列文字列: METTESTEGS LSRSCDVQPS SERLDTPSEP VPSSSSSPRS TAPAEAPAQY SVLTEPSSDS LYGAPCPPAH HRGHGFGFQP FYVSCIPQD PCNMADLSSR ADPTSSYPCH SSVHGSGSGT CGLGQSSEPS QGSGPTSGPA PASVPSLVSG PDSASGPDSS A SGPALASG ...文字列:
METTESTEGS LSRSCDVQPS SERLDTPSEP VPSSSSSPRS TAPAEAPAQY SVLTEPSSDS LYGAPCPPAH HRGHGFGFQP FYVSCIPQD PCNMADLSSR ADPTSSYPCH SSVHGSGSGT CGLGQSSEPS QGSGPTSGPA PASVPSLVSG PDSASGPDSS A SGPALASG PGPADPGQGP KFSTCIPQGY RCIPVDLAPD YNAWCQHLHW KPQRSWEPLQ VSEPGVRGPY KPPEPGALGP CE PCEPCEP PEAESEETLC KARPRGQCLL YNWEEERATN QLDQIPPLQD GSESYFFRHG HQGLLTTQPQ SPMSSSTTQR DSY QLPRHI CQPLRGKREA MLEMLLRHQI CKEVQAEQEP ARKLFETESV THHDYRVELV RAAPPASTKP HDYRQEQPET FWIQ RAARL PGVSDIRTLD TPFRKNCSFS TPVPLSLGQP LPYELESGPH QVGVISSLAC QGGGQGCGRT KTTPI

UniProtKB: Sperm-associated antigen 8

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分子 #33: Cilia- and flagella-associated protein 45

分子名称: Cilia- and flagella-associated protein 45 / タイプ: protein_or_peptide / ID: 33 / コピー数: 4 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 65.962016 KDa
配列文字列: MPLRPGDASS SASTASNRSR TRTRYRTKAM NSEVDESLFG GVKPSSQGKS DSPIVVIHDK HAIRKTLSAL GLEHKTETIQ LITRDMVRE LIVPTEDPSG ESLIISPEEF ERIKWASQVL TKEELNAREQ ALKKEKEGIL EAVTIRKKIM KQKEMTWNNN K KLSDLEEV ...文字列:
MPLRPGDASS SASTASNRSR TRTRYRTKAM NSEVDESLFG GVKPSSQGKS DSPIVVIHDK HAIRKTLSAL GLEHKTETIQ LITRDMVRE LIVPTEDPSG ESLIISPEEF ERIKWASQVL TKEELNAREQ ALKKEKEGIL EAVTIRKKIM KQKEMTWNNN K KLSDLEEV ARERAQNLLQ RADKLRMEQE EELKDMSKII LNAKCHAIRD AQILEKQQIQ KELDEEERRL DHMMEIDRRE SL QRQEDRE RKRREERVRG KRHIVEQIKK NEEERSLQAE HREQEKEQML AYLDRLQEED LQDLERRHQE KLKMQAEIKR IND ENQRQK AEMLAQERLA DQMVMEFTKK KMAREAEYEA EQEKIRREKE KEIARLRALQ EKAQDYQAEQ DALRAKRNQE VADR EWRRK EKENAQKKIE TEEKLRKSRL EQVAFKEHTL AVQVQRDRDE FERILRAQRE QIEREKQEQE KKAKGCLQHA NELRR QVRE NQQKHVQNRL ATFEEGRRLK EEAEKRRERI EDIKKQKLEE LRATGLPEKY CIEVERKANI LPATSVN

UniProtKB: Cilia- and flagella-associated protein 45

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分子 #34: Cilia- and flagella-associated protein 20

分子名称: Cilia- and flagella-associated protein 20 / タイプ: protein_or_peptide / ID: 34 / コピー数: 7 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 22.781389 KDa
配列文字列: MFKNTFQSGF LSILYSIGSK PLQIWDKKVR NGHIKRITDN DIQSLVLEIE GTNVSTTYIT CPADPKKTLG IKLPFLVMII KNLKKYFTF EVQVLDDKNV RRRFRASNYQ STTRVKPFIC TMPMRLDDGW NQIQFNLSDF TRRAYGTNYI ETLRVQIHAN C RIRRVYFS ...文字列:
MFKNTFQSGF LSILYSIGSK PLQIWDKKVR NGHIKRITDN DIQSLVLEIE GTNVSTTYIT CPADPKKTLG IKLPFLVMII KNLKKYFTF EVQVLDDKNV RRRFRASNYQ STTRVKPFIC TMPMRLDDGW NQIQFNLSDF TRRAYGTNYI ETLRVQIHAN C RIRRVYFS DRLYSEDELP AEFKLYLPVQ NKAKQ

UniProtKB: Cilia- and flagella-associated protein 20

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分子 #35: Parkin coregulated gene protein homolog

分子名称: Parkin coregulated gene protein homolog / タイプ: protein_or_peptide / ID: 35 / コピー数: 6 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 27.763268 KDa
配列文字列: MPKRTKLLPQ QTFQVHQPRS LVSEGFTVKA MMKNSVVRGP PVAGAFKERP AKPTTFRKCY ERGDFPIALE HDSKGNKIAW KVEIEKLDY HHYLPLFFDG LSEMTFPYEF FARRGIHDML EHGGNKILPV IPQLIIPIKN ALNLRNRQII CVTLKVLQHL V VSSEMVGE ...文字列:
MPKRTKLLPQ QTFQVHQPRS LVSEGFTVKA MMKNSVVRGP PVAGAFKERP AKPTTFRKCY ERGDFPIALE HDSKGNKIAW KVEIEKLDY HHYLPLFFDG LSEMTFPYEF FARRGIHDML EHGGNKILPV IPQLIIPIKN ALNLRNRQII CVTLKVLQHL V VSSEMVGE ALLPYYRQIL PILNIFKNMN VNSGDGIDYS QQKRENIGDL IQETLEAFER YGGEDAFINI KYMVPTYESC LL N

UniProtKB: Parkin coregulated gene protein homolog

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分子 #36: Cilia- and flagella-associated protein 210

分子名称: Cilia- and flagella-associated protein 210 / タイプ: protein_or_peptide / ID: 36 / コピー数: 2 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 65.26652 KDa
配列文字列: MQVRFGRRSG QAKESQGMDC FEKEEIPYPP LLPSKVDLQQ ITIIPHAEWE RIRDSLNRLT REAAVLRAER AAKKKMHVKS QELVKHWTN TYAGMKEQKL KAKQKRDEEI EAERKVLDLE EEIYKEGERK KAIESARQCQ FHQTERVKRF HSGLLLSRVM K ERDVQIQY ...文字列:
MQVRFGRRSG QAKESQGMDC FEKEEIPYPP LLPSKVDLQQ ITIIPHAEWE RIRDSLNRLT REAAVLRAER AAKKKMHVKS QELVKHWTN TYAGMKEQKL KAKQKRDEEI EAERKVLDLE EEIYKEGERK KAIESARQCQ FHQTERVKRF HSGLLLSRVM K ERDVQIQY KKNAVKSDKK WEEQVKLNDE KAFKEDQEKE EKRRRERVAL AEDHLKQIEE HKEEEEARKK SEEKDAEEMK RQ NLLYEIE MKKNLSKKQE EIDTNRKLLL DNMHNKNIIR AVEQQQQEEE DEKIRKFIKA KKRLIQMRMD KDAETHRLME ERR ERINNF LSKLIKEKLD TEDLIIARDI SEADAELEKR EKEKHEKNQA DLKAIAEYRA SVMKNKEEEE RQRKIEAKEQ LQAV LKADK IFQELEKEKS LKVTREKLEI QDAHIQQIAI NKYNAKQMKE EELDYWRLTD ALTVEKEKEF EKYAREVINF ESEST KKYA YPMVKAVQEG VGGGRGPPFV GRGGIRPSYQ ATDATGVQLP CFKSQGSKYN DFQKSKRRLG FTW

UniProtKB: Cilia- and flagella- associated protein 210

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分子 #37: Sperm acrosome-associated protein 9

分子名称: Sperm acrosome-associated protein 9 / タイプ: protein_or_peptide / ID: 37 / コピー数: 23 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 19.512373 KDa
配列文字列:
MNEVKESLRS IEQKYKLFQQ QQFTFIAALE HCRENAHDKI RPISSIEQVQ SYMEHYCNNS THRRILIMFM DICSELSKLC QHFEALHSG TPVTNSLLEK CKTLVSQSND LSSLRAKYPH EVVNHLSCDE ARNHYGGVVS LIPIVLDFMK EWIAHSEKLP R KVLQHGTT

UniProtKB: Sperm acrosome-associated protein 9

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分子 #38: Cilia- and flagella-associated protein 141

分子名称: Cilia- and flagella-associated protein 141 / タイプ: protein_or_peptide / ID: 38 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Mus musculus (ハツカネズミ)
分子量理論値: 12.278145 KDa
配列文字列:
MSAEKMTKLE ENLQRAVALK KTVDRWRNFH IHCMWQTTLD QRRNLFAALR MKDTKEQELA LSNKQLLVVR QAALHELFEK EYQQYQQEL NQMGKAFYEE RL

UniProtKB: Cilia- and flagella-associated protein 141

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分子 #39: GUANOSINE-5'-TRIPHOSPHATE

分子名称: GUANOSINE-5'-TRIPHOSPHATE / タイプ: ligand / ID: 39 / コピー数: 279 / 式: GTP
分子量理論値: 523.18 Da
Chemical component information

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP / GTP, エネルギー貯蔵分子*YM

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実験情報

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構造解析

手法クライオ電子顕微鏡法
解析サブトモグラム平均法
試料の集合状態cell

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試料調製

緩衝液pH: 7
凍結凍結剤: ETHANE

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電子顕微鏡法

顕微鏡FEI TITAN KRIOS
撮影フィルム・検出器のモデル: GATAN K2 QUANTUM (4k x 4k)
検出モード: SUPER-RESOLUTION / 平均電子線量: 3.0 e/Å2
電子線加速電圧: 300 kV / 電子線源: FIELD EMISSION GUN
電子光学系照射モード: SPOT SCAN / 撮影モード: BRIGHT FIELD / Cs: 2.7 mm / 最大 デフォーカス（公称値）: 5.0 µm / 最小 デフォーカス（公称値）: 1.0 µm
実験機器
モデル: Titan Krios / 画像提供: FEI Company

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画像解析

最終 再構成想定した対称性 - 点群: C1 (非対称) / 解像度のタイプ: BY AUTHOR / 解像度: 6.5 Å / 解像度の算出法: FSC 0.143 CUT-OFF / 使用したサブトモグラム数: 17450
抽出トモグラム数: 689 / 使用した粒子像数: 17450
最終 角度割当タイプ: MAXIMUM LIKELIHOOD

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万見について

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お知らせ

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2022年2月9日: EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

  • EMDBのヘッダファイルのバージョン3が、公式のフォーマットとなりました。
  • これまでは公式だったバージョン1.9は、アーカイブから削除されます。

関連情報:EMDBヘッダ

外部リンク:wwPDBはEMDBデータモデルのバージョン3へ移行します

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2020年8月12日: 新型コロナ情報

新型コロナ情報

URL: https://pdbj.org/emnavi/covid19.php

新ページ: EM Navigatorに新型コロナウイルスの特設ページを開設しました。

関連情報:Covid-19情報 / 2020年3月5日: 新型コロナウイルスの構造データ

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2020年3月5日: 新型コロナウイルスの構造データ

新型コロナウイルスの構造データ

関連情報:万見生物種 / 2020年8月12日: 新型コロナ情報

外部リンク:COVID-19特集ページ - PDBj / 今月の分子2020年2月：コロナウイルスプロテーアーゼ

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2019年1月31日: EMDBのIDの桁数の変更

EMDBのIDの桁数の変更

  • EMDBエントリに付与されているアクセスコード(EMDB-ID)は4桁の数字(例、EMD-1234)でしたが、間もなく枯渇します。これまでの4桁のID番号は4桁のまま変更されませんが、4桁の数字を使い切った後に発行されるIDは5桁以上の数字(例、EMD-12345)になります。5桁のIDは2019年の春頃から発行される見通しです。
  • EM Navigator/万見では、接頭語「EMD-」は省略されています。

関連情報:Q: 「EMD」とは何ですか？ / 万見/EM NavigatorにおけるID/アクセスコードの表記

外部リンク:EMDB Accession Codes are Changing Soon! / PDBjへお問い合わせ

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2017年7月12日: PDB大規模アップデート

PDB大規模アップデート

  • 新バージョンのPDBx/mmCIF辞書形式に基づくデータがリリースされました。
  • 今回の更新はバージョン番号が4から5になる大規模なもので、全エントリデータの書き換えが行われる「Remediation」というアップデートに該当します。
  • このバージョンアップで、電子顕微鏡の実験手法に関する多くの項目の書式が改定されました(例：em_softwareなど)。
  • EM NavigatorとYorodumiでも、この改定に基づいた表示内容になります。

外部リンク:wwPDB Remediation / OneDepデータ基準に準拠した、より強化された内容のモデル構造ファイルが、PDBアーカイブで公開されました。

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万見 (Yorodumi)

幾万の構造データを、幾万の視点から

  • 万見(Yorodumi)は、EMDB/PDB/SASBDBなどの構造データを閲覧するためのページです。
  • EM Navigatorの詳細ページの後継、Omokage検索のフロントエンドも兼ねています。

関連情報:EMDB / PDB / SASBDB / 3つのデータバンクの比較 / 万見検索 / 2016年8月31日: 新しいEM Navigatorと万見 / 万見文献 / Jmol/JSmol / 機能・相同性情報 / 新しいEM Navigatorと万見の変更点

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