+Open data
-Basic information
Entry | Database: PDB / ID: 1au8 | ||||||
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Title | HUMAN CATHEPSIN G | ||||||
Components | CATHEPSIN G | ||||||
Keywords | HYDROLASE/HYDROLASE INHIBITOR / INFLAMMATION / SPECIFICITY / HYDROLASE-HYDROLASE INHIBITOR COMPLEX | ||||||
Function / homology | Trypsin / Trypsin-like serine proteases / Thrombin, subunit H / Beta Barrel / Mainly Beta / N-(3-carboxypropanoyl)-L-valyl-N-[(1R)-5-amino-1-phosphonopentyl]-L-prolinamide / Chem-0H8 / : Function and homology information | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | X-RAY DIFFRACTION / Resolution: 1.9 Å | ||||||
Authors | Medrano, F.J. / Bode, W. / Banbula, A. / Potempa, J. | ||||||
Citation | Journal: to be published Title: HUMAN CATHEPSIN G Authors: Medrano, F.J. / Bode, W. / Banbula, A. / Potempa, J. | ||||||
History |
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Remark 650 | HELIX DETERMINATION METHOD: TAKEN FROM RELEASED PDB ENTRY 1CGH | ||||||
Remark 700 | SHEET DETERMINATION METHOD: TAKEN FROM RELEASED PDB ENTRY 1CGH |
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1au8.cif.gz | 56.9 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1au8.ent.gz | 44.2 KB | Display | PDB format |
PDBx/mmJSON format | 1au8.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 1au8_validation.pdf.gz | 449.6 KB | Display | wwPDB validaton report |
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Full document | 1au8_full_validation.pdf.gz | 457 KB | Display | |
Data in XML | 1au8_validation.xml.gz | 7.1 KB | Display | |
Data in CIF | 1au8_validation.cif.gz | 10.7 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/au/1au8 ftp://data.pdbj.org/pub/pdb/validation_reports/au/1au8 | HTTPS FTP |
-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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1 |
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Unit cell |
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-Components
#1: Protein | Mass: 25484.211 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Homo sapiens (human) / References: UniProt: P08311, EC: 3.4.21.20 |
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#2: Chemical | ChemComp-0H8 / |
#3: Water | ChemComp-HOH / |
-Experimental details
-Experiment
Experiment | Method: X-RAY DIFFRACTION / Number of used crystals: 1 |
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-Sample preparation
Crystal | Density Matthews: 1.97 Å3/Da / Density % sol: 37.63 % |
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Crystal grow | pH: 7 / Details: pH 7.0 |
-Data collection
Diffraction | Mean temperature: 293 K |
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Diffraction source | Wavelength: 1.5418 |
Detector | Type: MARRESEARCH / Detector: IMAGE PLATE / Date: Sep 15, 1995 |
Radiation | Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength: 1.5418 Å / Relative weight: 1 |
Reflection | Num. obs: 18433 / % possible obs: 96.3 % / Rmerge(I) obs: 0.134 |
-Processing
Software |
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Refinement | Resolution: 1.9→6 Å / σ(F): 2
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Refinement step | Cycle: LAST / Resolution: 1.9→6 Å
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Refine LS restraints |
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LS refinement shell | Highest resolution: 1.9 Å /
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