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-Structure paper
Title | Molecular basis of global promoter sensing and nucleosome capture by the SWR1 chromatin remodeler |
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Journal, issue, pages | Cell(Cambridge,Mass. ), Year 2024 |
Publish date | Mar 13, 2024 (structure data deposition date) |
Authors | Louder RK / Park G / Ye Z / Cha JS / Gardner AM / Lei Q / Ranjan A / Hollmuller E / Stengel F / Pugh BF / Wu C |
External links | Cell(Cambridge,Mass. ) / Search PubMed |
Methods | EM (single particle) |
Resolution | 3.3 - 7.3 Å |
Structure data | EMDB-44074, PDB-9b1d: EMDB-44075, PDB-9b1e: EMDB-44093: Cryo-EM structure of native SWR1, free complex (composite structure) EMDB-44106: Cryo-EM structure of native SWR1 bound to DNA (consensus map) EMDB-44107: RuvBL core from SWR1-DNA complex (focused refinement) EMDB-44108: Swr1 ATPase domain from SWR1-DNA complex (focused refinement) EMDB-44109: Arp6/Swc6 module from SWR1-DNA complex (focused refinement) EMDB-44110: Cryo-EM structure of native SWR1 bound to DNA (unmasked refinement filtered by local resolution) EMDB-44307: Cryo-EM structure of native SWR1 bound to nucleosome (consensus map filtered by local resolution) EMDB-44308: RuvBL-associated core from SWR1-nucleosome complex (focused refinement) EMDB-44309: Nucleosome and bound Swr1 ATPase from SWR1-nucleosome complex (focused refinement) EMDB-44310: Swc3-Swc2 subcomplex from SWR1-nucleosome complex (focused refinement) EMDB-44311: Cryo-EM structure of native SWR1, free complex (consensus map filtered by local resolution) EMDB-44312: RuvBL core from free SWR1 complex (focused refinement) EMDB-44313: Arp6/Swc6 module from free SWR1 complex (focused refinement) EMDB-46065: Cryo-EM structure of native SWR1 bound to DNA in the absence of nucleotide (composite structure) EMDB-46066: Cryo-EM structure of native SWR1 bound to DNA in the absence of nucleotide (consensus map) EMDB-46067: RuvBL core from SWR1(apo)-DNA complex (focused refinement) EMDB-46068: Arp6/Swc6 module from SWR1(apo)-DNA complex (focused refinement) EMDB-46069: Swr1 ATPase domain from SWR1(apo)-DNA complex (focused refinement) |
Chemicals | ChemComp-AGS: ChemComp-MG: ChemComp-ZN: ChemComp-ADP: ChemComp-BEF: |
Source |
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Keywords | GENE REGULATION / Chromatin Remodeler / Snf2 family ATPase / histone exchange / H2A.Z |