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TitleCrystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase reveals a unique binding mode as a alpha-furanosyl hemiketal of substrates.
Journal, issue, pagesSci Rep, Vol. 14, Page 14602-14602, Year 2024
Publish dateJan 16, 2024 (structure data deposition date)
AuthorsAkagashi, M. / Watanabe, S. / Kwiatkowski, S. / Drozak, J. / Terawaki, S. / Watanabe, Y.
External linksSci Rep / PubMed:38918500
MethodsX-ray diffraction
Resolution1.27 - 1.77 Å
Structure data

PDB-8xwk:
Crystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase from Herbaspillum huttiense (apo form)
Method: X-RAY DIFFRACTION / Resolution: 1.27 Å

PDB-8y11:
Crystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase bound to NAD(H) and sulfate ion
Method: X-RAY DIFFRACTION / Resolution: 1.77 Å

PDB-8y46:
Crystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase bound to L-KDF or L-2,4-DKDF
Method: X-RAY DIFFRACTION / Resolution: 1.29 Å

PDB-8y4b:
Crystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase bound to L-2,4-DKDF and NADH
Method: X-RAY DIFFRACTION / Resolution: 1.67 Å

PDB-8y4j:
Crystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase bound to D-KDP
Method: X-RAY DIFFRACTION / Resolution: 1.51 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-SO4:
SULFATE ION

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-GOL:
GLYCEROL

PDB-1lxa:
UDP N-ACETYLGLUCOSAMINE ACYLTRANSFERASE

PDB-1lxb:
Unknown entry

PDB-1lxd:
CRYSTAL STRUCTURE OF THE RAS INTERACTING DOMAIN OF RALGDS, A GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR OF RAL PROTEIN

Source
  • herbaspirillum huttiense (bacteria)
KeywordsOXIDOREDUCTASE / dehydrogenase / Rossmann Fold

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