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TitleCharacterization of two novel antibody fragments for obtaining cryo-EM structures of GPCR-G protein complexes
Journal, issue, pagesTo Be Published
Publish dateMay 11, 2023 (structure data deposition date)
AuthorsPamula F / Tejero O / Muehle J / Thoma R / Schertler GFX / Marino J / Tsai C-J
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.21 - 5.9 Å
Structure data

17343

8p12

EMDB-17343, PDB-8p12:
Cryo-EM structure of Rhodopsin-Gi bound to antibody fragment Fab13
Method: EM (single particle) / Resolution: 3.21 Å

17344

8p13

EMDB-17344, PDB-8p13:
Cryo-EM structure of Rhodopsin-Gi bound with antibody fragments scFv16 and Fab79, conformation 1
Method: EM (single particle) / Resolution: 5.2 Å

17345

8p15

EMDB-17345, PDB-8p15:
Cryo-EM structure of Rhodopsin-Gi bound with antibody fragments scFv16 and Fab79, conformation 2
Method: EM (single particle) / Resolution: 5.9 Å

Source
  • bos taurus (cattle)
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsSIGNALING PROTEIN / GPCR / Rhodopsin / G protein / Fab

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